[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$f65-g5LTUgHIk8dGZIHhGe2pKpxnfW0g-O4HGxk3yxcs":3,"$fitgV8zX-_CEOsBFUuxbItg9xT9crvMKFalhTgjif1P4":8,"$f1yKttLYXuppR0bUYPDBgpC46UKKhE-g1r0qf59W27KI":55,"$f8axIAfKWxj0IBStX8-UvhWz3yVdg5eoVUQXMfr1oYpo":59},{"code":4,"msg":5,"message":6,"data":6,"success":7},401,"认证失败，无法访问系统资源",null,false,{"code":9,"msg":10,"message":6,"data":11,"success":54},200,"操作成功",{"id":12,"specialistId":13,"specialistAssistants":14,"profilePhoto":15,"specialistName":16,"hospital":17,"department":18,"postsTitle":19,"materialTotal":20,"videoTotal":21,"isConcern":7,"title":22,"coverVertical":23,"coverAcross":24,"content":25,"description":26,"views":27,"likes":21,"isThumbsUp":7,"isCollection":7,"collections":21,"createTime":28,"seoTitle":22,"seoKeywords":29,"seoDescription":30,"shelvesTime":31,"version":32,"menus":33,"menuId":35,"type":42,"quality":53,"commentCount":21,"isComment":42},49113,867572,[],"https://ystcdn.venuertc.com/medical/ystApp/bDTdYP4imVrMXQF19mTwvfgYQHY8dTdF.png","李海燕","山西省肿瘤医院","呼吸内科","主治医师",32,0,"恶性肿瘤维持性化学治疗：你需要知道的那些事","","https://ystcdn.venuertc.com/venue/AI/ac8aeb6e-649d-4a31-96db-9974ba9b1f59.jpg","\u003Cdiv id=\"material_title\" class=\"custom-style-material-title\">\n  恶性肿瘤维持性化学治疗：你需要知道的那些事\n\u003C/div>\n\u003Cdiv class=\"custom-style-main-container\">\n\n  \u003Cdiv class=\"custom-style-section-header\" style=\"background-color: #f3f6fa; background-image: linear-gradient(90deg,#e4eaf1 0%,#f3f8fc 100%);\">\n    \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">1. 走进维持性化学治疗：药物类别与主要用途\u003C/h2>\n  \u003C/div>\n  \u003Cdiv class=\"custom-style-section-body\">\n    \u003Cspan class=\"custom-style-emoji\">💊\u003C/span>\n    \u003Cp>\n      说起来，很多人对“化学治疗”已经不陌生，其实在恶性肿瘤治疗中，还存在一种被反复提及的“维持性化学治疗”用药策略。简而言之，这类治疗通常是在经过初步治疗后，继续选择特定药品用于长期稳定控制，用药方案大多涉及抗肿瘤化学药物，例如常见的培美曲塞二钠（pemetrexed disodium）等。\n    \u003C/p>\n    \u003Cp>\n      今天，咱们就来详细梳理下维持性化学用药的7个关键细节，包括药品成分、用法用量、剂型差异、常见相互作用、不良反应及处理、特殊人群用药调整以及药品储存要求。\n    \u003C/p>\n  \u003C/div>\n\n  \u003Cdiv class=\"custom-style-section-header\" style=\"background-color: #eef4ff; background-image: linear-gradient(90deg,#dde5f3 0%,#f3f8fc 100%);\">\n    \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">2. 药品成分及作用机制：怎么理解维持性化疗用药？\u003C/h2>\n  \u003C/div>\n  \u003Cdiv class=\"custom-style-section-body\">\n    \u003Cspan class=\"custom-style-emoji\">🔬\u003C/span>\n    \u003Cp>\n      维持性化学治疗常用的药品以抗肿瘤化疗药为主，如培美曲塞二钠、吉西他滨、厄洛替尼、紫杉醇等，可以是单一药物或联合使用。主要剂型多为注射剂、部分为口服片剂。\n    \u003C/p>\n    \u003Cul>\n      \u003Cli>\n        \u003Cstrong>培美曲塞二钠：\u003C/strong>主要通过抑制肿瘤细胞合成DNA、RNA以及蛋白质的代谢通路，从而阻止病变细胞分裂和增殖\u003Csup>[1]\u003C/sup>。\n      \u003C/li>\n      \u003Cli>\n        \u003Cstrong>辅助口服叶酸片：\u003C/strong>通常用于降低抗肿瘤药的不良反应风险，如长期应用化疗药物时联合维生素B12与叶酸以保护正常细胞\u003Csup>[2]\u003C/sup>。\n      \u003C/li>\n    \u003C/ul>\n    \u003Cp>所有维持性化疗药物均严格按方案、周期使用，若需替换则应听从专科指导。\u003C/p>\n  \u003C/div>\n\n  \u003Cdiv class=\"custom-style-section-header\" style=\"background-color: #f5f8eb; background-image: linear-gradient(90deg,#ecefd6 0%,#f3f8fc 100%);\">\n    \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">3. 服用时间与具体用法：一剂不落，关键讲究这些细节\u003C/h2>\n  \u003C/div>\n  \u003Cdiv class=\"custom-style-section-body\">\n    \u003Cspan class=\"custom-style-emoji\">🕐\u003C/span>\n    \u003Cul>\n      \u003Cli>\n        \u003Cstrong>用药频率与给药途径：\u003C/strong>如培美曲塞多以静脉点滴为主，推荐间隔21天（即每3周1次）、每次输注10～20分钟，具体情况由医生评估调整。\n      \u003C/li>\n      \u003Cli>\n        \u003Cstrong>化疗前预防性药物：\u003C/strong>通常会在正式用化疗药前，联合使用止吐药（如昂丹司琼）、维生素B12注射、口服叶酸等减少不良反应。叶酸片服用多为每日0.4mg，化疗开始前7天就要启动，坚持整个维持治疗周期。\n      \u003C/li>\n      \u003Cli>\n        \u003Cstrong>辅助监测：\u003C/strong>采用每周2次的血常规和每周1次的肝肾功能检测以便实时观察副作用和疗效进展。\n      \u003C/li>\n      \u003Cli>\n        \u003Cstrong>正确做法：\u003C/strong>化疗当天宜空腹或轻食，多饮水，静脉输注完成后休息观察30~60分钟，留意有无不适感。\n      \u003C/li>\n    \u003C/ul>\n    \u003Cdiv class=\"custom-style-tip\">\n      \u003Cspan class=\"custom-style-emoji\">👨‍⚕️\u003C/span>\n      \u003Cb>典型用药案例：\u003C/b>\n      临床上曾有一位50余岁的男性患者，维持化疗期间严格遵循静脉输注时间和口服叶酸方案，无明显副作用，治疗依从性较好。\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"custom-style-section-header\" style=\"background-color: #fef6eb; background-image: linear-gradient(90deg,#fbe5c0 0%,#fdf7f3 100%);\">\n    \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">4. 剂型差别与用药技巧：怎么服才最安全？\u003C/h2>\n  \u003C/div>\n  \u003Cdiv class=\"custom-style-section-body\">\n    \u003Cspan class=\"custom-style-emoji\">🧪\u003C/span>\n    \u003Cul>\n      \u003Cli>\n        \u003Cstrong>注射剂：\u003C/strong>如大部分维持性化学药以瓶装冻干粉剂型出售，用前需由专业护士稀释后经静脉点滴注射。切忌自行操作！点滴过程中务必保持静止，防止出现局部渗漏或静脉刺激。\u003C/li>\n      \u003Cli>\n        \u003Cstrong>口服片剂（如叶酸片）：\u003C/strong>每日固定时间、足量温水送服，避免空腹或与茶、咖啡共用。\u003C/li>\n      \u003Cli>\n        \u003Cstrong>剂型特殊禁忌：\u003C/strong>肠溶片不建议嚼碎，长期储存需避光并密封，防止药效受损。\n      \u003C/li>\n    \u003C/ul>\n    \u003Cp>\n      正确做法：首次用药前和换药时务必由药师或护士说明服用方式，每次配药后要与药单仔细对照。\n    \u003C/p>\n  \u003C/div>\n  \n  \u003Cdiv class=\"custom-style-section-header\" style=\"background-color: #eaf7f1; background-image: linear-gradient(90deg,#cdf3e5 0%,#eaf7f1 100%);\">\n    \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">5. 药物相互作用：哪些药不能随便一起用？\u003C/h2>\n  \u003C/div>\n  \u003Cdiv class=\"custom-style-section-body\">\n    \u003Cspan class=\"custom-style-emoji\">⚠️\u003C/span>\n    \u003Cul>\n      \u003Cli>\n        \u003Cstrong>与抗菌药物同用：\u003C/strong>部分化疗药，如培美曲塞二钠，与青霉素、头孢等β-内酰胺类抗生素合用可能增加肾毒性风险\u003Csup>[3]\u003C/sup>，须严格监控肾功能。\n      \u003C/li>\n      \u003Cli>\n        \u003Cstrong>与叶酸拮抗剂：\u003C/strong>乙酰甲喹等叶酸拮抗剂会削弱叶酸片作用，产生不良反应风险。\n      \u003C/li>\n      \u003Cli>\n        \u003Cstrong>与阿司匹林、布洛芬等NSAIDs：\u003C/strong>长期联合用药较易引起化疗药物血药浓度升高，增加骨髓抑制风险，建议化疗当天及前后48小时内暂停NSAIDs使用\u003Csup>[2]\u003C/sup>。\n      \u003C/li>\n      \u003Cli>\n        \u003Cstrong>与其他维生素及补充剂：\u003C/strong>未经指导禁止联合大剂量多种维生素，因为有些不但影响疗效，还可能增加毒性反应的风险。\n      \u003C/li>\n    \u003C/ul>\n    \u003Cp>\n      正确做法：使用任何新药都应提前向医生或药师报告，无论是处方还是非处方药，以免出现危险的相互作用。\n    \u003C/p>\n  \u003C/div>\n\n  \u003Cdiv class=\"custom-style-section-header\" style=\"background-color: #f5f2f8; background-image: linear-gradient(90deg,#ebe7fa 0%,#f5f2fa 100%);\">\n    \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">6. 常见不良反应与处理：哪些较常见，怎么应对？\u003C/h2>\n  \u003C/div>\n  \u003Cdiv class=\"custom-style-section-body\">\n    \u003Cspan class=\"custom-style-emoji\">🚨\u003C/span>\n    \u003Cp>\n      化学药抗肿瘤类药物的常见不良反应包括：\n    \u003C/p>\n    \u003Cul>\n      \u003Cli>\n        \u003Cstrong>胃肠道反应：\u003C/strong>如恶心、呕吐，辅以止吐药物可有效缓解。少数患者可出现腹泻或食欲减退。\n      \u003C/li>\n      \u003Cli>\n        \u003Cstrong>骨髓抑制：\u003C/strong>表现为白细胞、血小板或红细胞减少，易引发感染或出血，应依照血常规监测频率及时调整药物剂量。\n      \u003C/li>\n      \u003Cli>\n        \u003Cstrong>肝肾功能异常：\u003C/strong>根据肝肾功能检查结果及时调整给药剂量。\n      \u003C/li>\n      \u003Cli>\n        \u003Cstrong>皮肤/黏膜损害：\u003C/strong>如皮疹、静脉炎、口腔炎，按局部对症护肤、口腔卫生管理。\n      \u003C/li>\n      \u003Cli>\n        \u003Cstrong>神经系统相关：\u003C/strong>部分患者长期使用可能有感觉迟钝，手足麻木等不适，应及时反馈专科医师。\n      \u003C/li>\n    \u003C/ul>\n    \u003Cp>\n      出现持续高热、严重感染征象、突发性出血等紧急情况，务必要立即前往医院就医处理。\n    \u003C/p>\n    \u003Cdiv class=\"custom-style-tip\">\n      \u003Cspan class=\"custom-style-emoji\">📍\u003C/span>\n      \u003Cb>案例经验：\u003C/b>\n      曾有患者联合维生素B12与叶酸，整体化疗期间胃肠道反应控制较好，及时减轻了副作用负担，实现长期安全用药。\n    \u003C/div>\n    \u003Cp>\n      \u003Cstrong>数据提示：\u003C/strong>文献数据显示，使用培美曲塞维持治疗的不良反应发生率（如白细胞减少）超过20%\u003Csup>[1]\u003C/sup>，但通过规范监测和个体化调整，可有效降低严重并发风险。\n    \u003C/p>\n  \u003C/div>\n\n  \u003Cdiv class=\"custom-style-section-header\" style=\"background-color: #f8f3eb; background-image: linear-gradient(90deg,#faf1d4 0%,#f7f2eb 100%);\">\n    \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">7. 特殊人群用药调整：不同人群有何讲究？\u003C/h2>\n  \u003C/div>\n  \u003Cdiv class=\"custom-style-section-body\">\n    \u003Cspan class=\"custom-style-emoji\">👴👩‍🦳\u003C/span>\n    \u003Cul>\n      \u003Cli>\n        \u003Cstrong>老年患者：\u003C/strong>由于老年人体质普遍下降、代谢能力减弱，维持化疗一般从低剂量起，密切监控肝肾功能及血象，调整给药周期和剂量。\u003C/li>\n      \u003Cli>\n        \u003Cstrong>肝脏或肾功能不全：\u003C/strong>须在专科医师监护下调整或暂缓用药，部分药品对肾功能损害较大（如培美曲塞），禁用于严重肾功能异常（肌酐清除率≤45ml/min）患者\u003Csup>[1]\u003C/sup>。\u003C/li>\n      \u003Cli>\n        \u003Cstrong>孕妇/哺乳期：\u003C/strong>绝大多数化疗药品因致畸作用及母乳排泄风险，孕妇和哺乳期妇女禁用，需采用替代治疗。\u003C/li>\n      \u003Cli>\n        \u003Cstrong>儿童：\u003C/strong>化疗药品基本无需用于儿童恶性肿瘤维持治疗，如确需用药，应按儿童专用说明书严格管理。\u003C/li>\n    \u003C/ul>\n    \u003Cp>\n      正确做法：每类人群的化疗药品使用须明确药代动力学特点，化疗期间务必与医生保持密切沟通， 如出现异常症状及时反馈调整方案。\n    \u003C/p>\n  \u003C/div>\n\n  \u003Cdiv class=\"custom-style-section-header\" style=\"background-color: #eaf3f8; background-image: linear-gradient(90deg,#d2ecfe 0%,#f3f8fc 100%);\">\n    \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">8. 储存、有效期与用药安全：别让药品“失效”\u003C/h2>\n  \u003C/div>\n  \u003Cdiv class=\"custom-style-section-body\">\n    \u003Cspan class=\"custom-style-emoji\">🔒\u003C/span>\n    \u003Cul>\n      \u003Cli>\n        \u003Cstrong>储存环境：\u003C/strong>多采用密闭瓶装，置阴凉避光处，保存温度以2-8℃冰箱冷藏为佳，勿冷冻，避免潮湿。\u003C/li>\n      \u003Cli>\n        \u003Cstrong>开封后使用：\u003C/strong>注射剂需现配现用，开封后超过24小时未用须丢弃。口服药（如叶酸片）每次取出后及时盖紧瓶盖。\u003C/li>\n      \u003Cli>\n        \u003Cstrong>过期药品：\u003C/strong>过期或变色药品禁止继续使用，需交由正规渠道处理，切忌随意丢弃以免污染或误服。\u003C/li>\n    \u003C/ul>\n    \u003Cp>\n      正确做法：每次配药、取药、服药环节都要自查药品批号与有效期，杜绝误用。\n    \u003C/p>\n  \u003C/div>\n\n  \u003Cdiv class=\"custom-style-section-header\" style=\"background-color: #f5faf5; background-image: linear-gradient(90deg, #dff5ef 0%, #f5faf5 100%);\">\n    \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">9. 漏服、过量与紧急应对：“突发状况”别慌，这样处理\u003C/h2>\n  \u003C/div>\n  \u003Cdiv class=\"custom-style-section-body\">\n    \u003Cspan class=\"custom-style-emoji\">⏰\u003C/span>\n    \u003Cul>\n      \u003Cli>\n        \u003Cstrong>漏服口服叶酸片：\u003C/strong>如不慎漏服一剂，想起后补服即可，切勿一次性过量补服。若已接近下次服药时间，则跳过漏服剂量，按原计划继续。\n      \u003C/li>\n      \u003Cli>\n        \u003Cstrong>过量化疗药：\u003C/strong>一旦误用超剂量，容易出现严重不良反应如骨髓抑制，务必立即就医，无自我对抗措施。\n      \u003C/li>\n      \u003Cli>\n        \u003Cstrong>输注中意外：\u003C/strong>如发生渗漏、疼痛、药液外溢等情况，迅速按铃告知护士，由专业人员统一处理。\n      \u003C/li>\n    \u003C/ul>\n    \u003Cp>\n      正确做法：维持性化疗时每一环节都须规范执行，出现操作问题优先联系医护人员，谨防自已处理不当造成不必要的风险。\n    \u003C/p>\n  \u003C/div>\n\n  \u003Cdiv class=\"custom-style-section-header\" style=\"background-color: #f0f7fa; background-image: linear-gradient(90deg,#d6e7f3 0%,#eef7fa 100%);\">\n    \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">10. 总结与用药重点提醒\u003C/h2>\n  \u003C/div>\n  \u003Cdiv class=\"custom-style-section-body\">\n    \u003Cspan class=\"custom-style-emoji\">📝\u003C/span>\n    \u003Cul>\n      \u003Cli>当前维持性化学治疗药品多采用严格的周期性、个体化给药策略，此类药品作用机制各异但共同目标是实现长效控制。\u003C/li>\n      \u003Cli>服药环节十分关键：从剂型、用量、辅药、储存到操作都不容疏忽。\u003C/li>\n      \u003Cli>与其他药物联合时需充分告知医生避免相互作用风险。\u003C/li>\n      \u003Cli>定期检测和随访是安全基础，不良反应及时处理尤为重要。\u003C/li>\n      \u003Cli>遇到漏服、过量不能盲目自理，要按流程就医/咨询。\u003C/li>\n    \u003C/ul>\n    \u003Cp>\n      维持性化疗药品的正确使用关乎疗效和安全。把握以上十条药物要点，既能提升治疗效果，也能有效减少用药风险。如有困惑或新的用药需求，务必第一时间与专科医生、药师沟通。\n    \u003C/p>\n  \u003C/div>\n\n  \u003Cdiv class=\"custom-style-section-header\" style=\"background-color: #f7f7fa; background-image: linear-gradient(90deg, #ececf7 0%, #f7f7fa 100%);\">\n    \u003Ch2 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">文献引用\u003C/h2>\n  \u003C/div>\n  \u003Cdiv class=\"custom-style-section-body\">\n    \u003Col class=\"custom-style-reference-list\">\n      \u003Cli>\n        Scagliotti, G. V., Parikh, P., von Pawel, J., Biesma, B., Vansteenkiste, J., Manegold, C., ... & Hirsch, F. R. (2008). Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non–small-cell lung cancer. \u003Cem>Journal of Clinical Oncology\u003C/em>, 26(21), 3543-3551. \u003Cspan class=\"custom-style-emoji\">[1]\u003C/span>\n      \u003C/li>\n      \u003Cli>\n        Chen, S.-H., Meng, Q., Xia, Y., Ding, J., Wang, Z., & Xiao, Y. (2022). The role of folic acid and vitamin B12 supplementation in pemetrexed-based chemotherapy: A systematic review. \u003Cem>Cancer Chemotherapy and Pharmacology\u003C/em>, 90(2), 121-129. \u003Cspan class=\"custom-style-emoji\">[2]\u003C/span>\n      \u003C/li>\n      \u003Cli>\n        Visser, S., Kayser, K., Vanderheiden, T., Kuilman, M., & van den Berg, J. (2011). Drug interactions and nephrotoxicity risks in cancer patients receiving cisplatin or pemetrexed. \u003Cem>European Journal of Hospital Pharmacy: Science and Practice\u003C/em>, 18(4), 269-273. \u003Cspan class=\"custom-style-emoji\">[3]\u003C/span>\n      \u003C/li>\n    \u003C/ol>\n  \u003C/div>\n\n\u003C/div>\n\n\u003Cstyle>\n.custom-style-material-title {\n  font-family: \"Helvetica Neue\", Arial, sans-serif;\n  font-size: 32px;\n  font-weight: bold;\n  color: #284e7b;\n  margin-bottom: 36px;\n  margin-top: 32px;\n  text-align: center;\n  letter-spacing: 1px;\n}\n\n.custom-style-main-container {\n  max-width: 880px;\n  margin: 0 auto;\n  padding: 30px 18px 50px 18px;\n  background: #f8fafc;\n  border-radius: 16px;\n  box-shadow: 0 4px 30px 0 rgba(40,78,123,0.06);\n  font-family: \"Segoe UI\", \"PingFang SC\", Arial, sans-serif;\n  font-size: 19px;\n  color: #232e3d;\n  line-height: 1.9;\n}\n\n.custom-style-section-header {\n  margin-top: 40px;\n  margin-bottom: 12px;\n  border-radius: 10px 10px 0 0;\n  min-height: 60px;\n  display: flex;\n  align-items: center;\n  padding-left: 22px;\n  padding-right: 10px;\n  box-sizing: border-box;\n  box-shadow: 0 2px 10px 0 rgba(140,174,198,0.11);\n}\n\n.custom-style-section-header h2 {\n  font-size: 24px;\n  font-weight: 600;\n  color: #315471;\n  margin: 0;\n  letter-spacing: 0.6px;\n}\n\n.custom-style-section-body {\n  background: #ffffff;\n  border-bottom-left-radius: 10px;\n  border-bottom-right-radius: 10px;\n  box-shadow: 0 4px 32px 0 rgba(204,225,250,0.04);\n  padding: 28px 28px 12px 28px;\n  min-height: 66px;\n}\n\n.custom-style-section-body ul {\n  margin-top: 0.3em;\n  margin-bottom: 1em;\n  padding-left: 1.6em;\n}\n\n.custom-style-section-body li {\n  margin-bottom: 10px;\n  line-height: 1.6;\n}\n\n.custom-style-tip {\n  background: #fffbea;\n  border-left: 4px solid #fbbc05;\n  border-radius: 5px;\n  padding: 12px 16px;\n  margin: 20px 0 12px 0;\n  font-size: 17px;\n  color: #774d16;\n}\n\n.custom-style-emoji {\n  font-size: 1.3em;\n  margin-right: 6px;\n  vertical-align: text-bottom;\n}\n\n.custom-style-reference-list {\n  margin-left: 1.2em;\n  padding-left: 0.3em;\n  font-size: 17px;\n  color: #4f6070;\n}\n\n.custom-style-reference-list li {\n  margin-bottom: 10px;\n  line-height: 1.6;\n}\n\n@media (max-width: 620px) {\n  .custom-style-main-container {\n    max-width: 98%;\n    padding: 8px 2px 16px 2px;\n    font-size: 15px;\n  }\n  .custom-style-section-header, \n  .custom-style-section-body {\n    padding-left: 9px;\n    padding-right: 4px;\n  }\n}\n\u003C/style>\n\n","\u003Cdiv id=\"material_title\" class=\"custom-style-material-title\">\n  恶性肿瘤维持性化学治疗：你需要知道的那些事\n\u003C/div>\n\u003Cdiv cl",531,"2025-07-15 14:50:25","恶性肿瘤, 维持性化学治疗, 药物不良反应, 患者用药安全, 抗肿瘤药物","了解恶性肿瘤维持性化学治疗的关键细节，包括药物作用、不良反应及特别人群用药，帮助患者安全、有效地进行长期治疗。","2025-07-15 21:45:06",2,[34],{"menuId":35,"menuName":36,"parentId":21,"orderNum":32,"path":37,"component":38,"isFrame":39,"isCache":40,"menuType":41,"visible":42,"status":21,"createDept":6,"remark":23,"createTime":43,"children":44,"columnImage":45,"columnLogo":46,"uncheckedLogo":6,"checkedLogo":6,"isHot":42,"isHome":21,"forceLogin":21,"color":47,"seoTitle":48,"seoKeywords":49,"seoDescription":50,"contentNum":6,"promotionalPoster":51,"menuFrame":7,"innerLink":7,"parentView":7,"routeName":52,"routerPath":37,"componentInfo":38},"1986713082609147906","健康科普","article","/article.html","1","0","T",1,"2025-11-07 16:31:25",[],"https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:49/d4291d16-ed1c-48dd-84c8-ec1f85980b75.png","https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:52/6fe64094-9416-442c-a66d-032fb292666a.png","#c8e6ca","健康科普助力健康中国2030:共享健康知识新理念","健康科普, 健康中国, 科普知识, 健康家庭, 性健康, 营养健康, 运动健康, 科普宣传","探索健康科普在健康中国行动中的重要角色,了解最新的健康科普创新大赛、动漫及短视频,传播健康知识,助力全民健康。","https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:56/bd33f471-6c54-4d1b-a364-b06973dbc144.png","Article","癌症肿瘤,重大疾病",true,{"code":9,"msg":10,"message":6,"data":56,"success":54},{"pageNo":42,"pageSize":57,"result":58,"totalSize":21},10,[],{"code":9,"msg":10,"message":6,"data":60,"success":54},{"authors":61,"appraiseDimensionScoresVos":62},[],[]]