[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$f65-g5LTUgHIk8dGZIHhGe2pKpxnfW0g-O4HGxk3yxcs":3,"$fjOIsJRU_LZ3OXfie_1a3nzAr5ClySGug1JSXngJ0-48":8,"$fC6lcZNM077gASw_HuVI9OuEEk0NtKATjWonLyJ-hCZE":55,"$f581_mhPS7e6vZwL-JoK2euPYZ1xqZTaj6GTKpFiJ_xs":59},{"code":4,"msg":5,"message":6,"data":6,"success":7},401,"认证失败，无法访问系统资源",null,false,{"code":9,"msg":10,"message":6,"data":11,"success":54},200,"操作成功",{"id":12,"specialistId":13,"specialistAssistants":14,"profilePhoto":15,"specialistName":16,"hospital":17,"department":18,"postsTitle":19,"materialTotal":20,"videoTotal":21,"isConcern":7,"title":22,"coverVertical":23,"coverAcross":24,"content":25,"description":23,"views":26,"likes":21,"isThumbsUp":7,"isCollection":7,"collections":21,"createTime":27,"seoTitle":28,"seoKeywords":29,"seoDescription":30,"shelvesTime":31,"version":32,"menus":33,"menuId":35,"type":42,"quality":53,"commentCount":21,"isComment":42},65769,867147,[],"https://ystcdn.venuertc.com/medical/ystApp/Kr0RSFx2Uj5YYFrckuGWPvA197lPCliq.png","关园","东辽县人民医院","肿瘤科","主治医师",243,0,"肺癌晚期用药安全实用指南 💊","","https://ystcdn.venuertc.com/venue/AI/16187e80-8a64-42c6-8f01-c94aa401f9af.jpg","\u003Cdiv class=\"jilin-lung-medicine-guide\">\n  \u003Ch1 id=\"material_title\" class=\"jilin-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">肺癌晚期用药安全实用指南 \u003Cspan class=\"jilin-icon\">💊\u003C/span>\u003C/h1>\n  \u003Cdiv class=\"jilin-lead\">\n    说到肺癌晚期的药物治疗，很多吉林市的患者家属关心的不仅是药的种类，还有安全和效果。其实，合理用药是每个人能做到的“主动权”。今天，我们来梳理7个最实用的药品使用细节，包括用法、药物特点、常见副作用等，让用药更放心，也能规避一些使用误区。\n  \u003C/div>\n\n  \u003C!-- 01 服用时间和方法 -->\n  \u003Csection class=\"jilin-section\" style=\"background:linear-gradient(90deg,#e9f6fa 0%, #f9faf9 100%);\">\n    \u003Ch2 class=\"jilin-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">01. 服用时间和方法\u003Cspan class=\"jilin-subicon\">⏰\u003C/span>\u003C/h2>\n    \u003Cdiv class=\"jilin-section-content\">\n      用于肺癌晚期治疗的药物种类较多，像顺铂、培美曲塞、吉非替尼等都需明确服药或输注时间。不同时期的药物，其服用方式也有差异：\n      \u003Cul class=\"jilin-list\">\n        \u003Cli>化疗药（如顺铂、培美曲塞）：通常由专业医师在医院静脉点滴，不适宜自行在家操作。\u003C/li>\n        \u003Cli>口服靶向药（如吉非替尼、厄洛替尼）：每天一次，建议在相同时间服用。有的药要求空腹，有的可以餐后服用，需严格看说明书或遵医嘱。\u003C/li>\n        \u003Cli>免疫药物（如帕博利珠单抗）：多为静脉点滴，一定要定期到指定医院，由专业人员给药。\u003C/li>\n      \u003C/ul>\n      \u003Cspan class=\"jilin-point\">正确做法：\u003C/span>化疗和免疫治疗必须由医护人员操作，口服药则要注意每日同一时间，确保体内药物浓度稳定。不清楚服用细节时，立即咨询医生或药师。\n    \u003C/div>\n  \u003C/section>\n\n  \u003C!-- 02 剂型特点和服用技巧 -->\n  \u003Csection class=\"jilin-section\" style=\"background:linear-gradient(90deg,#f6f4eb 0%, #faf9f9 100%);\">\n    \u003Ch2 class=\"jilin-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">02. 剂型特点和服用技巧\u003Cspan class=\"jilin-subicon\">💡\u003C/span>\u003C/h2>\n    \u003Cdiv class=\"jilin-section-content\">\n      常见的药品剂型有片剂、胶囊、注射液等，不同剂型有不同的正确用药方式：\n      \u003Cul class=\"jilin-list\">\n        \u003Cli>口服片剂/胶囊（如阿法替尼、厄洛替尼）：整片吞服，不要嚼碎，也不建议掰断。用一杯温水送服更利于药物吸收。\u003C/li>\n        \u003Cli>注射剂（如顺铂、帕博利珠单抗）：严禁自行操作，需在医院专科安全使用，避免感染等风险。\u003C/li>\n        \u003Cli>特殊剂型（如缓释片、肠溶片）：不能掰开或嚼碎，否则影响药效或副作用增大。\u003C/li>\n      \u003C/ul>\n      \u003Cspan class=\"jilin-dot\">特别提醒：\u003C/span>药品包装有明确标识时，请按照说明操作。服药过程中如发现胶囊或片剂破损，不要自行服用，应及时换药。\n    \u003C/div>\n  \u003C/section>\n\n  \u003C!-- 03 药物相互作用 -->\n  \u003Csection class=\"jilin-section\" style=\"background:linear-gradient(90deg,#f8f3fa 0%, #fafbf9 100%);\">\n    \u003Ch2 class=\"jilin-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">03. 药物相互作用\u003Cspan class=\"jilin-subicon\">🔗\u003C/span>\u003C/h2>\n    \u003Cdiv class=\"jilin-section-content\">\n      肺癌晚期患者往往需联合用药，药物之间的相互影响必不可少。举几个需要关注的例子：\n      \u003Cul class=\"jilin-list\">\n        \u003Cli>吉非替尼、厄洛替尼等靶向药物与部分抗酸药共用，会减少药效。\u003C/li>\n        \u003Cli>顺铂、培美曲塞可影响肾脏，如果同时服用对肾脏有影响的药（如NSAIDs类止痛药），肾功能风险增加。\u003C/li>\n        \u003Cli>部分抗生素可影响自身代谢药物的酶，导致效果增强或减弱。\u003C/li>\n      \u003C/ul>\n      \u003Cspan class=\"jilin-dot\">正确做法：\u003C/span>如需同时服用多种药物时，请提前标注清单，并将所有用药信息告知医生和药师，以便专业评估可能的药物相互作用，减少不良反应。\n    \u003C/div>\n  \u003C/section>\n\n  \u003C!-- 04 特殊人群用药调整 -->\n  \u003Csection class=\"jilin-section\" style=\"background:linear-gradient(90deg,#f4f8ee 0%, #fafbfa 100%);\">\n    \u003Ch2 class=\"jilin-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">04. 特殊人群用药调整\u003Cspan class=\"jilin-subicon\">👨‍👩‍👧‍👦\u003C/span>\u003C/h2>\n    \u003Cdiv class=\"jilin-section-content\">\n      年龄、肝肾功能、孕产情况都可能影响药品代谢和安全性：\n      \u003Cul class=\"jilin-list\">\n        \u003Cli>65岁以上老年人：个别药品需调整剂量（如部分靶向药，减量以避免副作用）。\u003C/li>\n        \u003Cli>肝肾功能异常者：慎用或禁用某些排泄途径依赖肝肾的药物，如顺铂，严重肾损伤不可用。\u003C/li>\n        \u003Cli>孕妇、哺乳期女性：大多数抗肿瘤药物禁用，建议咨询专科医生，明确用药风险。\u003C/li>\n      \u003C/ul>\n      \u003Cspan class=\"jilin-dot\">特别提醒：\u003C/span>出现肝肾功能异常、体重明显波动时，应主动向医生反馈，由医生调整剂量，不可擅自增减药物用量。\n    \u003C/div>\n  \u003C/section>\n\n  \u003C!-- 05 常见不良反应 -->\n  \u003Csection class=\"jilin-section\" style=\"background:linear-gradient(90deg,#fbeee8 0%, #f8f9f8 100%);\">\n    \u003Ch2 class=\"jilin-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">05. 常见不良反应\u003Cspan class=\"jilin-subicon\">⚠️\u003C/span>\u003C/h2>\n    \u003Cdiv class=\"jilin-section-content\">\n      实际用药过程中，有部分药品的不良反应需要特别关注：\n      \u003Cul class=\"jilin-list\">\n        \u003Cli>吉非替尼：临床研究表明，约40-60%患者出现皮肤干燥和腹泻（Mok et al., NEJM, 2009）。严重时需暂停或调整剂量。\u003C/li>\n        \u003Cli>顺铂：高比例引起恶心、呕吐及肾毒性问题。表现为尿量减少、肢体浮肿时应及时报告。\u003C/li>\n        \u003Cli>培美曲塞：容易造成白细胞减少，增加感染风险。\u003C/li>\n        \u003Cli>免疫类药物：可能出现发热、皮疹或免疫相关反应，极少数会有严重并发症。\u003C/li>\n      \u003C/ul>\n      \u003Cspan class=\"jilin-dot\">正确做法：\u003C/span>一旦出现皮疹、腹泻、发热、异常出血等症状，不要自行停药，应立即联系医生。部分轻微不良反应可短期观察，但持续恶化需及时处理。\n    \u003C/div>\n  \u003C/section>\n\n  \u003C!-- 06 储存条件和有效期 -->\n  \u003Csection class=\"jilin-section\" style=\"background:linear-gradient(90deg,#eff6fa 0%, #f9faf9 100%);\">\n    \u003Ch2 class=\"jilin-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">06. 储存条件和有效期\u003Cspan class=\"jilin-subicon\">📦\u003C/span>\u003C/h2>\n    \u003Cdiv class=\"jilin-section-content\">\n      用药安全不仅要重视服用过程，储存条件同样重要：\n      \u003Cul class=\"jilin-list\">\n        \u003Cli>口服药品：大部分需置于阴凉干燥处，避免潮湿。\u003C/li>\n        \u003Cli>注射剂：多为冷藏（2~8℃），切勿冷冻或高温暴晒，开封后如未用完须立即丢弃。\u003C/li>\n        \u003Cli>外包装原盒保存，避免混乱误用。\u003C/li>\n      \u003C/ul>\n      \u003Cspan class=\"jilin-dot\">正确做法：\u003C/span>定期查看药品有效期，过期药品一律禁止服用。任何颜色、气味变化的药品需要及时更换。\n    \u003C/div>\n  \u003C/section>\n\n  \u003C!-- 07 漏服和过量处理 -->\n  \u003Csection class=\"jilin-section\" style=\"background:linear-gradient(90deg,#f7f3fa 0%, #faf9f9 100%);\">\n    \u003Ch2 class=\"jilin-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">07. 漏服和过量处理\u003Cspan class=\"jilin-subicon\">🔔\u003C/span>\u003C/h2>\n    \u003Cdiv class=\"jilin-section-content\">\n      有时难免出现漏服，关键是如何补救：\n      \u003Cul class=\"jilin-list\">\n        \u003Cli>偶尔漏服：想起后尽快服用；如果接近下次用药时间，不要补服两次，按正常计划继续。\u003C/li>\n        \u003Cli>连续漏服多次或误服过量：务必保留药品包装，尽快咨询医生处理。\u003C/li>\n        \u003Cli>出现不适反应（如呕吐、严重腹泻等）：暂停用药并及时就医。\u003C/li>\n      \u003C/ul>\n      \u003Cspan class=\"jilin-dot\">正确做法：\u003C/span>使用药品记录表，每日打勾降低漏服率。如家庭护理困扰较大，可由家人协助分药管理。\n    \u003C/div>\n  \u003C/section>\n\n  \u003C!--  实际用药案例  -->\n  \u003Csection class=\"jilin-section\" style=\"background:linear-gradient(90deg,#eaf6f6 0%, #fcfafc 100%);\">\n    \u003Ch2 class=\"jilin-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">实际用药案例\u003Cspan class=\"jilin-subicon\">📑\u003C/span>\u003C/h2>\n    \u003Cdiv class=\"jilin-section-content\">\n      \u003Cul class=\"jilin-list\">\n        \u003Cli>有位男性患者在医院按流程使用顺铂和培美曲塞，为防止肾损害，严格控制出入量并监测肾功能。\u003C/li>\n        \u003Cli>临床上发现，部分患者服用吉非替尼后出现皮疹，经及时处理后调整了剂量。\u003C/li>\n        \u003Cli>一位无特殊禁忌的患者，首次使用帕博利珠单抗时，医院专职人员全程观察，未发生明显不良反应。\u003C/li>\n      \u003C/ul>\n      这些用药经历提示：规范操作、密切观察、及时反馈是用药过程中的重要环节。\n    \u003C/div>\n  \u003C/section>\n\n  \u003C!-- 参考文献 -->\n  \u003Csection class=\"jilin-section\" style=\"background:linear-gradient(90deg,#f3f5f6 0%, #f9fafb 100%);\">\n    \u003Ch2 class=\"jilin-subtitle\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">🔎 参考文献（APA格式）\u003C/h2>\n    \u003Cdiv class=\"jilin-section-content jilin-ref\">\n      \u003Cul class=\"jilin-ref-list\">\n        \u003Cli>\n          Mok, T. S., Wu, Y. L., Thongprasert, S., Yang, C. H., Chu, D. T., Saijo, N., ... & Fukuoka, M. (2009). Gefitinib or carboplatin–paclitaxel in pulmonary adenocarcinoma. \u003Cem>New England Journal of Medicine\u003C/em>, 361(10), 947-957.\n        \u003C/li>\n        \u003Cli>\n          National Comprehensive Cancer Network (NCCN). (2023). NCCN Clinical Practice Guidelines in Oncology: Non-Small Cell Lung Cancer. Version 1.2023. \u003Ca href=\"https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1450\" target=\"_blank\">https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1450\u003C/a>\n        \u003C/li>\n        \u003Cli>\n          Herbst, R. S., Morgensztern, D., & Boshoff, C. (2018). The biology and management of non-small cell lung cancer. \u003Cem>Nature\u003C/em>, 553(7689), 446–454.\u003C/li>\u003C/ul>\u003C/div>\u003C/section>\n\u003C/div>\n\u003Cstyle>\n/* 独立样式，命名避免冲突 */\n.jilin-lung-medicine-guide {\n  font-family: \"Segoe UI\", \"Microsoft YaHei\", Arial, sans-serif;\n  max-width: 840px;\n  margin: 24px auto;\n  background: #fff;\n  padding: 32px 28px 34px 28px;\n  border-radius: 24px;\n  box-shadow: 0 4px 24px rgba(84,122,196,0.07);\n  color: #233150;\n  line-height: 1.85;\n}\n.jilin-title {\n  font-size: 2.4em;\n  font-weight: 700;\n  text-align: center;\n  letter-spacing: 0.02em;\n  margin-bottom: 18px;\n  margin-top: 0;\n}\n.jilin-icon {\n  font-size: 1.05em;\n  margin-left: 6px;\n}\n.jilin-lead {\n  font-size: 1.15em;\n  background: #eff8fa;\n  border-left: 8px solid #a3d6ec;\n  padding: 16px 20px 14px 20px;\n  margin-bottom: 28px;\n  color: #326784;\n  border-radius: 9px;\n}\n.jilin-section {\n  margin-bottom: 32px;\n  padding: 28px 22px 18px 22px;\n  border-radius: 17px;\n}\n.jilin-subtitle {\n  font-size: 1.32em;\n  font-weight: 700;\n  display: flex;\n  align-items: center;\n  gap: 0.7em;\n  margin-top: 0;\n  margin-bottom: 16px;\n  letter-spacing: 0.01em;\n  color: #2d5170;\n}\n.jilin-subicon {\n  font-size: 1.16em;\n}\n.jilin-section-content {\n  font-size: 1.04em;\n  padding-left: 3px;\n  padding-bottom: 0;\n}\n.jilin-list {\n  margin-top: 10px;\n  margin-bottom: 12px;\n  padding-left: 22px;\n}\n.jilin-list li {\n  margin-bottom: 5px;\n  list-style: disc outside;\n  padding-left: 2px;\n}\n.jilin-dot, .jilin-point {\n  display: inline-block;\n  font-weight: bold;\n  color: #b0522f;\n  margin-right: 5px;\n}\n.jilin-ref {\n  font-size: 0.97em;\n  color: #5c7080;\n}\n.jilin-ref-list {\n  padding-left: 18px;\n}\n.jilin-ref-list li {\n  margin-bottom: 7px;\n  line-height: 1.6em;\n  word-break: break-all;\n}\n@media (max-width: 600px) {\n  .jilin-lung-medicine-guide {\n    padding: 14px 5px 18px 7px;\n    border-radius: 9px;\n  }\n  .jilin-title {\n    font-size: 1.2em;\n  }\n  .jilin-section {\n    padding: 12px 5px 10px 10px;\n    border-radius: 7px;\n  }\n  .jilin-subtitle {\n    font-size: 1em;\n    gap: 0.25em;\n    margin-bottom: 6px;\n  }\n  .jilin-section-content {\n    font-size: 0.97em;\n  }\n}\n\u003C/style>\n\n",506,"2025-09-05 14:05:50"," 肺癌晚期用药安全实用指南 - 专家建议与安全用药贴士 💊  \n"," 肺癌晚期用药, 安全用药指南, 肺癌治疗药物, 晚期肺癌护理, 抗癌药物安全, 化疗注意事项, 靶向治疗副作用  \n"," 本指南提供肺癌晚期患者安全用药的实用建议，涵盖化疗、靶向治疗等药物的正确使用方法、常见副作用管理及用药禁忌，帮助患者和家属科学应对治疗挑战。💊","2025-09-09 09:41:58",2,[34],{"menuId":35,"menuName":36,"parentId":21,"orderNum":32,"path":37,"component":38,"isFrame":39,"isCache":40,"menuType":41,"visible":42,"status":21,"createDept":6,"remark":23,"createTime":43,"children":44,"columnImage":45,"columnLogo":46,"uncheckedLogo":6,"checkedLogo":6,"isHot":42,"isHome":21,"forceLogin":21,"color":47,"seoTitle":48,"seoKeywords":49,"seoDescription":50,"contentNum":6,"promotionalPoster":51,"menuFrame":7,"innerLink":7,"parentView":7,"routeName":52,"routerPath":37,"componentInfo":38},"1986713082609147906","健康科普","article","/article.html","1","0","T",1,"2025-11-07 16:31:25",[],"https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:49/d4291d16-ed1c-48dd-84c8-ec1f85980b75.png","https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:52/6fe64094-9416-442c-a66d-032fb292666a.png","#c8e6ca","健康科普助力健康中国2030:共享健康知识新理念","健康科普, 健康中国, 科普知识, 健康家庭, 性健康, 营养健康, 运动健康, 科普宣传","探索健康科普在健康中国行动中的重要角色,了解最新的健康科普创新大赛、动漫及短视频,传播健康知识,助力全民健康。","https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:56/bd33f471-6c54-4d1b-a364-b06973dbc144.png","Article","癌症肿瘤,重大疾病",true,{"code":9,"msg":10,"message":6,"data":56,"success":54},{"pageNo":42,"pageSize":57,"result":58,"totalSize":21},10,[],{"code":9,"msg":10,"message":6,"data":60,"success":54},{"authors":61,"appraiseDimensionScoresVos":62},[],[]]