[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$f65-g5LTUgHIk8dGZIHhGe2pKpxnfW0g-O4HGxk3yxcs":3,"$f029ZLW3OS7_SmbcGujDNuIbVPklkeOs1fTiZDXlvm9k":8,"$fyXVxBUJzkY6fWda6pRo21RO3mq42GOWBNdNfkSCHzLA":55,"$ffN-6aLtcx33u9oXsbKxVQfg7apAjGbJdsQ2cwYF_cZA":59},{"code":4,"msg":5,"message":6,"data":6,"success":7},401,"认证失败，无法访问系统资源",null,false,{"code":9,"msg":10,"message":6,"data":11,"success":54},200,"操作成功",{"id":12,"specialistId":13,"specialistAssistants":14,"profilePhoto":15,"specialistName":16,"hospital":17,"department":18,"postsTitle":19,"materialTotal":20,"videoTotal":21,"isConcern":7,"title":22,"coverVertical":23,"coverAcross":24,"content":25,"description":26,"views":27,"likes":21,"isThumbsUp":7,"isCollection":7,"collections":21,"createTime":28,"seoTitle":22,"seoKeywords":29,"seoDescription":30,"shelvesTime":31,"version":32,"menus":33,"menuId":35,"type":42,"quality":53,"commentCount":21,"isComment":42},66544,870555,[],"https://cdn.haohuanjiao.com/learnMaterial/ystApp//k2lpdTYQaoQUNX2k8n245YQUoXZuo0z1.png","吴旻骅","宁波市医疗中心李惠利医院","甲状腺乳腺外科","副主任医师",3,0,"关于乳腺癌，你需要了解的关键知识","","https://ystcdn.venuertc.com/venue/AI/641a8ca4-bbed-4c76-a762-7100922202b5.jpg","\u003Cdiv class=\"custom-breast-cancer-container\">\n  \u003Ch2 id=\"material_title\" class=\"custom-breast-cancer-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">关于乳腺癌，你需要了解的关键知识\u003C/h2>\n  \n  \u003C!-- 开头段落 -->\n  \u003Cdiv class=\"custom-breast-cancer-intro\">\n    在小区广场、家人的餐桌上，乳腺癌常常被提及，但很多人对它的了解仍充满误区。其实，一些身体的细微变化，生活上的小习惯，都可能与乳腺健康息息相关。一起聊聊乳腺癌，从陌生的名词变成咱们能看懂、用得上的健康常识。\n  \u003C/div>\n  \n  \u003C!-- 01 乳腺癌的基本概念 -->\n  \u003Csection class=\"custom-breast-cancer-section custom-breast-cancer-bg1\">\n    \u003Ch2 class=\"custom-breast-cancer-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan class=\"emoji\">🔬\u003C/span> 01 乳腺癌的基本概念\u003C/h2>\n    \u003Cp>\n      乳腺癌，说起来并不神秘，其实是一种起源于乳腺腺体细胞的恶性肿瘤。乳腺癌发生时，这些本该“安分守己”的乳腺细胞突然开始异常生长、繁殖，不受身体调控，最后挤成一团形成肿块。如果没有及时发现，这些异常细胞可能突破乳腺界限，进入淋巴或血液，在身体其他部位“安营扎寨”。\n    \u003C/p>\n    \u003Cp>\n      2022年，全世界一共有230万名女性新发乳腺癌，乳腺癌成为许多国家女性最常见的癌症\u003Csup>[1]\u003C/sup>。更直白一点，每12名城市女性中，可能就有1人在一生中遇到乳腺癌的挑战。不过，乳腺癌早期发现后，治愈率其实很高，这也是为什么更早了解它非常有必要。\n    \u003C/p>\n    \u003Cp>\n      比起一上来就谈“绝症”，把乳腺癌理解为身体里的“不速之客”，及时发现和应对，比担心更有价值。\n    \u003C/p>\n  \u003C/section>\n  \n  \u003C!-- 02 乳腺癌的早期症状有哪些？ -->\n  \u003Csection class=\"custom-breast-cancer-section custom-breast-cancer-bg2\">\n    \u003Ch2 class=\"custom-breast-cancer-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan class=\"emoji\">👀\u003C/span> 02 乳腺癌的早期症状有哪些？\u003C/h2>\n    \u003Cdiv class=\"custom-breast-cancer-point\">\n      \u003Cspan class=\"custom-breast-cancer-point-title\">1. 乳房肿块（常见但容易忽略）\u003C/span>\n      \u003Cp>\n        身体一般没大毛病，只是偶尔摸到乳房某个地方有一颗“豆豆”状的硬结，大部分没有明显疼痛。有的人在洗澡、换衣服时发现，有的人是体检时偶然被提出来。比如一位69岁的女性朋友，右乳发现小肿块两年多，刚开始没在意，后来才去医院检查，发现是早期乳腺癌。她的经历说明，很多乳腺癌在初期只是轻微硬结或变厚，没有其他特别感觉。\n      \u003C/p>\n    \u003C/div>\n    \u003Cdiv class=\"custom-breast-cancer-point\">\n      \u003Cspan class=\"custom-breast-cancer-point-title\">2. 乳房皮肤凹陷或褶皱\u003C/span>\n      \u003Cp>\n        日常穿衣或洗澡时，突然发现乳房轮廓有些变化，比如皮肤有点内陷，摸起来像果皮凹进去一样。这种时候虽然一般不疼，但这种小变化最好还是留心一下。皮肤凹陷，有时候是肿瘤拉扯乳腺组织的信号。\n      \u003C/p>\n    \u003C/div>\n    \u003Cdiv class=\"custom-breast-cancer-point\">\n      \u003Cspan class=\"custom-breast-cancer-point-title\">3. 乳头分泌物，尤其是血性液体\u003C/span>\n      \u003Cp>\n        平时没喂奶，却突然发现乳头有透明或带血的液体流出来。尤其是挤压时出现，且只有单侧乳房，“警报”级别要拉高点。偶尔一滴并不少见，但如果持续、有颜色改变，最好让医生帮忙看一看。\n      \u003C/p>\n    \u003C/div>\n    \u003Cdiv class=\"custom-breast-cancer-point\">\n      \u003Cspan class=\"custom-breast-cancer-point-title\">4. 乳房大小、形状、外观变化\u003C/span>\n      \u003Cp>\n        某些女性发现一侧乳房有变大、变硬、表面不光滑，这些都是乳腺癌可能出现的调整信号。这类变化，建议用镜面观察比单纯用手触摸更容易发现。\n      \u003C/p>\n    \u003C/div>\n    \u003Cp>\n      需要提醒，有些良性乳腺疾病也有类似表现，不要因为发现肿块就陷入恐慌。如果有变化，建议找乳腺专科医生科学排查。\n    \u003C/p>\n  \u003C/section>\n  \n  \u003C!-- 03 乳腺癌的发生机制是什么？ -->\n  \u003Csection class=\"custom-breast-cancer-section custom-breast-cancer-bg3\">\n    \u003Ch2 class=\"custom-breast-cancer-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan class=\"emoji\">🧬\u003C/span> 03 乳腺癌的发生机制是什么？\u003C/h2>\n    \u003Cul class=\"custom-breast-cancer-mechanism-list\">\n      \u003Cli>\n        \u003Cspan class=\"custom-breast-cancer-mechanism-point\">遗传因素\u003C/span>\n        \u003Cdiv>家族里有直系亲属（母亲、姐妹）曾患乳腺癌，风险会增加。特别是在某些重要基因比如BRCA1、BRCA2有变化时，乳腺细胞调控能力受到影响，出现异常增殖的概率增加。《New England Journal of Medicine》曾指出，携带BRCA1/2基因突变的女性，毕生患乳腺癌风险高达45%-70%\u003Csup>[2]\u003C/sup>。\u003C/div>\n      \u003C/li>\n      \u003Cli>\n        \u003Cspan class=\"custom-breast-cancer-mechanism-point\">激素影响\u003C/span>\n        \u003Cdiv>体内雌激素、孕激素长期水平偏高，会刺激乳腺细胞频繁分裂。有研究显示，初潮早、绝经晚、未生育或晚生育、长期口服激素药物的女性，患乳腺癌概率略有提升。\u003C/div>\n      \u003C/li>\n      \u003Cli>\n        \u003Cspan class=\"custom-breast-cancer-mechanism-point\">生活方式与环境\u003C/span>\n        \u003Cdiv>肥胖、缺乏运动、经常熬夜、高脂饮食、酒精摄入较多，也可能让乳腺细胞长期处于应激状态。长期处于污染或辐射环境，也会让乳腺细胞变得不稳定。一些国家调查显示，饮酒女性乳腺癌风险比不喝酒女性高20%左右\u003Csup>[3]\u003C/sup>。\u003C/div>\n      \u003C/li>\n      \u003Cli>\n        \u003Cspan class=\"custom-breast-cancer-mechanism-point\">年龄因素\u003C/span>\n        \u003Cdiv>乳腺癌虽然年轻人也有发生，不过50岁以上女性风险明显增加。年龄越大，乳腺细胞修复能力逐渐下降，异常增殖的概率也会上升。\u003C/div>\n      \u003C/li>\n      \u003Cli>\n        \u003Cspan class=\"custom-breast-cancer-mechanism-point\">大多数患者没有明确高危因素\u003C/span>\n        \u003Cdiv>值得一说，约一半乳腺癌病例在除了性别和年龄外查不到特定危险原因，这说明乳腺癌的发生既有遗传，也有环境和偶然性混合影响。\u003C/div>\n      \u003C/li>\n    \u003C/ul>\n  \u003C/section>\n  \n  \u003C!-- 04 乳腺癌的诊断步骤是什么？ -->\n  \u003Csection class=\"custom-breast-cancer-section custom-breast-cancer-bg4\">\n    \u003Ch2 class=\"custom-breast-cancer-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan class=\"emoji\">🩺\u003C/span> 04 乳腺癌的诊断步骤是什么？\u003C/h2>\n    \u003Cp>\n      乳腺癌的诊断是一个循序渐进的过程。简单来说，从发现异常到确诊，大体有三步：\n    \u003C/p>\n    \u003Cdiv class=\"custom-breast-cancer-diagnosis\">\n      \u003Cdiv class=\"custom-breast-cancer-diagnosis-step\">\n        \u003Cspan class=\"step-title\">① 影像学检查\u003C/span>\n        \u003Cp>主要有乳腺X线（常称钼靶）、超声、MRI。这些方法可以帮助医生看清楚乳腺里的小结节、钙化点或者结构异常，是筛查和初步判断的好帮手。例如，前述69岁患者的乳腺超声显示4C类结节，意味着有较高恶性概率，需进一步检查。\u003C/p>\n      \u003C/div>\n      \u003Cdiv class=\"custom-breast-cancer-diagnosis-step\">\n        \u003Cspan class=\"step-title\">② 组织活检\u003C/span>\n        \u003Cp>只有通过穿刺或手术取一块可疑组织，送病理分析，才能最终确定是不是癌症。病理报告还会告诉医生癌细胞的类型、分级，为后续治疗做参考。\u003C/p>\n      \u003C/div>\n      \u003Cdiv class=\"custom-breast-cancer-diagnosis-step\">\n        \u003Cspan class=\"step-title\">③ 进一步分期检查\u003C/span>\n        \u003Cp>如果诊断为乳腺癌，还需做胸腹盆腔CT、骨扫描等，评估癌症是否已经扩散。\u003C/p>\n      \u003C/div>\n    \u003C/div>\n    \u003Cp>\n      总结来说，身体发现乳腺异常变化，及时找有资质的医院按流程检查、确认，能让治疗准备更充分。当检查提示BI-RADS 4C及以上，建议尽快接受活检，不要犹豫拖延。\n    \u003C/p>\n  \u003C/section>\n  \n  \u003C!-- 05 乳腺癌的主要治疗方法 -->\n  \u003Csection class=\"custom-breast-cancer-section custom-breast-cancer-bg5\">\n    \u003Ch2 class=\"custom-breast-cancer-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan class=\"emoji\">💉\u003C/span> 05 乳腺癌的主要治疗方法\u003C/h2>\n    \u003Cul class=\"custom-breast-cancer-treatment-list\">\n      \u003Cli>\n        \u003Cspan class=\"custom-breast-cancer-treatment-title\">手术切除（“局部修复”）\u003C/span>\n        \u003Cdiv>常见方式有保乳手术和乳房全切手术，早期小肿瘤有时可以保住乳房。比如前文的患者，接受了保乳根治术和淋巴结清扫。切除范围是否足够，医生会通过“切缘”来判断，如果没有癌细胞残留，说明暂时安全。\u003C/div>\n      \u003C/li>\n      \u003Cli>\n        \u003Cspan class=\"custom-breast-cancer-treatment-title\">放疗\u003C/span>\n        \u003Cdiv>手术后，为了杀死局部残留的微小癌细胞，减少复发不少，医生会建议放疗。尤其是保乳后的女性，辅助放疗极为重要。\u003C/div>\n      \u003C/li>\n      \u003Cli>\n        \u003Cspan class=\"custom-breast-cancer-treatment-title\">化疗\u003C/span>\n        \u003Cdiv>针对某些高风险类型，化疗药物可控制全身已扩散或潜在扩散的癌细胞。化疗一般分为术前（新辅助）和术后（辅助）两种。\u003C/div>\n      \u003C/li>\n      \u003Cli>\n        \u003Cspan class=\"custom-breast-cancer-treatment-title\">内分泌疗法\u003C/span>\n        \u003Cdiv>如果病理提示肿瘤细胞对激素敏感（如ER、PR阳性），那么通过药物干预雌激素和孕激素的作用，可以有效降低复发率。口服药物，一般疗程长，副作用相对化疗较轻。\u003C/div>\n      \u003C/li>\n      \u003Cli>\n        \u003Cspan class=\"custom-breast-cancer-treatment-title\">靶向治疗\u003C/span>\n        \u003Cdiv>特殊类型如Her2阳性乳腺癌，有专门“定位打击”的靶向药物，副作用较化疗小但成本较高。\u003C/div>\n      \u003C/li>\n      \u003Cli>\n        \u003Cspan class=\"custom-breast-cancer-treatment-title\">其他支持治疗\u003C/span>\n        \u003Cdiv>针对骨转移、疼痛等症状，可以用止痛药、双膦酸盐等药物帮助缓解，提升生活质量。\u003C/div>\n      \u003C/li>\n    \u003C/ul>\n    \u003Cp>\n      不同的乳腺癌类型、分期、个人身体情况，治疗组合可能不同。治疗方案的个性化越来越被重视，多学科团队（如肿瘤科、营养师、康复团队）共同参与，对康复有很大帮助\u003Csup>[4]\u003C/sup>。\n    \u003C/p>\n  \u003C/section>\n  \n  \u003C!-- 06 如何有效管理自己的乳腺健康？ -->\n  \u003Csection class=\"custom-breast-cancer-section custom-breast-cancer-bg6\">\n    \u003Ch2 class=\"custom-breast-cancer-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan class=\"emoji\">🌱\u003C/span> 06 如何有效管理自己的乳腺健康？\u003C/h2>\n    \u003Cul class=\"custom-breast-cancer-prevention-list\">\n      \u003Cli>\n        \u003Cspan class=\"custom-breast-cancer-prevention-title\">1. 粗粮蔬果搭配，乳腺“守护神”\u003C/span>\n        \u003Cdiv>\n          新鲜蔬菜中的叶酸、维生素C有助于乳腺细胞稳定分裂，同时补充五谷杂粮中的膳食纤维，帮助调节体内激素，减少乳腺细胞异常增殖的机会。\u003Cbr>\n          \u003Cstrong>食用建议：\u003C/strong>每天保证有三种绿叶蔬菜和两种以上杂粮入餐，颜色鲜艳、当季新鲜优先。\n        \u003C/div>\n      \u003C/li>\n      \u003Cli>\n        \u003Cspan class=\"custom-breast-cancer-prevention-title\">2. 坚果和豆类，给乳腺细胞添“能量”\u003C/span>\n        \u003Cdiv>\n          豆制品富含植物雌激素，可以调节激素平衡，防止激素波动让乳腺细胞变得不安定。坚果含有优质脂肪酸，有利于抗氧化和减轻炎症。\u003Cbr>\n          \u003Cstrong>食用建议：\u003C/strong>每周吃2-3次豆腐、豆浆、扁豆，适量坚果（比如杏仁、核桃）每天一小把。\n        \u003C/div>\n      \u003C/li>\n      \u003Cli>\n        \u003Cspan class=\"custom-breast-cancer-prevention-title\">3. 保持适量运动，乳腺“自检小动作”不忽视\u003C/span>\n        \u003Cdiv>\n          规律运动能促进激素代谢，让乳腺组织“流通”更顺畅。有研究显示，适度锻炼可以减少乳腺癌风险达20%\u003Csup>[5]\u003C/sup>。\u003Cbr>\n          \u003Cstrong>建议：\u003C/strong>每周快走、游泳、骑车等中等强度运动不少于三次，每次数十分钟足矣。\n        \u003C/div>\n      \u003C/li>\n      \u003Cli>\n        \u003Cspan class=\"custom-breast-cancer-prevention-title\">4. 自检、体检固定安排\u003C/span>\n        \u003Cdiv>\n          自己检查乳腺，最好选在每月例假结束后的3-7天，用指腹轻轻环绕乳房检查有无新肿块或不适。40岁以后，建议每1-2年做一次乳腺X线或超声检查。\n        \u003C/div>\n      \u003C/li>\n      \u003Cli>\n        \u003Cspan class=\"custom-breast-cancer-prevention-title\">5. 出现异常变化，及时就医\u003C/span>\n        \u003Cdiv>\n          如果发现乳房持续肿块、乳头异常分泌物、皮肤凹陷等现象，最好到正规医院乳腺专科做全面评估，尽量避免拖延。\n        \u003C/div>\n      \u003C/li>\n      \u003Cli>\n        \u003Cspan class=\"custom-breast-cancer-prevention-title\">6. 身心调整，减少精神压力\u003C/span>\n        \u003Cdiv>\n          长期压力、持续焦虑会影响内分泌，间接增加乳腺癌相关风险。可以通过散步、冥想、听音乐、聊天等方式调节心情，给身体和乳腺一点“喘息空间”。\n        \u003C/div>\n      \u003C/li>\n    \u003C/ul>\n    \u003Cp>\n      每个人的乳腺健康状况不同，最重要的是养成定期自查、规律作息、饮食均衡的习惯。如有任何疑惑，能勇敢求助医生，就是对自己最好的照顾。\n    \u003C/p>\n  \u003C/section>\n  \n  \u003C!-- 参考文献 -->\n  \u003Csection class=\"custom-breast-cancer-section custom-breast-cancer-bg7\">\n    \u003Ch2 class=\"custom-breast-cancer-ref-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan class=\"emoji\">📚\u003C/span> 主要参考文献（APA引用格式）\u003C/h2>\n    \u003Cdiv class=\"custom-breast-cancer-ref-list\">\n      \u003Col>\n        \u003Cli>World Health Organization. (2024). \u003Ci>Breast cancer: Key facts\u003C/i>. Retrieved from https://www.who.int/news-room/fact-sheets/detail/breast-cancer\u003C/li>\n        \u003Cli>King, M.-C., Marks, J. H., & Mandell, J. B. (2003). Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2. \u003Ci>New England Journal of Medicine, 345\u003C/i>(23), 1687-1697. https://doi.org/10.1056/NEJMoa021108\u003C/li>\n        \u003Cli>Scoccianti, C., et al. (2014). European Code against Cancer 4th Edition: Alcohol drinking and cancer. \u003Ci>Cancer Epidemiology\u003C/i>, \u003Cb>38\u003C/b>(Suppl 1), S62-S74. https://doi.org/10.1016/j.canep.2014.07.008\u003C/li>\n        \u003Cli>Cardoso, F., et al. (2017). Early breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. \u003Ci>Annals of Oncology, 28\u003C/i>(4), iv119–iv138. https://doi.org/10.1093/annonc/mdx692\u003C/li>\n        \u003Cli>Friedenreich, C. M., Neilson, H. K., & Lynch, B. M. (2010). State of the epidemiological evidence on physical activity and cancer prevention. \u003Ci>European Journal of Cancer\u003C/i>, \u003Cb>46\u003C/b>(14), 2593–2604. https://doi.org/10.1016/j.ejca.2010.07.028\u003C/li>\n      \u003C/ol>\n    \u003C/div>\n  \u003C/section>\n\u003C/div>\n\n\u003Cstyle>\n.custom-breast-cancer-container {\n  max-width: 790px;\n  margin: 38px auto;\n  background: #fffcf8;\n  border-radius: 14px;\n  padding: 34px 28px 44px 28px;\n  font-family: \"Helvetica Neue\", Helvetica, Arial, \"PingFang SC\", \"Microsoft YaHei\", sans-serif;\n  line-height: 2;\n  color: #242424;\n  box-shadow: 0 7px 38px 0 rgba(185, 185, 145, 0.10);\n  font-size: 18px;\n}\n.custom-breast-cancer-title {\n  font-size: 32px;\n  color: #963a38;\n  letter-spacing: 2px;\n  margin-bottom: 38px;\n  text-align: center;\n  font-weight: 600;\n  text-shadow: 0 2px 12px rgba(235,140,152,0.08);\n}\n.custom-breast-cancer-intro {\n  font-size: 21px;\n  line-height: 2.1;\n  margin: 0 0 30px 0;\n  color: #714748;\n  padding: 18px 22px;\n  border-left: 6px solid #f4b1ba;\n  background: linear-gradient(to right,#fdecea 50%,#ffffff 100%);\n}\n.custom-breast-cancer-section {\n  margin: 48px 0 16px 0;\n  border-radius: 12px;\n  padding: 28px 30px 24px 30px;\n  position: relative;\n  box-shadow: 0 4px 18px 0 rgba(220,114,96,.06);\n  background: #fffaf7;\n}\n.custom-breast-cancer-bg1 {\n  background: linear-gradient(100deg, #fde7d8 0%, #fff7ec 110%);\n}\n.custom-breast-cancer-bg2 {\n  background: linear-gradient(100deg, #f8eaed 0%, #ffe6ed 120%);\n}\n.custom-breast-cancer-bg3 {\n  background: linear-gradient(100deg, #e7f2f4 0%, #f6f9fa 120%);\n}\n.custom-breast-cancer-bg4 {\n  background: linear-gradient(100deg, #ece4fe 0%, #efeff9 120%);\n}\n.custom-breast-cancer-bg5 {\n  background: linear-gradient(100deg, #faeddc 0%, #fff5e7 120%);\n}\n.custom-breast-cancer-bg6 {\n  background: linear-gradient(100deg, #e3f3e8 0%, #f5faf5 120%);\n}\n.custom-breast-cancer-bg7 {\n  background: linear-gradient(100deg, #edf0fe 0%, #f2f6fc 120%);\n  margin-bottom: 36px;\n}\n.custom-breast-cancer-subtitle {\n  font-size: 26px;\n  color: #824b3b;\n  margin-bottom: 24px;\n  font-weight: 700;\n  letter-spacing: 1px;\n  position: relative;\n}\n.custom-breast-cancer-subtitle .emoji {\n  font-size: 1.3em;\n  margin-right: 8px;\n  vertical-align: middle;\n}\n.custom-breast-cancer-point {\n  margin-bottom: 20px;\n  padding-left: 6px;\n}\n.custom-breast-cancer-point-title {\n  font-size: 19px;\n  font-weight: 600;\n  color: #be3262;\n  margin-bottom: 2px;\n  display: inline-block;\n}\n.custom-breast-cancer-mechanism-list {\n  margin: 0 0 0 4px;\n  padding: 0 0 0 12px;\n  list-style-type: disc;\n}\n.custom-breast-cancer-mechanism-point {\n  font-weight: 600;\n  color: #4c6986;\n}\n.custom-breast-cancer-diagnosis {\n  margin-top: 10px;\n}\n.custom-breast-cancer-diagnosis-step {\n  margin-bottom: 14px;\n  padding-left: 8px;\n}\n.custom-breast-cancer-diagnosis-step .step-title {\n  font-weight: 600;\n  color: #6350ab;\n  font-size: 18px;\n  margin-right: 4px;\n}\n.custom-breast-cancer-treatment-list {\n  margin: 0 0 0 2px;\n  padding: 0 0 0 18px;\n  list-style-type: square;\n}\n.custom-breast-cancer-treatment-title {\n  color: #cd7762;\n  font-weight: 600;\n  font-size: 18px;\n}\n.custom-breast-cancer-prevention-list {\n  list-style: disc;\n  margin-left: 10px;\n  margin-bottom: 16px;\n}\n.custom-breast-cancer-prevention-title {\n  font-size: 18px;\n  color: #478c53;\n  font-weight: bold;\n}\n.custom-breast-cancer-ref-title {\n  font-size: 22px;\n  color: #3f4c7d;\n  font-weight: 700;\n  margin-bottom: 22px;\n  letter-spacing: 1px;\n}\n.custom-breast-cancer-ref-list {\n  font-size: 15px;\n  margin-left: 16px;\n  color: #666985;\n  line-height: 1.6;\n}\nsup {\n  color: #ae3a78;\n  font-size: 13px;\n  font-family: inherit;\n  vertical-align: super;\n}\n@media (max-width: 900px) {\n  .custom-breast-cancer-container {\n    padding: 10px 4vw 18px 4vw;\n  }\n  .custom-breast-cancer-section {\n    padding: 11px 10px 16px 10px;\n  }\n}\n@media (max-width: 580px) {\n  .custom-breast-cancer-title { font-size: 1.4em; 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