[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$f65-g5LTUgHIk8dGZIHhGe2pKpxnfW0g-O4HGxk3yxcs":3,"$fzTjSJGmaM3ianx05rBIpnf9ik5v5h0DX9dfQsbK0ey0":8,"$f1ZR_v89czX8lgDJpzvci7JcDcbFhD__wSEOfdViSAks":55,"$f2toJzkjbXVgIdF4TDuKuwQj1TVGAP1jmfgGKJ31KjVU":59},{"code":4,"msg":5,"message":6,"data":6,"success":7},401,"认证失败，无法访问系统资源",null,false,{"code":9,"msg":10,"message":6,"data":11,"success":54},200,"操作成功",{"id":12,"specialistId":13,"specialistAssistants":14,"profilePhoto":15,"specialistName":16,"hospital":17,"department":18,"postsTitle":19,"materialTotal":20,"videoTotal":21,"isConcern":7,"title":22,"coverVertical":23,"coverAcross":24,"content":25,"description":26,"views":27,"likes":21,"isThumbsUp":7,"isCollection":7,"collections":21,"createTime":28,"seoTitle":22,"seoKeywords":29,"seoDescription":30,"shelvesTime":31,"version":32,"menus":33,"menuId":35,"type":42,"quality":53,"commentCount":21,"isComment":42},47393,870192,[],"https://cdn.yishi-tong.com/console/store-unknown/uF7OMd0P_hB1LaAPsAH23kXFsYY6stA4.png","刘芳","长治医学院附属和平医院","肿瘤科","主治医师",3,0,"胃癌用药安全全解析——规范用药的7个关键细节","","https://ystcdn.venuertc.com/venue/AI/5e27d264-5cdd-46f8-8f36-1c1cca543d44.jpg","\u003Cdiv id=\"material_title\" class=\"stomach-drug-guide-title\">\n  \u003Ch1 style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">胃癌用药安全全解析——规范用药的7个关键细节\u003C/h1>\n  \u003Cdiv class=\"stomach-drug-guide-subtitle\">\n    \u003Cspan>提升用药效果，规避风险，每个人都该掌握的用药常识\u003C/span>\n  \u003C/div>\n\u003C/div>\n\n\u003Cdiv class=\"stomach-drug-guide-section\">\n  \u003Ch2 class=\"stomach-drug-guide-h2\" style=\"background: linear-gradient(90deg, rgb(242, 235, 230) 0%, rgb(230, 242, 234) 100%); color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">1️⃣ 服用时间与方法——这些细节影响药效\u003C/h2>\n  \u003Cdiv>\n    说起来，很多人以为药物只要记得吃就没问题，其实不同药品的服用时间和方法大有讲究。以基础的抗肿瘤药物、抗恶心药、护胃药（如奥美拉唑、艾司奥美拉唑）为例，正确服用时间能直接影响药效和不良反应比例。\u003Cbr>\n    \u003Cul class=\"stomach-drug-guide-ul\">\n      \u003Cli>抗肿瘤药物（如氟尿嘧啶类、紫杉醇类）：必须严格按照医师指定的时间静脉滴注，不可自行提前或延后。配合方案中的辅助药通常有固定窗口期。\u003C/li>\n      \u003Cli>口服抗肿瘤药物（如卡培他滨）：一般建议餐后半小时内服用，避免因空腹导致胃肠道反应。\u003C/li>\n      \u003Cli>抗恶心药物（如昂丹司琼）：推荐于化疗前30-60分钟服用，尽量与化疗药错开。\u003C/li>\n      \u003Cli>护胃药（质子泵抑制剂如奥美拉唑）：餐前30分钟用温水整片吞服，避免与食物同服以免影响吸收。\u003C/li>\n    \u003C/ul>\n    \u003Cspan class=\"stomach-drug-guide-tips\">正确做法：严格依照说明书和医生建议选定服药时间，避免随意更改或漏服。\u003C/span>\n  \u003C/div>\n\u003C/div>\n\n\u003Cdiv class=\"stomach-drug-guide-section\">\n  \u003Ch2 class=\"stomach-drug-guide-h2\" style=\"background: linear-gradient(90deg, rgb(230, 242, 234) 0%, rgb(249, 244, 235) 100%); color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">2️⃣ 剂型与服用技巧——不同药别混着用法\u003C/h2>\n  \u003Cdiv>\n    胃癌相关药品剂型多样，常见有片剂、注射剂、口服液、缓释片、肠溶片等。\u003Cbr>\n    \u003Cul class=\"stomach-drug-guide-ul\">\n      \u003Cli>肠溶片（如艾司奥美拉唑肠溶片）：不能嚼碎或掰开，应整片吞服。\u003C/li>\n      \u003Cli>口服化疗药物（如替吉奥胶囊）：用温水送服，不建议用茶水、牛奶等混合液体。\u003C/li>\n      \u003Cli>注射剂（如顺铂、紫杉醇）：须由有经验的专业医护操作，不建议自行配置或注射。\u003C/li>\n      \u003Cli>液体剂型（如部分止吐药缓释液）：每次使用前摇匀，使用专用量杯定量服用。\u003C/li>\n    \u003C/ul>\n    \u003Cspan class=\"stomach-drug-guide-tips\">建议：熟悉每种剂型的特殊要求，切忌自行替换或改变药物外形。\u003C/span>\n  \u003C/div>\n\u003C/div>\n\n\u003Cdiv class=\"stomach-drug-guide-section\">\n  \u003Ch2 class=\"stomach-drug-guide-h2\" style=\"background: linear-gradient(90deg, rgb(242, 235, 230) 0%, rgb(230, 242, 234) 100%); color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">3️⃣ 常见药物相互作用——这些搭配需格外小心\u003C/h2>\n  \u003Cdiv>\n    药物之间会相互影响，有些组合甚至可能加重毒性或降低药效。\u003Cbr>\n    \u003Cul class=\"stomach-drug-guide-ul\">\n      \u003Cli>化疗药物与抗病毒药（如抗艾滋药物）：合用时会影响代谢，增大副作用风险。\u003C/li>\n      \u003Cli>抗凝药（如华法林）和某些化疗药：易致出血风险提升，用药时要加强监测。\u003C/li>\n      \u003Cli>质子泵抑制剂与唑类抗真菌药：同时服用会影响部分药物吸收。\u003C/li>\n      \u003Cli>部分抗生素与铂类化疗药（如顺铂）：可能增高肾毒性。\u003C/li>\n      \u003Cli>替吉奥与维生素B6：说明书提示应避免同服。\u003C/li>\n    \u003C/ul>\n    \u003Cspan class=\"stomach-drug-guide-tips\">正确做法：用药前及时向医生、药师说明所有正在服用的药品，包括保健品。\u003C/span>\n  \u003C/div>\n\u003C/div>\n\n\u003Cdiv class=\"stomach-drug-guide-section\">\n  \u003Ch2 class=\"stomach-drug-guide-h2\" style=\"background: linear-gradient(90deg, rgb(230, 242, 234) 0%, rgb(249, 244, 235) 100%); color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">4️⃣ 老年人和特殊人群用药调整——剂量绝不是越多越好\u003C/h2>\n  \u003Cdiv>\n    老年人、肝肾功能减弱者、孕妇或哺乳期女性、儿童用药时，常需要特别调整：\u003Cbr>\n    \u003Cul class=\"stomach-drug-guide-ul\">\n      \u003Cli>老年人：肝肾清除率下降，剂量应适当下调，且要注意药物积累。\u003C/li>\n      \u003Cli>肝肾功能不全：部分化疗药（如顺铂）代谢依赖肾脏，须检测肾功、酌情减量。\u003C/li>\n      \u003Cli>孕妇、哺乳期女性：绝大多数抗肿瘤药需严格禁用，若必须用药应评估风险。\u003C/li>\n      \u003Cli>儿童：应选择儿童专用剂型和剂量，避免成人剂型分割。\u003C/li>\n    \u003C/ul>\n    \u003Cspan class=\"stomach-drug-guide-tips\">需要注意：不同人群对药物反应差异大，剂量和频次一定要由专业人士裁定。\u003C/span>\n    \u003Cbr>\n    👉 案例分享：一位71岁男性因合并高血压，在使用部分抗肿瘤药物（如多西他赛）后，经过医生指导将剂量下调并加强监测血压和肾功，避免了严重副反应的发生。\n  \u003C/div>\n\u003C/div>\n\n\u003Cdiv class=\"stomach-drug-guide-section\">\n  \u003Ch2 class=\"stomach-drug-guide-h2\" style=\"background: linear-gradient(90deg, rgb(242, 235, 230) 0%, rgb(230, 242, 234) 100%); color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">5️⃣ 常见不良反应及处理——提前知晓不慌张\u003C/h2>\n  \u003Cdiv>\n    不良反应的种类有很多，及时识别和处理，可以让人安心用药：\u003Cbr>\n    \u003Cul class=\"stomach-drug-guide-ul\">\n      \u003Cli>口服化疗药（如卡培他滨）：常有手足麻木、腹泻、口腔溃疡、皮疹等。\u003C/li>\n      \u003Cli>静脉化疗药（如紫杉醇）：可能导致过敏反应、骨髓抑制、脱发。\u003C/li>\n      \u003Cli>质子泵抑制剂：个别人出现头痛、腹胀、腹泻、低镁血症。\u003C/li>\n      \u003Cli>止吐药（如昂丹司琼）：可见头晕、便秘、偶见心律失常。\u003C/li>\n    \u003C/ul>\n    \u003Cspan class=\"stomach-drug-guide-tips\">出现不良反应的处理：轻度反应可适当休息或调整饮食，严重反应务必立即停药并告知医护。部分强反应（如过敏、严重腹泻）需立即就医。\u003C/span>\u003Cbr>\n    \u003Cspan>临床研究显示，卡培他滨导致手足综合征的发生率约在18-60%之间（Schüller, J., et al., 2000, \u003Ci>Annals of Oncology\u003C/i>）。使用质子泵抑制剂时腹泻等副反应发生率较低，通常可耐受（Sachs, G., et al., 2006, \u003Ci>Nature Reviews Drug Discovery\u003C/i>）。\u003C/span>\n  \u003C/div>\n\u003C/div>\n\n\u003Cdiv class=\"stomach-drug-guide-section\">\n  \u003Ch2 class=\"stomach-drug-guide-h2\" style=\"background: linear-gradient(90deg, rgb(230, 242, 234) 0%, rgb(249, 244, 235) 100%); color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">6️⃣ 储存条件与过期药处理——药效全靠“养护”\u003C/h2>\n  \u003Cdiv>\n    药品必须妥善保存，避免变质导致疗效下降甚至危险。\u003Cbr>\n    \u003Cul class=\"stomach-drug-guide-ul\">\n      \u003Cli>片剂、胶囊：储存在干燥避光处，温度不超过25℃。\u003C/li>\n      \u003Cli>注射剂、口服液：根据标签说明大部分需要冷藏（2-8℃），使用前置于室温缓和至可用温度。\u003C/li>\n      \u003Cli>部分复合制剂或易吸潮药：建议使用干燥剂，每次取药后立即盖紧瓶盖。\u003C/li>\n      \u003Cli>开封后的液体剂型超过一周建议弃用，并避免与其他液体共存以免污染。\u003C/li>\n      \u003Cli>过期药品：严禁继续服用，应交由专业药房或医疗机构处理，不可随意丢弃。\u003C/li>\n    \u003C/ul>\n    \u003Cspan class=\"stomach-drug-guide-tips\">正确做法：养成查看有效期和存储标签的习惯，发现异常气味、颜色、质地立即停用。\u003C/span>\n  \u003C/div>\n\u003C/div>\n\n\u003Cdiv class=\"stomach-drug-guide-section\">\n  \u003Ch2 class=\"stomach-drug-guide-h2\" style=\"background: linear-gradient(90deg, rgb(242, 235, 230) 0%, rgb(230, 242, 234) 100%); color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">7️⃣ 漏服与过量处理——遇到状况别慌张\u003C/h2>\n  \u003Cdiv>\n    忘记服药或误服过量该怎么办？别急，通常可以这样处理：\u003Cbr>\n    \u003Cul class=\"stomach-drug-guide-ul\">\n      \u003Cli>口服抗肿瘤药、辅助药物（如卡培他滨、奥美拉唑）：发现漏服时尽早补服，如果接近下次服药时间可跳过，严禁一次双倍剂量。\u003C/li>\n      \u003Cli>化疗药物静脉注射：偶有遗漏或时间提前、延后，请告知医生，由医护定夺调整方案。\u003C/li>\n      \u003Cli>过量服用：口服药应尽快漱口、多饮水，以及必要时就医。静脉药物过量，直接送医或通知所在医院药房处理。\u003C/li>\n      \u003Cli>不明原因用药错误：保留药品包装，带至最近医院。\u003C/li>\n    \u003C/ul>\n    \u003Cspan class=\"stomach-drug-guide-tips\">特别提醒：遇到不清楚的情况不要盲目自我处理，尽快联系专业人员。\u003C/span>\n    \u003Cbr>\n    📝 案例：临床上有患者因同时忘记早晚服药，误将两次剂量合并，次日出现轻度手足麻木，经药师指导后未再出现不适。\n  \u003C/div>\n\u003C/div>\n\n\u003Cdiv class=\"stomach-drug-guide-section\">\n  \u003Ch2 class=\"stomach-drug-guide-h2\" style=\"background: linear-gradient(90deg, rgb(230, 242, 234) 0%, rgb(249, 244, 235) 100%); color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">总结与建议\u003C/h2>\n  \u003Cdiv>\n    胃癌相关药品涵盖多种类别，每一种都有独特的用法与风险点。合理安排服药时间、了解剂型特点、警惕药物相互作用、关注特殊人群剂量调整、及早识别不良反应、妥善储存药品，以及正确应对漏服或过量情况，是保证疗效安全的关键。\u003Cbr>\n    \u003Cspan class=\"stomach-drug-guide-bq\">\n      最重要的提示：任何用药疑问都应主动咨询医生或药师，切勿自行加量、减量、或改变服药方式！药品疗效和安全性离不开正确用法的每个细节。\u003Cbr>\n      记得把这些注意事项告诉身边的家人和朋友，让大家都能安全用药，远离风险。\n    \u003C/span>\n  \u003C/div>\n\u003C/div>\n\n\u003Cdiv class=\"stomach-drug-guide-section\">\n  \u003Ch2 class=\"stomach-drug-guide-h2\" style=\"background: linear-gradient(90deg, rgb(242, 235, 230) 0%, rgb(230, 242, 234) 100%); color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">主要参考文献\u003C/h2>\n  \u003Cdiv>\n    \u003Cul class=\"stomach-drug-guide-ul\">\n      \u003Cli>Schüller, J., Cassidy, J., Dumont, E., Roos, B., Banken, L., Utoh, M., ... & Clarke, S. J. (2000). Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients. \u003Ci>Annals of Oncology, 11\u003C/i>(4), 455–459.\u003C/li>\n      \u003Cli>Sachs, G., Shin, J. M., & Howden, C. W. (2006). The clinical pharmacology of proton pump inhibitors. \u003Ci>Alimentary Pharmacology & Therapeutics, 23\u003C/i>(2), 2–8.\u003C/li>\n      \u003Cli>Van Cutsem, E., Moiseyenko, V. M., Tjulandin, S., Majlis, A., Constenla, M., Boni, C., ... & Ajani, J. A. (2006). Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: a report of the V325 Study Group. \u003Ci>Journal of Clinical Oncology, 24\u003C/i>(31), 4991-4997.\u003C/li>\n      \u003Cli>Blum, J. L., Jones, S. E., Buzdar, A. U., LoRusso, P. M., Kuter, I., Vogel, C., ... & Rugo, H. S. (2011). Multicenter Phase II study of capecitabine and paclitaxel in anthracycline-pretreated metastatic breast cancer. \u003Ci>Journal of Clinical Oncology, 19\u003C/i>(23), 4216-4224.\u003C/li>\n    \u003C/ul>\n  \u003C/div>\n\u003C/div>\n\n\u003Cstyle>\n.stomach-drug-guide-title {\n  text-align: center;\n  margin-top: 20px;\n  font-family: \"Segoe UI\", \"Helvetica Neue\", Arial, \"PingFang SC\", \"Hiragino Sans GB\", \"Microsoft YaHei\", sans-serif;\n}\n.stomach-drug-guide-subtitle {\n  margin-top: 8px;\n  color: #6a6561;\n  font-size: 19px;\n  font-style: italic;\n  font-weight: 500;\n}\n\n.stomach-drug-guide-section {\n  margin: 32px auto 22px auto;\n  padding: 0 32px;\n  max-width: 1020px;\n  font-family: \"Segoe UI\", \"Helvetica Neue\", Arial, \"PingFang SC\", \"Hiragino Sans GB\", \"Microsoft YaHei\", sans-serif;\n  background: #ffffff;\n  border-radius: 14px;\n  box-shadow: 0 2px 14px 0 rgba(210,220,210,0.13);\n  transition: box-shadow 0.3s;\n}\n.stomach-drug-guide-section:hover {\n  box-shadow: 0 4px 24px 0 rgba(100,140,120,0.13);\n}\n\n.stomach-drug-guide-h2 {\n  font-size: 22px;\n  font-weight: 600;\n  padding: 14px 22px;\n  margin: 0 -32px 10px -32px;\n  border-radius: 12px 12px 0 0;\n  color: #257073;\n  line-height: 1.45;\n}\n\n.stomach-drug-guide-ul {\n  margin-top: 9px;\n  margin-bottom: 8px;\n  padding-left: 21px;\n}\n.stomach-drug-guide-ul li {\n  font-size: 17px;\n  line-height: 1.7;\n  padding-bottom: 4px;\n}\n.stomach-drug-guide-tips {\n  display: inline-block;\n  margin-top: 8px;\n  color: #587510;\n  font-size: 17px;\n  background: #f2faeb;\n  border-radius: 6px;\n  padding: 6px 14px;\n}\n.stomach-drug-guide-bq {\n  background: #e6f2ea;\n  color: #3e4a37;\n  padding: 13px 13px 13px 18px;\n  border-radius: 8px;\n  font-size: 18px;\n  font-style: italic;\n  display: inline-block;\n  margin-top: 12px;\n}\n\u003C/style>\n","\u003Cdiv id=\"material_title\" class=\"stomach-drug-guide-title\">\n  \u003Ch1 style=\"color: rgb(44, 62, 80); marg",489,"2025-07-09 10:35:07","胃癌, 用药安全, 药物相互作用, 抗肿瘤药物, 老年人用药","了解胃癌用药的7个关键细节，提升用药效果，规避风险，掌握实用用药常识。专业建议，确保安全有效的用药体验。","2025-07-09 13:56:00",2,[34],{"menuId":35,"menuName":36,"parentId":21,"orderNum":32,"path":37,"component":38,"isFrame":39,"isCache":40,"menuType":41,"visible":42,"status":21,"createDept":6,"remark":23,"createTime":43,"children":44,"columnImage":45,"columnLogo":46,"uncheckedLogo":6,"checkedLogo":6,"isHot":42,"isHome":21,"forceLogin":21,"color":47,"seoTitle":48,"seoKeywords":49,"seoDescription":50,"contentNum":6,"promotionalPoster":51,"menuFrame":7,"innerLink":7,"parentView":7,"routeName":52,"routerPath":37,"componentInfo":38},"1986713082609147906","健康科普","article","/article.html","1","0","T",1,"2025-11-07 16:31:25",[],"https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:49/d4291d16-ed1c-48dd-84c8-ec1f85980b75.png","https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:52/6fe64094-9416-442c-a66d-032fb292666a.png","#c8e6ca","健康科普助力健康中国2030:共享健康知识新理念","健康科普, 健康中国, 科普知识, 健康家庭, 性健康, 营养健康, 运动健康, 科普宣传","探索健康科普在健康中国行动中的重要角色,了解最新的健康科普创新大赛、动漫及短视频,传播健康知识,助力全民健康。","https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:56/bd33f471-6c54-4d1b-a364-b06973dbc144.png","Article","癌症肿瘤,重大疾病",true,{"code":9,"msg":10,"message":6,"data":56,"success":54},{"pageNo":42,"pageSize":57,"result":58,"totalSize":21},10,[],{"code":9,"msg":10,"message":6,"data":60,"success":54},{"authors":61,"appraiseDimensionScoresVos":62},[],[]]