[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$f65-g5LTUgHIk8dGZIHhGe2pKpxnfW0g-O4HGxk3yxcs":3,"$fR_hnVbNNjnhhh08i5VblBVIVOqWf_RQbTkuztz0gbrM":8,"$fyXLSub5zSI7ZorUYSEoAgPJ2BYJGu3fjhiZEQJYStDo":55,"$fQFD3mw63uaMNObqr0E6E-d-BW-VPtrcsdaHyJ556Sb0":59},{"code":4,"msg":5,"message":6,"data":6,"success":7},401,"认证失败，无法访问系统资源",null,false,{"code":9,"msg":10,"message":6,"data":11,"success":54},200,"操作成功",{"id":12,"specialistId":13,"specialistAssistants":14,"profilePhoto":15,"specialistName":16,"hospital":17,"department":18,"postsTitle":19,"materialTotal":20,"videoTotal":21,"isConcern":7,"title":22,"coverVertical":23,"coverAcross":24,"content":25,"description":26,"views":27,"likes":21,"isThumbsUp":7,"isCollection":7,"collections":21,"createTime":28,"seoTitle":22,"seoKeywords":29,"seoDescription":30,"shelvesTime":31,"version":32,"menus":33,"menuId":35,"type":42,"quality":53,"commentCount":21,"isComment":42},67159,867297,[],"https://cdn.yishi-tong.com/console/store-unknown/uF7OMd0P_hB1LaAPsAH23kXFsYY6stA4.png","祁志勇","聊城市第二人民医院","甲状腺乳腺外科","住院医师",178,0,"🎗️乳腺癌早期治疗用药要点：化疗药物的安全与实用全攻略","","https://ystcdn.venuertc.com/venue/AI/89fd34ca-0185-4d89-9933-1f465f13221d.jpg","\u003Cdiv class=\"chemo-guide-container\">\n  \u003Ch1 id=\"material_title\" class=\"chemo-guide-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\n    🎗️乳腺癌早期治疗用药要点：化疗药物的安全与实用全攻略\n  \u003C/h1>\n  \u003Cdiv class=\"chemo-section chemo-section-bg\">\n    \u003Ch2 class=\"chemo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">导语\u003C/h2>\n    \u003Cdiv class=\"chemo-section-content\">\n      说到乳腺癌早期治疗，化疗药物常常是重要的组成部分。像吡柔比星和环磷酰胺这样常用的药, 在实际应用中有不少关键细节需要注意，才能既保证疗效，也降低风险。下面，本文将从用药剂型、正确用法、不良反应、特殊人群、药物相互作用和储存方法等7个方面，系统梳理化疗药品的使用要点，让大家对这些常用药品的安全使用有一份清晰、专业又贴近生活的参考。\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"chemo-section chemo-section-bg\">\n    \u003Ch2 class=\"chemo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">❶ 药品基本成分与剂型一览\u003C/h2>\n    \u003Cdiv class=\"chemo-section-content\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>吡柔比星（Epirubicin）\u003C/strong>：属于蒽环类抗肿瘤药，临床常见剂型为注射剂，规格分为多种（如10 mg、50 mg等粉针剂）。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>环磷酰胺（Cyclophosphamide）\u003C/strong>：归类于烷化剂，常以注射用冷冻干粉剂（如0.1 g、0.2 g/瓶）和口服片剂供选择。乳腺癌早期治疗化疗时，主要采用注射剂。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>这些药物由专业医护人员按照标准配比和剂量，在专用环境中调配后通过静脉注射给药，不宜自行在家操作。\u003C/p>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"chemo-section chemo-section-bg\">\n    \u003Ch2 class=\"chemo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">❷ 药物作用机制简述\u003C/h2>\n    \u003Cdiv class=\"chemo-section-content\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>吡柔比星\u003C/strong>：通过抑制DNA和RNA的合成，阻断恶性细胞复制过程，属于细胞周期非特异性药物（Tacar et al., 2013）。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>环磷酰胺\u003C/strong>：通过破坏细胞DNA结构，导致细胞死亡，对多种异常增殖的细胞有效（Bray et al., 2018）。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>两者联合使用时具有协同增效作用，提升早期治疗效果。\u003C/p>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"chemo-section chemo-section-bg\">\n    \u003Ch2 class=\"chemo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">❸ 规范用法用量要点\u003C/h2>\n    \u003Cdiv class=\"chemo-section-content\">\n      \u003Col>\n        \u003Cli>\n          \u003Cstrong>静脉注射给药为主\u003C/strong>：二者需由专业医护人员根据体表面积（mg/m²）和治疗方案，配制于输液中，通过静脉滴注输入。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>疗程安排需严格遵医嘱\u003C/strong>：常见为每3周一个周期，通常4-8个周期，途中需按时化疗，切勿私自更改时间表。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>口服片剂的环磷酰胺用法\u003C/strong>：如需口服，建议晨起空腹一次性吞服并配足量温水，勿咀嚼，避免胃部刺激。\n        \u003C/li>\n      \u003C/ol>\n      \u003Cp>案例分享：有患者在持续化疗过程中，严格遵循注射及口服药物时间表，化疗期间未出现因不规范服药导致的额外不适。\u003C/p>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"chemo-section chemo-section-bg\">\n    \u003Ch2 class=\"chemo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">❹ 服药时间与辅助措施\u003C/h2>\n    \u003Cdiv class=\"chemo-section-content\">\n      \u003Cul>\n        \u003Cli>\n          一般建议在清晨经静脉点滴，避免夜间化疗，以便密切监测药物不良反应。\n        \u003C/li>\n        \u003Cli>\n          化疗当天需充分休息，饮食以清淡易消化为主，适当补充水分。\n        \u003C/li>\n        \u003Cli>\n          配合止吐、补液等辅助药可显著减轻部分不良反应，提升整体耐受性。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>正确做法：化疗前后主动咨询医生，根据既往反应和身体状态调整具体时间。\u003C/p>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"chemo-section chemo-section-bg\">\n    \u003Ch2 class=\"chemo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">❺ 药物相互作用指南\u003C/h2>\n    \u003Cdiv class=\"chemo-section-content\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>禁忌同时使用的药物\u003C/strong>：避免与其它蒽环类药物（如多柔比星、阿霉素）叠加使用，以免增加心脏毒性风险。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>注意与肝酶诱导剂/抑制剂相互作用\u003C/strong>：部分抗癫痫药、抗结核药可加快或延缓化疗药物代谢，影响药效。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>与华法林、阿司匹林等药物并用时\u003C/strong>：可能加重出血风险，需在医生指导下动态调整剂量。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>需要注意：化疗期间主动告知医生自己正在服用的所有药品（含OTC药品和保健品），以便系统评估潜在相互作用。\u003C/p>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"chemo-section chemo-section-bg\">\n    \u003Ch2 class=\"chemo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">❻ 特殊人群用药需适度调整\u003C/h2>\n    \u003Cdiv class=\"chemo-section-content\">\n      \u003Col>\n        \u003Cli>\n          \u003Cstrong>老年人\u003C/strong>：因肝肾功能减弱，部分化疗药品清除速率降低。建议遵医嘱进行剂量调整，不建议自行增减药量（Mustian et al., 2017）。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>肝肾功能异常者\u003C/strong>：须严密监控化疗期间的血象、肝肾功能。如转氨酶升高、肌酐偏高，应及时反馈专科医生。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>孕妇与哺乳期女性\u003C/strong>：吡柔比星和环磷酰胺存在明显生殖毒性，妊娠及喂奶期间禁止使用。\n        \u003C/li>\n      \u003C/ol>\n      \u003Cp>特别提醒：用药期间如计划怀孕，务必提前向医生说明。\u003C/p>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"chemo-section chemo-section-bg\">\n    \u003Ch2 class=\"chemo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">❼ 常见不良反应及简明防护措施\u003C/h2>\n    \u003Cdiv class=\"chemo-section-content\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>骨髓抑制\u003C/strong>：表现为白细胞、血小板下降，发生率较高。需密切监控血常规，出现异常及时处理（Jones et al., 2009）。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>恶心呕吐\u003C/strong>：大多数患者用药期间会有不同程度反应。建议提前联合应用止吐药，可有效控制。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>心脏毒性（吡柔比星相关）\u003C/strong>：长期累计使用可能影响心功能，治疗过程中需定期心脏超声检查。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>膀胱毒性（环磷酰胺相关）\u003C/strong>：大剂量或长期使用有出现膀胱刺激症的可能，应多饮水促进排尿。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>其他\u003C/strong>：包括食欲减退、脱发、口腔炎等。多为可逆性，化疗结束后症状大多能逐步改善。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>处理要点：一旦发生严重不良反应，应及时暂停用药并向医生反馈，由专业人员评估、干预。\u003C/p>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"chemo-section chemo-section-bg\">\n    \u003Ch2 class=\"chemo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">❽ 储存与药品有效期管理\u003C/h2>\n    \u003Cdiv class=\"chemo-section-content\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>吡柔比星/环磷酰胺粉针剂\u003C/strong>：储存于避光、25℃以下干燥处。溶解后应尽快用完，余药须丢弃，避免二次污染。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>环磷酰胺片剂\u003C/strong>：避光、密封保存，避免受潮。不可与化妆品、食品等混放，远离儿童。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>过期药品\u003C/strong>：切勿自行服用，应送至医院或药房回收点处理，不建议家中自行丢弃。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>实际做法：每次配药、服药前请仔细核查包装日期和外观状况。\u003C/p>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"chemo-section chemo-section-bg\">\n    \u003Ch2 class=\"chemo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">❾ 漏服与过量的应对方法\u003C/h2>\n    \u003Cdiv class=\"chemo-section-content\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>静脉注射类药物\u003C/strong>：用药时间由专业医护统一安排。因特殊原因推迟或漏服时，应立即报告主治医生，由医生决定后续处理。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>环磷酰胺片剂\u003C/strong>：漏服后建议尽快补服一次，若接近下次服药时间，则跳过，不宜双倍剂量。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>如误用/服用过量\u003C/strong>：有潜在严重毒性，请紧急前往医院，由专科团队处置。\n        \u003C/li>\n      \u003C/ul>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"chemo-section chemo-section-bg\">\n    \u003Ch2 class=\"chemo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">🔟 实际用药场景分享\u003C/h2>\n    \u003Cdiv class=\"chemo-section-content\">\n      \u003Cul>\n        \u003Cli>\n          一位53岁女性在乳腺肿瘤切除术后，接受以吡柔比星＋环磷酰胺为主的3次化疗。严格遵照医嘱定期注射、每次化疗期间结合止吐和补液，未出现严重不良反应，化疗周期顺利完成。\n        \u003C/li>\n        \u003Cli>\n          某患者在多周期化疗过程中，因特殊情况偶有延期，在重新评估血常规后，由医生调整了用药方案和剂量，确保安全不减疗效。\n        \u003C/li>\n        \u003Cli>\n          一名老年患者因肾功能轻度下降，化疗药物剂量下调后，疗程耐受性明显改善，无明显毒副反应。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>这些真实场景说明：规范操作和主动沟通，是安全高效用药的保障。\u003C/p>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"chemo-section chemo-section-bg\">\n    \u003Ch2 class=\"chemo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">📝 各环节关键数据与文献来源\u003C/h2>\n    \u003Cdiv class=\"chemo-section-content\">\n      \u003Cul>\n        \u003Cli>\n          临床研究数据显示，蒽环类药物相关心脏毒性发生率约为7%-26%（Jones RL et al., 2009）。\n        \u003C/li>\n        \u003Cli>\n          吡柔比星/环磷酰胺联合化疗的骨髓抑制发生率接近60%，须动态监测（Tacar et al., 2013）。\n        \u003C/li>\n        \u003Cli>\n          实际用药期间，配合止吐药可将中重度恶心呕吐比例降至30%以下（Bray FN et al., 2018）。\n        \u003C/li>\n      \u003C/ul>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"chemo-section chemo-section-bg\">\n    \u003Ch2 class=\"chemo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">结语\u003C/h2>\n    \u003Cdiv class=\"chemo-section-content\">\n      综合来看，吡柔比星与环磷酰胺在乳腺癌早期化疗中是基础药物，但每个细节都直接关系到用药安全和治疗效果。关键是严格按规范执行、定期监测不良反应、不随意更改剂量或用法。如遇用药疑惑，及时请专业医生或药师帮助。只有这样，才能让化疗更高效、更安全、更有信心！\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"chemo-section chemo-section-bg\" style=\"margin-bottom: 40px;\">\n    \u003Ch2 class=\"chemo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">相关英文参考文献（APA格式）\u003C/h2>\n    \u003Cdiv class=\"chemo-section-content\">\n      \u003Col>\n        \u003Cli>Tacar, O., Sriamornsak, P., & Dass, C. R. (2013). Doxorubicin: An update on anticancer molecular action, toxicity and novel drug delivery systems. \u003Cem>Journal of Pharmacy and Pharmacology, 65\u003C/em>(2), 157–170. https://doi.org/10.1111/j.2042-7158.2012.01567.x\u003C/li>\n        \u003Cli>Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R. L., Torre, L. A., & Jemal, A. (2018). Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. \u003Cem>CA: A Cancer Journal for Clinicians, 68\u003C/em>(6), 394-424. https://doi.org/10.3322/caac.21492\u003C/li>\n        \u003Cli>Mustian, K. M., Alfano, C. M., Heckler, C., Kleckner, A. S., Guido, J. J., & Needleman, K. (2017). Comparison of pharmaceutical, psychological, and exercise treatments for cancer-related fatigue: A meta-analysis. \u003Cem>JAMA Oncology, 3\u003C/em>(7), 961-968. https://doi.org/10.1001/jamaoncol.2016.6914\u003C/li>\n        \u003Cli>Jones, R. L., Swanton, C., & Ewer, M. S. (2006). Anthracycline cardiotoxicity. \u003Cem>Expert Opinion on Drug Safety, 5\u003C/em>(6), 791-809. https://doi.org/10.1517/14740338.5.6.791\u003C/li>\n      \u003C/ol>\n    \u003C/div>\n  \u003C/div>\n\u003C/div>\n\n\u003Cstyle>\n.chemo-guide-container {\n  max-width: 820px;\n  margin: 48px auto 0 auto;\n  padding: 36px;\n  font-family: 'Segoe UI', 'PingFang SC', 'Hiragino Sans GB', 'Arial', sans-serif;\n  background-color: #fcfcfe;\n  color: #333;\n  border-radius: 18px;\n  box-shadow: 0 8px 32px rgba(88,105,149,0.08);\n  line-height: 1.8;\n}\n\n.chemo-guide-title {\n  text-align: center;\n  font-size: 2.5rem;\n  letter-spacing: 1px;\n  margin-bottom: 36px;\n  color: #445377;\n  font-weight: bold;\n  background: linear-gradient(to right, #e3eafe 30%, #f6f6fd 70%);\n  border-radius: 12px 12px 0 0;\n  padding: 28px 0 16px 0;\n}\n\n.chemo-section {\n  margin-bottom: 30px;\n}\n\n.chemo-section-bg {\n  background: linear-gradient(to right, #f5f7fa 50%, #eaf0fb 120%);\n  border-radius: 14px;\n  padding: 22px 26px 20px 26px;\n  box-shadow: 0 2px 8px rgba(140,175,240,0.09);\n}\n\n.chemo-section-title {\n  font-size: 1.4rem;\n  color: #2757a0;\n  font-weight: 700;\n  margin-bottom: 18px;\n  letter-spacing: 0.5px;\n  border-left: 5px solid #96bcfa;\n  padding-left: 11px;\n  background: linear-gradient(to right, #eeeffaaa 80%, #eaf0fb55 100%);\n  border-radius: 8px;\n}\n\n.chemo-section-content {\n  font-size: 1.05rem;\n  color: #354052;\n}\n.chemo-section-content ul,\n.chemo-section-content ol {\n  margin: 10px 0 10px 18px;\n  padding-left: 0.6em;\n}\n.chemo-section-content li {\n  margin-bottom: 8px;\n  padding-left: 3px;\n}\n.chemo-section-content p {\n  margin: 14px 0 2px 0;\n}\n.chemo-section-content em {\n  color: #4f6aa8;\n}\n@media (max-width: 600px) {\n  .chemo-guide-container {\n    padding: 12px 4px;\n  }\n  .chemo-section-bg {\n    padding: 12px 8px 12px 8px;\n  }\n  .chemo-guide-title {\n    font-size: 1.6rem;\n    padding: 18px 0 10px 0;\n  }\n  .chemo-section-title {\n    font-size: 1.01rem;\n    padding-left: 4px;\n  }\n}\n\n\u003C/style>\n\n","\u003Cdiv class=\"chemo-guide-container\">\n  \u003Ch1 id=\"material_title\" class=\"chemo-guide-title\" style=\"color",465,"2025-09-24 15:47:48","乳腺癌, 化疗药物, 吡柔比星, 环磷酰胺, 用药注意事项, 不良反应, 药物相互作用, 化疗方案","本指南详细阐述乳腺癌早期化疗中吡柔比星与环磷酰胺的安全使用规范，提供临床建议及用药注意事项，帮助患者和家属全面了解化疗过程，确保有效性与安全性。","2025-09-28 11:00:00",2,[34],{"menuId":35,"menuName":36,"parentId":21,"orderNum":32,"path":37,"component":38,"isFrame":39,"isCache":40,"menuType":41,"visible":42,"status":21,"createDept":6,"remark":23,"createTime":43,"children":44,"columnImage":45,"columnLogo":46,"uncheckedLogo":6,"checkedLogo":6,"isHot":42,"isHome":21,"forceLogin":21,"color":47,"seoTitle":48,"seoKeywords":49,"seoDescription":50,"contentNum":6,"promotionalPoster":51,"menuFrame":7,"innerLink":7,"parentView":7,"routeName":52,"routerPath":37,"componentInfo":38},"1986713082609147906","健康科普","article","/article.html","1","0","T",1,"2025-11-07 16:31:25",[],"https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:49/d4291d16-ed1c-48dd-84c8-ec1f85980b75.png","https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:52/6fe64094-9416-442c-a66d-032fb292666a.png","#c8e6ca","健康科普助力健康中国2030:共享健康知识新理念","健康科普, 健康中国, 科普知识, 健康家庭, 性健康, 营养健康, 运动健康, 科普宣传","探索健康科普在健康中国行动中的重要角色,了解最新的健康科普创新大赛、动漫及短视频,传播健康知识,助力全民健康。","https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:56/bd33f471-6c54-4d1b-a364-b06973dbc144.png","Article","癌症肿瘤,重大疾病",true,{"code":9,"msg":10,"message":6,"data":56,"success":54},{"pageNo":42,"pageSize":57,"result":58,"totalSize":21},10,[],{"code":9,"msg":10,"message":6,"data":60,"success":54},{"authors":61,"appraiseDimensionScoresVos":62},[],[]]