[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$f65-g5LTUgHIk8dGZIHhGe2pKpxnfW0g-O4HGxk3yxcs":3,"$fkw-UaPIQdFgvbu30s9nie1SrLv8LrXaUWvQMM-zeKLw":8,"$f_BR3B8lXEPG7IcysUQYL2W4-SoL_4qsCu2KBaMwTZj0":55,"$frw7k10kTHjaZiJdpsHMT20YeTGeqwqZRKy-mS8MM21E":59},{"code":4,"msg":5,"message":6,"data":6,"success":7},401,"认证失败，无法访问系统资源",null,false,{"code":9,"msg":10,"message":6,"data":11,"success":54},200,"操作成功",{"id":12,"specialistId":13,"specialistAssistants":14,"profilePhoto":15,"specialistName":16,"hospital":17,"department":18,"postsTitle":19,"materialTotal":20,"videoTotal":21,"isConcern":7,"title":22,"coverVertical":23,"coverAcross":24,"content":25,"description":26,"views":27,"likes":21,"isThumbsUp":7,"isCollection":7,"collections":21,"createTime":28,"seoTitle":22,"seoKeywords":29,"seoDescription":30,"shelvesTime":31,"version":32,"menus":33,"menuId":35,"type":42,"quality":53,"commentCount":21,"isComment":42},53815,868612,[],"https://cdn.haohuanjiao.com/learnMaterial/ystApp//aEjvqWJyaGzRDDYxpbM3JGk58uOu7fQX.png","李俊杰","桓台县人民医院","血管外科","主治医师",16,0,"前列腺癌IV期最新用药指南：多西他赛、戈舍瑞林等关键安全细节","","https://ystcdn.venuertc.com/venue/AI/3c4e84af-9efa-4909-b6ce-6351304d6ca9.jpg","\u003Cdiv class=\"prostate-meds-material\">\n\n  \u003Ch2 class=\"prostate-meds-title\" id=\"material_title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">前列腺癌IV期最新用药指南：多西他赛、戈舍瑞林等关键安全细节\u003C/h2>\n  \n  \u003Cdiv class=\"material-intro prostate-meds-bg-soft\">\n    \u003Cp>\n      说起多西他赛和戈舍瑞林，这两种药物在肿瘤专科用药中不算陌生，尤其是在高级阶段的药物选择里。作为化疗和内分泌常规方案的重要成员，它们各自有着复杂的用药要求。想用好、用安全，很大程度上取决于对关键用药细节的把控。今天，咱们就来拆解多西他赛、戈舍瑞林和相关药物使用时最值得关注的7件事，为安全用药多加一层保障。\n    \u003C/p>\n  \u003C/div>\n\n  \u003Csection class=\"prostate-meds-section\">\n    \u003Ch2 class=\"prostate-meds-subtitle prostate-meds-bg-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">01. 主要药物成分及剂型特点 🔎\u003C/h2>\n    \u003Cdiv class=\"prostate-meds-bg-block\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>多西他赛 (Docetaxel)：\u003C/strong> 一种紫杉烷类的化疗药物。常见规格为20 mg/0.5 ml和80 mg/2 ml注射液，仅供静脉滴注使用，不可用于口服。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>戈舍瑞林 (Goserelin)：\u003C/strong> 一种促黄体生成素释放激素（LHRH）类似物，市面上多以3.6 mg或10.8 mg的皮下植入剂为主，常通过腹部皮下注射植入，维持长效药效。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>醋酸亮丙瑞林（Leuprorelin acetate）：\u003C/strong>  同为激素类，常见3.75 mg、7.5 mg、11.25 mg等缓释植入剂，给药方式和戈舍瑞林相似。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>多西他赛配用液：\u003C/strong> 通常附带配套溶剂，使用时需稀释，不建议直接操作原液。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        正确做法：务必核查剂型和规格，药品应由专业人员按说明书正规配置和操作，避免误用剂型导致用药失败或风险升高。\n      \u003C/p>\n    \u003C/div>\n  \u003C/section>\n\n  \u003Csection class=\"prostate-meds-section\">\n    \u003Ch2 class=\"prostate-meds-subtitle prostate-meds-bg-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">02. 作用机制简析🌱\u003C/h2>\n    \u003Cdiv class=\"prostate-meds-bg-block\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>多西他赛：\u003C/strong> 通过稳定微管结构，抑制癌细胞分裂，使细胞周期停滞，从而阻断细胞增殖（参考: \u003Cspan class=\"prostate-meds-ref\">Ringel & Horwitz, 1991, Journal of the National Cancer Institute\u003C/span>）。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>戈舍瑞林：\u003C/strong> 模拟体内促性腺激素释放激素，长期作用下可使性激素水平明显下降，实现“化学去势”效果（参考: \u003Cspan class=\"prostate-meds-ref\">Stein et al., 2000, British Journal of Cancer\u003C/span>）。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>醋酸亮丙瑞林：\u003C/strong> 类似于戈舍瑞林，作用机制为持续性降调节垂体促性腺激素释放，抑制下游性激素产生。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        指南建议：针对转移性及激素敏感型阶段，化疗与内分泌有不同机制，实际应用需个体化权衡。\n      \u003C/p>\n    \u003C/div>\n  \u003C/section>\n\n  \u003Csection class=\"prostate-meds-section\">\n    \u003Ch2 class=\"prostate-meds-subtitle prostate-meds-bg-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">03. 推荐用法用量与操作流程📅\u003C/h2>\n    \u003Cdiv class=\"prostate-meds-bg-block\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>多西他赛：\u003C/strong>\n          \u003Cul>\n            \u003Cli>\n              标准剂量多为每次75 mg/m\u003Csup>2\u003C/sup>，每三周静脉滴注一次（可根据患者体表面积调整），滴注时间常为1小时左右。\n            \u003C/li>\n            \u003Cli>\n              \u003Cspan style=\"color:#b87c29;\">不可口服，不能肌肉注射，也不能自行加快滴速。\u003C/span>\n            \u003C/li>\n            \u003Cli>\n              建议全程由肿瘤专科护理操作，严格执行无菌、滴速和输注顺序，配药时须带齐保护（因多西他赛为黏膜毒性高的药）。\n            \u003C/li>\n          \u003C/ul>\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>戈舍瑞林：\u003C/strong>\n          \u003Cul>\n            \u003Cli>\n              常规剂量3.6 mg皮下植入，每28天一次；10.8 mg规格可3个月一次。\n            \u003C/li>\n            \u003Cli>\n              药物为缓释型植入体，不能裁剪，勿自行更换部位，每次选新注射点。\n            \u003C/li>\n            \u003Cli>\n              特别提醒：需要用专用注射器，宜由护理专业人员实施。\n            \u003C/li>\n          \u003C/ul>\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>醋酸亮丙瑞林：\u003C/strong>  与戈舍瑞林操作相似，具体剂量依医嘱调整。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        正确做法：每次治疗务必确认药品名称、剂量和有效期，避免混淆药物或错误给药时间。\n      \u003C/p>\n      \u003Cp>\n        \u003Cem class=\"prostate-meds-emoji\">💡\u003C/em>临床案例：有位患者在多西他赛化疗周期前未按要求检查血象，导致严重骨髓抑制。因此，开始新一轮化疗前，检查血常规至关重要。\n      \u003C/p>\n    \u003C/div>\n  \u003C/section>\n\n  \u003Csection class=\"prostate-meds-section\">\n    \u003Ch2 class=\"prostate-meds-subtitle prostate-meds-bg-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">04. 特殊人群用药调整与注意⚖️\u003C/h2>\n    \u003Cdiv class=\"prostate-meds-bg-block\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>老年患者：\u003C/strong> 多西他赛和内分泌药物均需评估肝肾功能。若肝功能不佳，剂量通常需下调，个别肝衰竭者严禁使用多西他赛。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>肾功能减退者：\u003C/strong> 内分泌药物对肾损影响小，多西他赛须谨慎，必要时延长给药间隔或调整剂量。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>孕妇/哺乳期：\u003C/strong> 所有上述药物均禁止在孕期及哺乳期使用。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>儿童和未成年人：\u003C/strong> 目前不建议用于未成年人。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        正确做法：如有高龄、肝肾异常或孕产史，提前告知医生，由专业团队评估后再决定用药方式。\n      \u003C/p>\n      \u003Cp>\n        \u003Cem class=\"prostate-meds-emoji\">🔔\u003C/em> 实际使用中，临床注意到高龄患者化疗副作用明显增加，因此剂量需更加个体化。\n      \u003C/p>\n    \u003C/div>\n  \u003C/section>\n\n  \u003Csection class=\"prostate-meds-section\">\n    \u003Ch2 class=\"prostate-meds-subtitle prostate-meds-bg-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">05. 常见不良反应与处理建议🩺\u003C/h2>\n    \u003Cdiv class=\"prostate-meds-bg-block\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>多西他赛：\u003C/strong>\n          \u003Cul>\n            \u003Cli>最常见为骨髓抑制：表现为白细胞、血小板降低，定期血常规监测。\u003C/li>\n            \u003Cli>其他有脱发、口腔炎、指甲改变，偶见过敏反应。\u003C/li>\n            \u003Cli>重度副作用（如急性过敏反应、持续发热）应立即就医。\u003C/li>\n          \u003C/ul>\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>戈舍瑞林及同类内分泌药：\u003C/strong>\n          \u003Cul>\n            \u003Cli>前期可能有一过性激素升高相关反应。\u003C/li>\n            \u003Cli>常见副作用有潮热、盗汗、性欲减退、骨密度下降等。\u003C/li>\n            \u003Cli>部分患者出现注射部位红肿、硬结。\u003C/li>\n            \u003Cli>发生严重全身反应（如过敏性休克）时，需紧急送医。\u003C/li>\n          \u003C/ul>\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        处理方法：连续出现不适症状可先向医生咨询，严重情况勿自行停药，应第一时间求助医疗人员。\u003Cbr>\n        \u003Cem class=\"prostate-meds-emoji\">📝\u003C/em> 案例提示：有患者在多西他赛3个疗程后出现IV度骨髓抑制，后续延缓一次化疗，最终血象恢复方可继续用药（仅供药品经验参考）。\n      \u003C/p>\n    \u003C/div>\n  \u003C/section>\n\n  \u003Csection class=\"prostate-meds-section\">\n    \u003Ch2 class=\"prostate-meds-subtitle prostate-meds-bg-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">06. 药物相互作用与配伍原则⚗️\u003C/h2>\n    \u003Cdiv class=\"prostate-meds-bg-block\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>多西他赛：\u003C/strong>\n          \u003Cul>\n            \u003Cli>严格避免与强抑制或诱导肝酶的药物（如酮康唑、伊曲康唑等真菌药）同时使用，否则血药浓度受影响。\u003C/li>\n            \u003Cli>应与钙通道阻断剂、某些抗癫痫药等药物分开用药，部分可延长多西他赛排泄。\u003C/li>\n          \u003C/ul>\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>戈舍瑞林：\u003C/strong>\n          \u003Cul>\n            \u003Cli>与抗凝药如华法林共同用药，可能增加出血风险。\u003C/li>\n            \u003Cli>长期应用内分泌药物时如需配合降压、降糖等药物，务必先询问药师。\u003C/li>\n          \u003C/ul>\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        正确做法：用药期间如需增加新药，提前核查相互作用清单，有疑问时由药师评估是否存在安全风险。\u003Cbr>\n        日常配合营养保健品同样可能影响血药水平，配合维生素、矿物质补充剂等需注意与主药的间隔时间。\n      \u003C/p>\n      \u003Cp>\n        \u003Cspan class=\"prostate-meds-emoji\">🛑\u003C/span>\n        临床提醒：一位老年患者多西他赛治疗期合并服用酮康唑，导致多西他赛血药浓度升高出现不良反应，停用酮康唑后症状缓解。必须关注药物配伍。\n      \u003C/p> \n    \u003C/div>\n  \u003C/section>\n\n  \u003Csection class=\"prostate-meds-section\">\n    \u003Ch2 class=\"prostate-meds-subtitle prostate-meds-bg-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">07. 药品储存与使用有效期📦\u003C/h2>\n    \u003Cdiv class=\"prostate-meds-bg-block\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>多西他赛：\u003C/strong> 建议密封避光、置于15-25℃干燥环境。已配制好的溶液需4小时内用完，不可冷冻。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>戈舍瑞林、亮丙瑞林：\u003C/strong> 应冷藏（2-8℃）或按药品标签保存，避免反复升温降温。一次使用未尽药品禁止下次再用，剩余药体需安全弃置。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        过期、变质或受污染药品严禁使用。配药人员每次均应核查药品包装、有效期与批号。\n      \u003C/p>\n    \u003C/div>\n  \u003C/section>\n\n  \u003Csection class=\"prostate-meds-section\">\n    \u003Ch2 class=\"prostate-meds-subtitle prostate-meds-bg-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">08. 漏服、补药及过量处理⏲️\u003C/h2>\n    \u003Cdiv class=\"prostate-meds-bg-block\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>多西他赛：\u003C/strong> 如漏服无需自行补药，下个化疗周期根据医嘱重新调整。\u003Cspan style=\"color:#802020\">过量服用可致重度抑制和脏器损伤\u003C/span>，一旦怀疑过量应立刻就医。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>戈舍瑞林：\u003C/strong> 漏用应尽快补打，新一次注射时间以医生安排为准。严禁私自改变注射频率。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        出现恶心、发热、精神状态异常等不适，及时联系医疗团队。\n      \u003C/p>\n    \u003C/div>\n  \u003C/section>\n\n  \u003Csection class=\"prostate-meds-section\">\n    \u003Ch2 class=\"prostate-meds-subtitle prostate-meds-bg-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">09. 补充前沿——耐药机制与新靶点简析🧬\u003C/h2>\n    \u003Cdiv class=\"prostate-meds-bg-block\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cspan style=\"color:#105680;\">最新研究显示：\u003C/span> 癌症干细胞相关通路活跃时，多西他赛化疗易出现耐药。特定基因（AGD1/MPLL13通路等）影响前列腺癌细胞对多西他赛的化疗敏感性。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>科学前沿：\u003C/strong> 通过靶向前述新基因，可增强多西他赛疗效，降低耐药风险，但有关新药尚在临床前阶段，实际临床用药依然以常规指南为主。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        \u003Cspan class=\"prostate-meds-emoji\">🔬\u003C/span>\n        研究参考：Shen et al., \"AGD1/USP10/METTL13 complexes enhance cancer stem cells proliferation and diminish the therapeutic effect of docetaxel\", \u003Cem>J Exp Clin Cancer Res\u003C/em>, 2025.\n      \u003C/p>\n    \u003C/div>\n  \u003C/section>\n\n  \u003Csection class=\"prostate-meds-section\">\n    \u003Ch2 class=\"prostate-meds-subtitle prostate-meds-bg-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">10. 最重要的安全提示与总结\u003C/h2>\n    \u003Cdiv class=\"prostate-meds-bg-block prostate-meds-bg-highlight\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>必须专业操作，严禁自行用药或擅自调整剂量。\u003C/strong>\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>用药期间需定期监测血常规、肝肾功能，如有不适及时就医，绝不能自行停药。\u003C/strong>\n        \u003C/li>\n        \u003Cli>\n          每次用药前确认药品、剂型、有效期，严格遵医嘱给药。\n        \u003C/li>\n        \u003Cli>\n          若需合用其他药物、保健品、或有特殊情况（如老年、功能异常），务必主动告知医疗人员。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        \u003Cspan class=\"prostate-meds-emoji\">✅\u003C/span> 只要把好这些关键细节的“门”，多西他赛、戈舍瑞林等药物就在患者健康路上发挥最大作用。用药安全大于一切，有疑问请随时专业咨询。\n      \u003C/p>\n    \u003C/div>\n  \u003C/section>\n\n  \u003Csection class=\"prostate-meds-section\">\n    \u003Ch2 class=\"prostate-meds-subtitle prostate-meds-bg-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">主要英文文献引用（APA格式）\u003C/h2>\n    \u003Cdiv class=\"prostate-meds-bg-block prostate-meds-bg-refblock\">\n      \u003Col class=\"prostate-meds-ref-list\">\n        \u003Cli>\n          Ringel, I., & Horwitz, S. B. (1991). Taxol and taxotere: Similarities and differences. \u003Cem>Journal of the National Cancer Institute\u003C/em>, 83(5), 288–291. https://doi.org/10.1093/jnci/83.5.288\n        \u003C/li>\n        \u003Cli>\n          Stein, R. C., et al. (2000). Endocrine therapy for prostate cancer. \u003Cem>British Journal of Cancer\u003C/em>, 82(7), 1233–1242. https://doi.org/10.1054/bjoc.2000.1066\n        \u003C/li>\n        \u003Cli>\n          Shen, S., et al. (2025). AGD1/USP10/METTL13 complexes enhance cancer stem cells proliferation and diminish the therapeutic effect of docetaxel via CD44 m6A modification in castration resistant prostate cancer. \u003Cem>Journal of Experimental & Clinical Cancer Research\u003C/em>, 44, Article 272. https://jeccr.biomedcentral.com/articles/10.1186/s13046-025-03272-3\n        \u003C/li>\n      \u003C/ol>\n    \u003C/div>\n  \u003C/section>\n\n\u003C/div>\n\u003Cstyle>\n.prostate-meds-material { \n  font-family: \"Segoe UI\", Arial, sans-serif; \n  background: #fcfcfc; \n  color: #183042; \n  line-height: 2;\n  max-width: 820px;\n  margin: 32px auto;\n  padding: 36px;\n  border-radius: 20px;\n  box-shadow: 0 2px 36px 0 rgba(35,77,95,0.09);\n  border: 1px solid #eef2f4;\n}\n.prostate-meds-title {\n  font-size: 2.3em; \n  font-weight: bold; \n  margin-bottom: 24px;\n  color: #2347af;\n  letter-spacing: 1.5px;\n  text-shadow: 0 2px 8px #f0f2fa;\n}\n.material-intro {\n  margin-bottom: 30px;\n  border-radius: 16px;\n  padding: 28px 28px;\n  background: linear-gradient(90deg, #fafbfc 70%, #e1edfa 95%);\n  font-size: 1.16em;\n}\n.prostate-meds-bg-soft {\n  background: #f5fafe;\n}\n.prostate-meds-section { \n  margin-bottom: 38px; \n}\n.prostate-meds-subtitle {\n  font-size: 1.4em;\n  font-weight: 600;\n  margin-bottom: 10px;\n  margin-top: 0;\n  padding: 12px 24px;\n  color: #2567a7;\n  border-left: 8px solid #67afe1;\n  border-radius: 15px 0 16px 0;\n  box-shadow: 0 2px 12px rgba(190,222,251,0.11);\n  background: linear-gradient(to right,#e1f2fd 80%,#f5fafe 100%);\n  letter-spacing: 1.1px;\n  display: flex;\n  align-items: center;\n}\n.prostate-meds-bg-title {\n  background: linear-gradient(90deg, #e8f3fa 65%, #f7fafd 100%);\n}\n.prostate-meds-bg-block {\n  border-radius: 15px;\n  background: linear-gradient(108deg, #f6fafd 60%, #f3f6fd 100%);\n  padding: 25px 19px 22px 28px;\n  margin-top: 12px;\n  margin-bottom: 8px;\n  font-size: 1.05em;\n  box-shadow: 0 0 0 1px #e3eaf2;\n}\n.prostate-meds-emoji {\n  font-size: 1.16em;\n  vertical-align: middle;\n  margin-right: 5px;\n}\n.prostate-meds-bg-highlight {\n  background: linear-gradient(91deg, #e3f1e6 10%, #fcfff9 100%);\n  box-shadow: 0 2px 16px rgba(126,179,160,0.12);\n  border-left: 8px solid #48ad88;\n}\n.prostate-meds-ref {\n  color: #388dde;\n  font-style: italic;\n  font-size: 1em;\n}\n.prostate-meds-ref-list li {\n  margin-bottom: 12px;\n  font-size: 1.028em;\n}\n.prostate-meds-bg-refblock {\n  background: #fcfdfc;\n  border: 1px dashed #88aad3;\n  border-radius: 14px;\n  padding: 22px 25px;\n  margin-top: 14px;\n}\n.prostate-meds-bg-block ul, .prostate-meds-bg-refblock ol {\n  margin: 0 0 0 16px;\n  padding: 0 0 0 16px;\n}\n.prostate-meds-bg-block li, .prostate-meds-bg-refblock li {\n  margin-bottom: 10px;\n}\n@media (max-width:680px) {\n  .prostate-meds-material {max-width:97%;padding: 12px 2%;}\n  .prostate-meds-title {font-size: 1.5em;}\n  .material-intro, .prostate-meds-bg-block, .prostate-meds-bg-refblock {padding: 15px 6px;}\n}\n\u003C/style>\n","\u003Cdiv class=\"prostate-meds-material\">\n\n  \u003Ch2 class=\"prostate-meds-title\" id=\"material_title\" style=\"c",534,"2025-07-29 13:50:43","前列腺癌, 多西他赛, 戈舍瑞林, 用药指南, 不良反应, 安全用药, 药物相互作用, 化疗","深入解读前列腺癌IV期用药的关键细节，掌握多西他赛和戈舍瑞林的使用要求，确保安全与有效。了解用药的风险、作用机制与建议操作流程，助力患者和护理人员应对复杂病情。","2025-07-30 13:56:00",2,[34],{"menuId":35,"menuName":36,"parentId":21,"orderNum":32,"path":37,"component":38,"isFrame":39,"isCache":40,"menuType":41,"visible":42,"status":21,"createDept":6,"remark":23,"createTime":43,"children":44,"columnImage":45,"columnLogo":46,"uncheckedLogo":6,"checkedLogo":6,"isHot":42,"isHome":21,"forceLogin":21,"color":47,"seoTitle":48,"seoKeywords":49,"seoDescription":50,"contentNum":6,"promotionalPoster":51,"menuFrame":7,"innerLink":7,"parentView":7,"routeName":52,"routerPath":37,"componentInfo":38},"1986713082609147906","健康科普","article","/article.html","1","0","T",1,"2025-11-07 16:31:25",[],"https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:49/d4291d16-ed1c-48dd-84c8-ec1f85980b75.png","https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:52/6fe64094-9416-442c-a66d-032fb292666a.png","#c8e6ca","健康科普助力健康中国2030:共享健康知识新理念","健康科普, 健康中国, 科普知识, 健康家庭, 性健康, 营养健康, 运动健康, 科普宣传","探索健康科普在健康中国行动中的重要角色,了解最新的健康科普创新大赛、动漫及短视频,传播健康知识,助力全民健康。","https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:56/bd33f471-6c54-4d1b-a364-b06973dbc144.png","Article","癌症肿瘤,重大疾病",true,{"code":9,"msg":10,"message":6,"data":56,"success":54},{"pageNo":42,"pageSize":57,"result":58,"totalSize":21},10,[],{"code":9,"msg":10,"message":6,"data":60,"success":54},{"authors":61,"appraiseDimensionScoresVos":62},[],[]]