[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$f65-g5LTUgHIk8dGZIHhGe2pKpxnfW0g-O4HGxk3yxcs":3,"$fYuF39ES0dDo6EiHDFRJXQxW2jFKNidbl2LU8Xff8ujk":8,"$fl_Fid6XzffCYBhOtNH2lKIHGs7jbZwosv-M2JVRsf04":55,"$fNR6MVyQoYP1wBJqLh6oWqPIYLSQoswK6LREvywwV290":59},{"code":4,"msg":5,"message":6,"data":6,"success":7},401,"认证失败，无法访问系统资源",null,false,{"code":9,"msg":10,"message":6,"data":11,"success":54},200,"操作成功",{"id":12,"specialistId":13,"specialistAssistants":14,"profilePhoto":15,"specialistName":16,"hospital":17,"department":18,"postsTitle":19,"materialTotal":20,"videoTotal":21,"isConcern":7,"title":22,"coverVertical":23,"coverAcross":24,"content":25,"description":26,"views":27,"likes":21,"isThumbsUp":7,"isCollection":7,"collections":21,"createTime":28,"seoTitle":22,"seoKeywords":29,"seoDescription":30,"shelvesTime":31,"version":32,"menus":33,"menuId":35,"type":42,"quality":53,"commentCount":21,"isComment":42},53428,867218,[],"https://ystcdn.venuertc.com/medical/ystApp/PNv1JgZKMO3NbzWop7HvWPziztZOf4zJ.png","吕昭宝","聊城市第二人民医院","甲状腺乳腺外科","主治医师",183,0,"肺癌一阶段：治疗选择与药品安全用药指南","","https://ystcdn.venuertc.com/venue/AI/d4a1bb2f-a4e5-4843-b9fa-72f56772aa55.jpg","\u003Cdiv class=\"lung-drug-guide-container\">\n  \u003Cdiv class=\"lung-drug-guide-header\" id=\"material_title\">\n    \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">肺癌一阶段：治疗选择与药品安全用药指南\u003C/h2>\n    \u003Cp class=\"lung-drug-guide-subtitle\">\n      靶向治疗、免疫抑制、化疗与骨保护——用药关键细节全梳理\n    \u003C/p>\n  \u003C/div>\n\n  \u003Cdiv class=\"lung-drug-guide-section\">\n    \u003Cdiv class=\"lung-drug-guide-title\" style=\"background:linear-gradient(90deg,#eaf6ff 60%,#f2f2f2 100%)\">\n      \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">01 ▶ 药品分类与作用机制简介\u003C/h2>\n    \u003C/div>\n    \u003Cdiv class=\"lung-drug-guide-content\">\n      \u003Cp>\n        说起来，临床用于治疗肺部肿瘤的药品门类不少。当前常用的包括靶向治疗药（如BRAF抑制剂、MEK抑制剂）、免疫抑制剂（如PD-1通路抑制剂）、经典化疗药（像培美曲塞、卡铂）以及骨保护剂（如双膦酸盐）。每种药物背后的原理不一样——\n      \u003C/p>\n      \u003Cul>\n        \u003Cli>\u003Cspan class=\"emoji\">🎯\u003C/span> \u003Cb>靶向治疗药\u003C/b>：直接针对肿瘤生长相关的特定基因或蛋白，阻断其功能。\u003C/li>\n        \u003Cli>\u003Cspan class=\"emoji\">🛡️\u003C/span> \u003Cb>免疫抑制剂\u003C/b>：解除肿瘤对免疫系统的“伪装”，激活免疫细胞杀伤异常细胞。\u003C/li>\n        \u003Cli>\u003Cspan class=\"emoji\">💊\u003C/span> \u003Cb>化疗药物\u003C/b>：阻止细胞分裂，对生长迅速细胞（包括异常细胞）有较强抑制。\u003C/li>\n        \u003Cli>\u003Cspan class=\"emoji\">🦴\u003C/span> \u003Cb>骨保护剂\u003C/b>：防止骨量快速流失，降低骨相关事件风险。\u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        不同药品联用时，往往需根据病情和耐受性综合选择。下面就分门别类，细讲各自的安全用药细节。\n      \u003C/p>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"lung-drug-guide-section\">\n      \u003Cdiv class=\"lung-drug-guide-title\" style=\"background:linear-gradient(90deg,#f9f9eb 50%,#e6e9f0 100%)\">\n        \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">02 ▶ 靶向药物（BRAF抑制剂、MEK抑制剂）用药要点\u003C/h2>\n      \u003C/div>\n      \u003Cdiv class=\"lung-drug-guide-content\">\n        \u003Cp>\n          \u003Cb>BRAF抑制剂\u003C/b>（如达拉非尼 Dabrafenib）和\u003Cb>MEK抑制剂\u003C/b>（如曲美替尼 Trametinib）常联合用药，抑制异常信号通路。用于体内braf基因突变患者。\n        \u003C/p>\n        \u003Cul>\n          \u003Cli>\u003Cb>服用方式\u003C/b>：多为口服胶囊或片剂，需按说明整粒吞服。BRAF抑制剂通常空腹服用，MEK抑制剂多建议餐前1小时或餐后2小时。\u003C/li>\n          \u003Cli>\u003Cb>剂量规范\u003C/b>：严格按医生处方剂量服药。自行增减都会影响疗效。\u003C/li>\n          \u003Cli>\u003Cb>漏服处理\u003C/b>：若忘记服药，距离下次服用超过6小时，可补服一次。否则直接跳过，不可双倍剂量。\u003C/li>\n        \u003C/ul>\n        \u003Ch4>特殊人群用药注意 \u003Cspan class=\"emoji\">👴🏻\u003C/span>\u003C/h4>\n        \u003Cul>\n          \u003Cli>肝肾功能减退者需调整剂量，并密切监测。\u003C/li>\n          \u003Cli>老年人应减量起始，逐步调整。\u003C/li>\n          \u003Cli>孕妇及哺乳期妇女禁用，如确有必要应严格避孕。\u003C/li>\n        \u003C/ul>\n        \u003Ch4>常见不良反应与应对 \u003Cspan class=\"emoji\">⚠️\u003C/span>\u003C/h4>\n        \u003Cul>\n          \u003Cli>发热、皮疹、关节疼痛较常见，出现高热时需及时就医。\u003C/li>\n          \u003Cli>皮肤病变（包括光敏反应），用药期间应避免强光暴晒并使用防晒措施。\u003C/li>\n          \u003Cli>肝功能异常：需定期进行肝功能检查。\u003C/li>\n        \u003C/ul>\n        \u003Ch4>储存与有效期\u003C/h4>\n        \u003Cul>\n          \u003Cli>建议保持阴凉干燥，常温（15-30℃）保存。\u003C/li>\n          \u003Cli>避免潮湿和高温，过期药品应妥善丢弃。\u003C/li>\n        \u003C/ul>\n        \u003Ch4>药物相互作用\u003C/h4>\n        \u003Cul>\n          \u003Cli>避免联用强CYP3A4诱导剂或抑制剂（如利福平、酮康唑等），会影响药效。\u003C/li>\n          \u003Cli>BRAF抑制剂可影响某些降糖药、心脏药物血浓度，联用时须咨询医生。\u003C/li>\n        \u003C/ul>\n        \u003Cdiv class=\"lung-drug-guide-case\">\n          \u003Cp>\n            \u003Cspan class=\"emoji\">📝\u003C/span> 有位老年患者使用BRAF和MEK抑制剂联合治疗期间，严格按时服药，未出现严重副作用，常规体检有助于预防问题。\n          \u003C/p>\n        \u003C/div>\n        \u003Cp class=\"lung-drug-guide-ref\">\n          参考文献：Long, G.V. et al., \"Dabrafenib and Trametinib Combination Therapy for Patients with BRAF-mutant Metastatic Melanoma: Long-term Survival in Phase II/III trials,\" Annals of Oncology, 2017.\n        \u003C/p>\n      \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"lung-drug-guide-section\">\n      \u003Cdiv class=\"lung-drug-guide-title\" style=\"background:linear-gradient(90deg,#e8f6e9 60%,#f2eaf2 100%)\">\n        \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">03 ▶ 免疫治疗用药细节（PD-1抑制剂）\u003C/h2>\n      \u003C/div>\n      \u003Cdiv class=\"lung-drug-guide-content\">\n        \u003Cp>\n          \u003Cb>PD-1抑制剂\u003C/b>（如帕博利珠单抗 Pembrolizumab、纳武利尤单抗 Nivolumab）为注射用药，通过阻断免疫系统“刹车”，让异常细胞无处遁形。\n        \u003C/p>\n        \u003Cul>\n          \u003Cli>\u003Cb>给药方式\u003C/b>：大多为静脉输注，根据体表面积或体重调整。间隔2-3周给药一次较常见。\u003C/li>\n          \u003Cli>\u003Cb>用药周期\u003C/b>：一个疗程通常为2-4周期，每周期疗效和不良反应需密切随访。\u003C/li>\n        \u003C/ul>\n        \u003Ch4>联合用药注意 \u003Cspan class=\"emoji\">➕\u003C/span>\u003C/h4>\n        \u003Cul>\n          \u003Cli>可和靶向药或化疗药联用，但组合方案需要严格监控副作用。\u003C/li>\n        \u003C/ul>\n        \u003Ch4>常见副作用 \u003Cspan class=\"emoji\">⚠️\u003C/span>\u003C/h4>\n        \u003Cul>\n          \u003Cli>皮肤反应如皮疹、瘙痒。\u003C/li>\n          \u003Cli>疲劳、发热、食欲减退。\u003C/li>\n          \u003Cli>免疫相关性肝炎、甲状腺功能紊乱（需定期监测血常规与肝肾功能）。\u003C/li>\n        \u003C/ul>\n        \u003Ch4>用药禁忌\u003C/h4>\n        \u003Cul>\n          \u003Cli>曾经发生过严重免疫相关不良反应者禁用。\u003C/li>\n          \u003Cli>自身免疫性疾病患者、器官移植患者慎用。\u003C/li>\n        \u003C/ul>\n        \u003Ch4>特殊人群\u003C/h4>\n        \u003Cul>\n          \u003Cli>孕妇或哺乳者应避免使用。\u003C/li>\n          \u003Cli>年龄大于70岁的患者，建议治疗前全身评估功能状态。\u003C/li>\n        \u003C/ul>\n        \u003Ch4>储存说明\u003C/h4>\n        \u003Cul>\n          \u003Cli>需于2-8°C冷藏，切忌冷冻或受热。\u003C/li>\n          \u003Cli>启用后应尽快输注，剩余药品丢弃。\u003C/li>\n        \u003C/ul>\n        \u003Cdiv class=\"lung-drug-guide-case\">\n          \u003Cp>\n            \u003Cspan class=\"emoji\">🔬\u003C/span> 一名患者PD-1抑制剂与化疗联合治疗，过程中仅出现轻微疲劳，未发生严重副作用，显示用药安全可控。\n          \u003C/p>\n        \u003C/div>\n        \u003Cp class=\"lung-drug-guide-ref\">\n          参考文献：Reck, M. et al., \"Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer,\" New England Journal of Medicine, 2016.\n        \u003C/p>\n      \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"lung-drug-guide-section\">\n      \u003Cdiv class=\"lung-drug-guide-title\" style=\"background:linear-gradient(90deg,#f4f3fa 50%,#e0f7fa 100%)\">\n        \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">04 ▶ 化疗药物使用规范（培美曲塞＋卡铂）\u003C/h2>\n      \u003C/div>\n      \u003Cdiv class=\"lung-drug-guide-content\">\n        \u003Cp>\n          \u003Cb>培美曲塞 Pemetrexed\u003C/b>和\u003Cb>卡铂 Carboplatin\u003C/b>是经典的联合化疗方案。主要通过抑制DNA复制和细胞分裂实现作用。\n        \u003C/p>\n        \u003Cul>\n          \u003Cli>\u003Cb>用药方式\u003C/b>：均为静脉注射，配套抗过敏和补充叶酸、维生素B12以减少副作用。\u003C/li>\n          \u003Cli>\u003Cb>化疗周期\u003C/b>：常见为3周一个周期，建议全疗程完成才能发挥最佳效果。\u003C/li>\n        \u003C/ul>\n        \u003Ch4>用药注意\u003C/h4>\n        \u003Cul>\n          \u003Cli>补充叶酸及维生素B12在用药前后进行，可明显降低骨髓抑制等风险。\u003C/li>\n          \u003Cli>每周期检测血常规、肝肾功能，必要时根据白细胞降低调整剂量或延期用药。\u003C/li>\n        \u003C/ul>\n        \u003Ch4>药物相互作用\u003C/h4>\n        \u003Cul>\n          \u003Cli>服用NSAIDs（如布洛芬）时要谨慎，可延长培美曲塞在体内的作用时间，增加毒性。\u003C/li>\n          \u003Cli>卡铂与其他已知肾毒性药物联用会增加肾损伤风险。\u003C/li>\n        \u003C/ul>\n        \u003Ch4>常见不良反应及处理 \u003Cspan class=\"emoji\">❗\u003C/span>\u003C/h4>\n        \u003Cul>\n          \u003Cli>恶心、呕吐、食欲不振：需联合止吐药进行预防与处理。\u003C/li>\n          \u003Cli>脱发、皮肤色素沉着：通常停止用药后可恢复。\u003C/li>\n          \u003Cli>骨髓抑制：表现为贫血、感染易感，建议规律监测血常规。\u003C/li>\n        \u003C/ul>\n        \u003Ch4>特殊用药人群\u003C/h4>\n        \u003Cul>\n          \u003Cli>严重肝肾功能不全者禁用。\u003C/li>\n        \u003C/ul>\n        \u003Ch4>储存与过期管理\u003C/h4>\n        \u003Cul>\n          \u003Cli>药物粉针需避光密封，常温保存。\u003C/li>\n          \u003Cli>开瓶后或稀释后应按说明快速用完，不可反复使用剩药。\u003C/li>\n        \u003C/ul>\n        \u003Cdiv class=\"lung-drug-guide-case\">\n          \u003Cp>\n            \u003Cspan class=\"emoji\">💡\u003C/span> 临床上有患者按周期规律化疗，并补充维生素B12、叶酸，整体耐受性良好，应对不良反应较为顺利。\n          \u003C/p>\n        \u003C/div>\n        \u003Cp class=\"lung-drug-guide-ref\">\n          参考文献：Scagliotti, G.V. et al., \"Phase III Study Comparing Cisplatin Plus Gemcitabine with Cisplatin Plus Pemetrexed in Chemotherapy-Naive Patients with Advanced-Stage Non–Small-Cell Lung Cancer,\" JCO, 2008.\n        \u003C/p>\n      \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"lung-drug-guide-section\">\n    \u003Cdiv class=\"lung-drug-guide-title\" style=\"background:linear-gradient(90deg,#f8f3e3 60%,#e3f6f8 100%)\">\n      \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">05 ▶ 骨保护药品（双膦酸盐）安全用药要诀\u003C/h2>\n    \u003C/div>\n    \u003Cdiv class=\"lung-drug-guide-content\">\n      \u003Cp>\n        \u003Cb>双膦酸盐\u003C/b>类药物（如唑来膦酸 Zoledronic acid）用于保护骨骼不被异常吸收。它通过抑制破骨细胞活性，减缓骨量流失速度。\n      \u003C/p>\n      \u003Cul>\n        \u003Cli>\u003Cb>给药方法\u003C/b>：多为静脉滴注，通常每3-4周一次。\u003C/li>\n        \u003Cli>\u003Cb>用药前准备\u003C/b>：开始用药前建议补充足量维生素D和钙。\u003C/li>\n      \u003C/ul>\n      \u003Ch4>常见副作用\u003C/h4>\n      \u003Cul>\n        \u003Cli>一过性发热、肌肉酸痛。\u003C/li>\n        \u003Cli>偶见肾功能损害，用药前后需充足补液并密切监测肾功能。\u003C/li>\n        \u003Cli>罕见颌骨坏死，牙齿有问题时应停药并请口腔科会诊。\u003C/li>\n      \u003C/ul>\n      \u003Ch4>禁忌与注意事项\u003C/h4>\n      \u003Cul>\n        \u003Cli>有严重肾功能损害（肌酐清除率<30ml/min）者禁用。\u003C/li>\n        \u003Cli>静脉滴注期间须慢速输入，监测反应。\u003C/li>\n      \u003C/ul>\n      \u003Ch4>储存条件\u003C/h4>\n      \u003Cul>\n        \u003Cli>需保持密封避光，室温保存。\u003C/li>\n        \u003Cli>开封后未用尽的药品不可留作下次使用。\u003C/li>\n      \u003C/ul>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"lung-drug-guide-section\">\n    \u003Cdiv class=\"lung-drug-guide-title\" style=\"background:linear-gradient(90deg,#e4eaf8 60%,#e9f8e3 100%)\">\n      \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">06 ▶ 用药过程中的常见疑问与处理\u003C/h2>\n    \u003C/div>\n    \u003Cdiv class=\"lung-drug-guide-content\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cb>漏服/漏打怎么办？\u003C/b> 遇到漏服靶向药物，通常按说明处理，尽快补服但从不加倍。注射品需电话联系医务人员协助登记和调整下一个用药时间。\n        \u003C/li>\n        \u003Cli>\n          \u003Cb>怀疑药品变质该如何处置？\u003C/b> 变色、异味或说明书过期不得使用，不得带回家自行保存过期药，应交由专业回收处理。\n        \u003C/li>\n        \u003Cli>\n          \u003Cb>药物过量误服如何急救？\u003C/b> 若有明显不良反应建议立刻就诊，不可等待症状自行改善，每个药品的急救措施略有不同（如催吐、洗胃等均需专业评估）。\n        \u003C/li>\n        \u003Cli>\n          \u003Cb>联合用药时有不适需立即报告吗？\u003C/b> 是的，出现突发过敏、呼吸困难、高热等情况，务必随时通知医护人员。\n        \u003C/li>\n      \u003C/ul>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"lung-drug-guide-section\">\n    \u003Cdiv class=\"lung-drug-guide-title\" style=\"background:linear-gradient(90deg,#ffe2e2 60%,#e2f7ff 100%)\">\n      \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">07 ▶ 结语与关键提醒\u003C/h2>\n    \u003C/div>\n    \u003Cdiv class=\"lung-drug-guide-content\">\n      \u003Cp>\n        本文梳理了针对常用靶向药、免疫抑制剂、化疗药与骨保护剂的核心用药细节与注意事项。\n      \u003C/p>\n      \u003Cul>\n        \u003Cli>\n          靶向药与免疫药物组合时，不能自行增减剂量，不可随意调整用药时间。\n        \u003C/li>\n        \u003Cli>\n          定期复查和实验室监测，是发现潜在用药风险的有效方式。\n        \u003C/li>\n        \u003Cli>\n          任何怀疑药物不良反应或用药困惑，第一时间联系专业医生。\u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        合理用药，让治疗效果事半功倍。家人朋友如有相关需要，也记得提醒他们关注这些用药细节。\n      \u003C/p>\n    \u003C/div>\n  \u003C/div>  \n\n  \u003Cdiv class=\"lung-drug-guide-section\">\n    \u003Cdiv class=\"lung-drug-guide-title\" style=\"background:linear-gradient(90deg,#eaf6ff 50%,#ffede3 100%)\">\n      \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">参考文献\u003C/h2>\n    \u003C/div>\n    \u003Cdiv class=\"lung-drug-guide-content\">\n      \u003Col>\n        \u003Cli>Long, G.V. et al., Dabrafenib and Trametinib Combination Therapy for Patients with BRAF-mutant Metastatic Melanoma: Long-term Survival in Phase II/III trials, Annals of Oncology, 2017.\u003C/li>\n        \u003Cli>Reck, M. et al., Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer, New England Journal of Medicine, 2016.\u003C/li>\n        \u003Cli>Scagliotti, G.V. et al., Phase III Study Comparing Cisplatin Plus Gemcitabine with Cisplatin Plus Pemetrexed in Chemotherapy-Naive Patients with Advanced-Stage Non–Small-Cell Lung Cancer, Journal of Clinical Oncology, 2008.\u003C/li>\n      \u003C/ol>\n    \u003C/div>\n  \u003C/div>\n\u003C/div>\n\n\u003Cstyle>\n.lung-drug-guide-container {\n  font-family: \"PingFang SC\", \"微软雅黑\", \"Arial\", sans-serif;\n  max-width: 700px;\n  margin: 30px auto;\n  background: #fafbfc;\n  border-radius: 12px;\n  box-shadow: 0 2px 12px rgba(49,76,102,.06);\n  padding: 30px 28px 24px 28px;\n  color: #24292f;\n}\n\n.lung-drug-guide-header {\n  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06:50:00",2,[34],{"menuId":35,"menuName":36,"parentId":21,"orderNum":32,"path":37,"component":38,"isFrame":39,"isCache":40,"menuType":41,"visible":42,"status":21,"createDept":6,"remark":23,"createTime":43,"children":44,"columnImage":45,"columnLogo":46,"uncheckedLogo":6,"checkedLogo":6,"isHot":42,"isHome":21,"forceLogin":21,"color":47,"seoTitle":48,"seoKeywords":49,"seoDescription":50,"contentNum":6,"promotionalPoster":51,"menuFrame":7,"innerLink":7,"parentView":7,"routeName":52,"routerPath":37,"componentInfo":38},"1986713082609147906","健康科普","article","/article.html","1","0","T",1,"2025-11-07 16:31:25",[],"https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:49/d4291d16-ed1c-48dd-84c8-ec1f85980b75.png","https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:52/6fe64094-9416-442c-a66d-032fb292666a.png","#c8e6ca","健康科普助力健康中国2030:共享健康知识新理念","健康科普, 健康中国, 科普知识, 健康家庭, 性健康, 营养健康, 运动健康, 科普宣传","探索健康科普在健康中国行动中的重要角色,了解最新的健康科普创新大赛、动漫及短视频,传播健康知识,助力全民健康。","https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:56/bd33f471-6c54-4d1b-a364-b06973dbc144.png","Article","癌症肿瘤,重大疾病",true,{"code":9,"msg":10,"message":6,"data":56,"success":54},{"pageNo":42,"pageSize":57,"result":58,"totalSize":21},10,[],{"code":9,"msg":10,"message":6,"data":60,"success":54},{"authors":61,"appraiseDimensionScoresVos":62},[],[]]