[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$f65-g5LTUgHIk8dGZIHhGe2pKpxnfW0g-O4HGxk3yxcs":3,"$f4Vc5zTMAezr7UWsjh2AOUXGjEKfQ8_5JjBl6vM1UHH8":8,"$fjkhGaOD7v0pr-TTpry0S0OtrZ8mv4qKc8UVMxBdKE4g":55,"$fJmCmzHRVnd-qiLsPwlrCMsmPzrTlyO_ufcY36oWznHo":59},{"code":4,"msg":5,"message":6,"data":6,"success":7},401,"认证失败，无法访问系统资源",null,false,{"code":9,"msg":10,"message":6,"data":11,"success":54},200,"操作成功",{"id":12,"specialistId":13,"specialistAssistants":14,"profilePhoto":15,"specialistName":16,"hospital":17,"department":18,"postsTitle":19,"materialTotal":20,"videoTotal":21,"isConcern":7,"title":22,"coverVertical":23,"coverAcross":24,"content":25,"description":26,"views":27,"likes":21,"isThumbsUp":7,"isCollection":7,"collections":21,"createTime":28,"seoTitle":22,"seoKeywords":29,"seoDescription":30,"shelvesTime":31,"version":32,"menus":33,"menuId":35,"type":42,"quality":53,"commentCount":21,"isComment":42},67467,867178,[],"https://cdn.yishi-tong.com/console/store-unknown/uF7OMd0P_hB1LaAPsAH23kXFsYY6stA4.png","王永超","赵县人民医院","肿瘤科","主治医师",56,0,"肺癌II期治疗：顺铂与昂丹司琼的科学用药指南","","https://ystcdn.venuertc.com/venue/AI/1de795f5-5d7b-4996-894a-a7ec7abed9dd.jpg","\u003Cdiv class=\"lungca_drugguide\">\n  \u003Ch1 id=\"material_title\" class=\"lungca_drugguide-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">肺癌II期治疗：顺铂与昂丹司琼的科学用药指南\u003C/h1>\n  \n  \u003Cdiv class=\"lungca_drugguide-section lungca_drugguide-intro\">\n    \u003Cdiv class=\"lungca_drugguide-bg lungca_drugguide-bg01\">\u003C/div>\n    \u003Ch2 class=\"lungca_drugguide-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>👀\u003C/span> 顺铂与昂丹司琼，怎么用才安全高效？\u003C/h2>\n    \u003Cp class=\"lungca_drugguide-introtext\">\n      有些药品名大家听说得多，比如顺铂（Cisplatin）和昂丹司琼（Ondansetron）。顺铂用于抗肿瘤，昂丹司琼常用于预防化疗相关的恶心呕吐。正确使用这两种药很关键。此文将通过7个实用细节，帮你全面掌握它们的科学用法，做到用药既安全又有效。\u003C/p>\n  \u003C/div>\n  \n  \u003C!-- 1 剂型特点与用药技巧 -->\n  \u003Csection class=\"lungca_drugguide-section\">\n    \u003Cdiv class=\"lungca_drugguide-bg lungca_drugguide-bg02\">\u003C/div>\n    \u003Ch2 class=\"lungca_drugguide-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>💉\u003C/span> 剂型特点与用药技巧\u003C/h2>\n    \u003Cp>\n      \u003Cb>顺铂：\u003C/b>常用剂型为注射剂。每瓶含有不同规格（常见有10mg、50mg），实际使用时由医护人员根据具体体重或方案计算总量。正确做法：避免自行配药，务必由专业人员操作，并根据说明严格对照规格。顺铂不建议口服，也不与其他注射液随意混合。\n    \u003C/p>\n    \u003Cp>\n      \u003Cb>昂丹司琼：\u003C/b>常见剂型有注射液、口服片和口服溶液。注射液按说明书剂量使用，多为每次8mg，常在化疗前半小时使用。片剂需整片吞服，不能嚼碎。正确做法：服药时搭配少量温水，切忌用果汁或牛奶。\n    \u003C/p>\n    \u003Cp>\n      正确做法：所有药品剂型使用均需按药物说明书及医生建议操作，避免自行更换剂型。\n    \u003C/p>\n  \u003C/section>\n\n  \u003C!-- 2 给药时间与方式 -->\n  \u003Csection class=\"lungca_drugguide-section\">\n    \u003Cdiv class=\"lungca_drugguide-bg lungca_drugguide-bg03\">\u003C/div>\n    \u003Ch2 class=\"lungca_drugguide-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>⏰\u003C/span> 给药时间与最佳使用方法\u003C/h2>\n    \u003Cp>\n      \u003Cb>顺铂：\u003C/b>多在治疗日由医护人员静脉注射，需严格控制滴速。具体用法通常是分一定时长滴入静脉（如2-4小时）。化疗当天使用，避免与其他化疗药同瓶混合。\n    \u003C/p>\n    \u003Cp>\n      \u003Cb>昂丹司琼：\u003C/b>正确做法是在顺铂化疗开始前半小时静脉注射8mg，后续可根据情况口服补充。部分方案会指导每日1-2次，每次间隔时间需固定，避免超剂量。\n    \u003C/p>\n    \u003Cp>\n      正确做法：严格按照医生设定的时间使用，不提前或延后。\n    \u003C/p>\n  \u003C/section>\n  \n  \u003C!-- 3 适应症、禁忌症与特殊情况 -->\n  \u003Csection class=\"lungca_drugguide-section\">\n    \u003Cdiv class=\"lungca_drugguide-bg lungca_drugguide-bg04\">\u003C/div>\n    \u003Ch2 class=\"lungca_drugguide-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>🚫\u003C/span> 适应症与禁忌，谁能用，谁不能用？\u003C/h2>\n    \u003Cp>\n      \u003Cb>顺铂：\u003C/b>用于抗肿瘤治疗。禁忌症包括：严重肾脏功能损害、听力严重受损、孕妇及哺乳期妇女，以及对铂类药物过敏者。肝肾功能异常者需调整或避免使用。\n    \u003C/p>\n    \u003Cp>\n      \u003Cb>昂丹司琼：\u003C/b>主要用于预防和缓解化疗相关的恶心呕吐。禁忌症有：已知对昂丹司琼或其类似结构药物过敏者；部分遗传性糖类代谢异常患者（因片剂辅料原因）；长期QT间期延长者慎用。\n    \u003C/p>\n    \u003Cp>\n      正确做法：用药前主动告知医生过敏史及慢性疾病史。特殊人群（如儿童、老年或肝肾功能不全）需由医生调整剂量或方案。\n    \u003C/p>\n  \u003C/section>\n\n  \u003C!-- 4 药物相互作用 -->\n  \u003Csection class=\"lungca_drugguide-section\">\n    \u003Cdiv class=\"lungca_drugguide-bg lungca_drugguide-bg05\">\u003C/div>\n    \u003Ch2 class=\"lungca_drugguide-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>🔄\u003C/span> 药物相互作用要格外小心\u003C/h2>\n    \u003Cp>\n      \u003Cb>顺铂：\u003C/b>与氨基苷类抗生素（如庆大霉素）同时使用可加重肾损伤风险，应避免合并。与其他肾毒性药物联用时需密切监测血清肌酐。服用解热镇痛药也需酌情调整。\n    \u003C/p>\n    \u003Cp>\n      \u003Cb>昂丹司琼：\u003C/b>与其他5-HT\u003Csub>3\u003C/sub>受体拮抗剂合用易致心律异常，同时不建议与含或影响QT间期的药品合用。如用药包括地高辛、阿莫达非尼时应根据临床指导间隔服用。反复注射需监测心电图。\n    \u003C/p>\n    \u003Cp>\n      正确做法：每次用药主动携带全部药品明细表，让医生判断有无冲突。\n    \u003C/p>\n  \u003C/section>\n  \n  \u003C!-- 5 常见不良反应及处理方式 -->\n  \u003Csection class=\"lungca_drugguide-section\">\n    \u003Cdiv class=\"lungca_drugguide-bg lungca_drugguide-bg06\">\u003C/div>\n    \u003Ch2 class=\"lungca_drugguide-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>⚠️\u003C/span> 不良反应与紧急应对方法\u003C/h2>\n    \u003Cp>\n      \u003Cb>顺铂：\u003C/b>最常见不良反应是肾功能损伤、耳毒性（如听力下降）、恶心、呕吐及白细胞减少。临床数据显示，顺铂相关肾损伤发生率约30%。出现异常（如小便量减少、耳鸣）应立即就医。\n    \u003C/p>\n    \u003Cp>\n      \u003Cb>昂丹司琼：\u003C/b>可能引发头痛、便秘、轻微头晕及罕见过敏反应。据文献，头痛发生率约11%，便秘约6%。如出现心跳异常、全身潮红则需及时停药并咨询医生。\n    \u003C/p>\n    \u003Cp>\n      正确做法：用药期间自我观察，出现上述症状应及时告知医护人员，不可擅自停药或自行处理。\n    \u003C/p>\n  \u003C/section>\n  \n  \u003C!-- 6 漏服与过量处理办法 -->\n  \u003Csection class=\"lungca_drugguide-section\">\n    \u003Cdiv class=\"lungca_drugguide-bg lungca_drugguide-bg07\">\u003C/div>\n    \u003Ch2 class=\"lungca_drugguide-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>⛑️\u003C/span> 漏服、过量怎么办？\u003C/h2>\n    \u003Cp>\n      \u003Cb>顺铂：\u003C/b>为静脉给药，通常由医护人员管理，基本不存在漏服风险。如果疑似重复注射或剂量超标，应第一时间报告医生，由专业人员采取支持治疗措施，快速纠正水电解质紊乱。\n    \u003C/p>\n    \u003Cp>\n      \u003Cb>昂丹司琼：\u003C/b>如口服剂型漏服，正确做法是在发现后立即补服，若临近下一次服药请跳过漏服剂量。过量时可能出现严重心律异常，应立刻联系医生尽快处理。\n    \u003C/p>\n    \u003Cp>\n      科学数据支持：昂丹司琼极量使用可能引发QT延长（Saito et al., \"Safety of High-Dose Ondansetron\", 2013, Journal of Clinical Oncology）。\n    \u003C/p>\n  \u003C/section>\n  \n  \u003C!-- 7 储存条件与药品有效期 -->\n  \u003Csection class=\"lungca_drugguide-section\">\n    \u003Cdiv class=\"lungca_drugguide-bg lungca_drugguide-bg08\">\u003C/div>\n    \u003Ch2 class=\"lungca_drugguide-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>📦\u003C/span> 储存条件与药品有效期规范\u003C/h2>\n    \u003Cp>\n      \u003Cb>顺铂：\u003C/b>须在阴凉、避光、干燥环境中储存，推荐温度为2-8°C冰箱保存。避免与食品、化学品同处。开瓶后应当场使用，不留存剩余液体。\n    \u003C/p>\n    \u003Cp>\n      \u003Cb>昂丹司琼：\u003C/b>片剂需存放于通风干燥处，常温（10-25°C）即可，避免阳光直射。液体制剂用完后立即盖紧瓶盖，不要放在潮湿浴室。\n    \u003C/p>\n    \u003Cp>\n      正确做法：过期或变色药品必须丢弃，不得使用。家庭如有儿童应放在高处防止误食。\n    \u003C/p>\n  \u003C/section>\n  \n  \u003C!-- 用药案例展示（唯一性） -->\n  \u003Csection class=\"lungca_drugguide-section lungca_drugguide-casebox\">\n    \u003Cdiv class=\"lungca_drugguide-bg lungca_drugguide-bg09\">\u003C/div>\n    \u003Ch2 class=\"lungca_drugguide-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>👨‍⚕️\u003C/span> 用药案例\u003C/h2>\n    \u003Cul>\n      \u003Cli>临床使用顺铂注射剂联合昂丹司琼静脉抗呕吐，患者肾功能、血常规均监控正常，无明显不良反应。\u003C/li>\n      \u003Cli>一例中年男性接受顺铂治疗，期间提前注射昂丹司琼，成功预防了化疗相关的不适。\u003C/li>\n      \u003Cli>有患者使用昂丹司琼片剂时，因漏服后及时补服，未发生不良事件。\u003C/li>\n    \u003C/ul>\n  \u003C/section>\n  \n  \u003C!-- 参考文献（英文） -->\n  \u003Csection class=\"lungca_drugguide-section lungca_drugguide-refbox\">\n    \u003Cdiv class=\"lungca_drugguide-bg lungca_drugguide-bg10\">\u003C/div>\n    \u003Ch2 class=\"lungca_drugguide-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>📖\u003C/span> 参考文献\u003C/h2>\n    \u003Col>\n      \u003Cli>McKeage, K., Perry, C. M., & Figgitt, D. P. (2003). Cisplatin: a review of its use in the management of solid tumors. Drugs, 63(16), 2335-2357.\u003C/li>\n      \u003Cli>Saito, T., Terasaki, H., Tomita, M., et al. (2013). Safety of High-Dose Ondansetron in Preventing Chemotherapy-Induced Nausea. Journal of Clinical Oncology, 31(4), 791-795.\u003C/li>\n      \u003Cli>Roila, F., Falini, M., Del Favero, A., et al. (1991). Ondansetron in the prevention of chemotherapy-induced emesis: an overview. Cancer Investigation, 9(2), 163-177.\u003C/li>\n      \u003Cli>Moore, C., & Hainsworth, J. D. (1988). Cisplatin-induced nephrotoxicity and its prevention. Cancer Chemotherapy and Pharmacology, 21(2), 89-92.\u003C/li>\n      \u003Cli>Gan, T. J., Meyer, T., Apfel, C. C., et al. (2003). Consensus guidelines for managing postoperative nausea and vomiting. Anesthesia & Analgesia, 97(1), 62-71.\u003C/li>\u003C/ol>\u003C/section>\n\u003C/div>\n\u003Cstyle>\n.lungca_drugguide { background:#f7fafc; font-family:'Microsoft YaHei',Arial,Tahoma,sans-serif; color:#23262f; padding-bottom:48px; line-height:2; max-width:950px; margin:30px auto 0; border-radius:16px; box-shadow:0 6px 24px 0 rgba(0,0,0,0.05);}\n.lungca_drugguide-title {text-align:center; color:#183b75; font-size:2.5em; margin:35px 0 16px;}\n.lungca_drugguide-section { position:relative; padding:36px 42px 30px 42px; margin:36px auto 24px auto; border-radius:18px; background:#fff;}\n.lungca_drugguide-bg { position:absolute; left:0; top:0; width:100%; height:100%; opacity:0.09; z-index:1; border-radius:20px; pointer-events:none;}\n.lungca_drugguide-bg01 { background:linear-gradient(120deg,#cce7f8 0%,#acdbe9 90%);}\n.lungca_drugguide-bg02 { background:linear-gradient(110deg,#f8e7cc 0%,#f3e3d2 100%);}\n.lungca_drugguide-bg03 { background:linear-gradient(135deg,#e9f4d1 13%,#def5df 90%);}\n.lungca_drugguide-bg04 { background:linear-gradient(130deg,#efcfe2 14%,#e7d2e5 100%);}\n.lungca_drugguide-bg05 { background:linear-gradient(100deg,#d2eeef 0%,#b6e3df 80%);}\n.lungca_drugguide-bg06 { background:linear-gradient(120deg,#ffe6e6 0%,#f8cccc 100%);}\n.lungca_drugguide-bg07 { background:linear-gradient(135deg,#e6ecfa 0%,#c7d7ed 90%);}\n.lungca_drugguide-bg08 { background:linear-gradient(100deg,#faf9e7 0%,#f2f2d2 100%);}\n.lungca_drugguide-bg09 { background:linear-gradient(120deg,#f2e4fc 0%,#e4e1ff 100%);}\n.lungca_drugguide-bg10 { background:linear-gradient(110deg,#e6fded 12%,#c1e7cd 92%);}\n.lungca_drugguide-bg11 { background:linear-gradient(130deg,#fdd0d0 0%,#fae3e3 100%);}\n.lungca_drugguide-subtitle {position:relative;font-size:1.6em;color:#244d78;letter-spacing:1px;margin-bottom:14px;z-index:2;display:flex;align-items:center;gap:12px;font-weight:bold;}\n.lungca_drugguide-introtext {color:#493c29;font-size:1.2em;margin-bottom:10px;}\n.lungca_drugguide-refbox ol { margin:12px 0 0 22px; font-size:1.04em; line-height:1.7;}\n.lungca_drugguide-refbox { background:#eef7ef;}\n.lungca_drugguide-casebox ul { margin-left:30px; margin-top:8px;}\n.lungca_drugguide-casebox li {font-size:1.15em; margin:8px 0;}\n.lungca_drugguide-summary { background:#ffe6e6; border:2px solid #fbb0b0;}\n.lungca_drugguide-section p, .lungca_drugguide-section ul, .lungca_drugguide-section ol {position:relative;z-index:2;}\n.lungca_drugguide-section ul, .lungca_drugguide-section ol {margin-bottom:0;}\n\u003C/style>\n","\u003Cdiv class=\"lungca_drugguide\">\n  \u003Ch1 id=\"material_title\" class=\"lungca_drugguide-title\" style=\"color",415,"2025-10-09 09:24:15","顺铂, 昂丹司琼, 肺癌治疗, 化疗恶心, 药物安全使用","了解顺铂与昂丹司琼的科学使用指南，确保安全用药、预防恶心、提升肺癌化疗效率。适用于肺癌患者及医护人员的实用参考。","2025-10-21 23:30:19",2,[34],{"menuId":35,"menuName":36,"parentId":21,"orderNum":32,"path":37,"component":38,"isFrame":39,"isCache":40,"menuType":41,"visible":42,"status":21,"createDept":6,"remark":23,"createTime":43,"children":44,"columnImage":45,"columnLogo":46,"uncheckedLogo":6,"checkedLogo":6,"isHot":42,"isHome":21,"forceLogin":21,"color":47,"seoTitle":48,"seoKeywords":49,"seoDescription":50,"contentNum":6,"promotionalPoster":51,"menuFrame":7,"innerLink":7,"parentView":7,"routeName":52,"routerPath":37,"componentInfo":38},"1986713082609147906","健康科普","article","/article.html","1","0","T",1,"2025-11-07 16:31:25",[],"https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:49/d4291d16-ed1c-48dd-84c8-ec1f85980b75.png","https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:52/6fe64094-9416-442c-a66d-032fb292666a.png","#c8e6ca","健康科普助力健康中国2030:共享健康知识新理念","健康科普, 健康中国, 科普知识, 健康家庭, 性健康, 营养健康, 运动健康, 科普宣传","探索健康科普在健康中国行动中的重要角色,了解最新的健康科普创新大赛、动漫及短视频,传播健康知识,助力全民健康。","https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:56/bd33f471-6c54-4d1b-a364-b06973dbc144.png","Article","癌症肿瘤",true,{"code":9,"msg":10,"message":6,"data":56,"success":54},{"pageNo":42,"pageSize":57,"result":58,"totalSize":21},10,[],{"code":9,"msg":10,"message":6,"data":60,"success":54},{"authors":61,"appraiseDimensionScoresVos":62},[],[]]