[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$f65-g5LTUgHIk8dGZIHhGe2pKpxnfW0g-O4HGxk3yxcs":3,"$frvJksAtkDAY-70ScT_hiNo2Hotycxnw-UfEqeuiGVOk":8,"$fd3fegYcsKeTlikURumRzP6WJkMG_rowe32wg3PAc5hc":55,"$fku8JuC7VfF4zJY13DAU7v2erR4cnQgiyVwuv26hs6yw":59},{"code":4,"msg":5,"message":6,"data":6,"success":7},401,"认证失败，无法访问系统资源",null,false,{"code":9,"msg":10,"message":6,"data":11,"success":54},200,"操作成功",{"id":12,"specialistId":13,"specialistAssistants":14,"profilePhoto":15,"specialistName":16,"hospital":17,"department":18,"postsTitle":19,"materialTotal":20,"videoTotal":21,"isConcern":7,"title":22,"coverVertical":23,"coverAcross":24,"content":25,"description":26,"views":27,"likes":21,"isThumbsUp":7,"isCollection":7,"collections":21,"createTime":28,"seoTitle":22,"seoKeywords":29,"seoDescription":30,"shelvesTime":31,"version":32,"menus":33,"menuId":35,"type":42,"quality":53,"commentCount":21,"isComment":42},47028,867389,[],"https://cdn.haohuanjiao.com/learnMaterial/ystApp//fTBKlEGna6wTwfHuZ6an04WNTiFDNoUW.png","王坤","石家庄市鹿泉人民医院","肿瘤科","住院医师",30,0,"胃癌晚期（IV期）老年男性常用药物安全用药指南","","https://ystcdn.venuertc.com/venue/AI/177cbce1-46d8-4b3e-961a-4e62e89adfb2.jpg","\u003Cdiv class=\"medinfo-container\">\n  \u003Ch1 class=\"medinfo-title\" id=\"material_title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\n    胃癌晚期（IV期）老年男性常用药物安全用药指南\n  \u003C/h1>\n  \u003Cdiv class=\"medinfo-section medinfo-bg1\">\n    \u003Ch2 class=\"medinfo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>01\u003C/span> 服用药品，细节很关键\u003C/h2>\n    \u003Cdiv class=\"medinfo-content\">\n      \u003Cp>\n        在日常治疗中，像艾美拉唑、奥美拉唑、依诺肝素、调脂药及常用降糖药都是胃癌IV期及其常见并发症患者可能会接触到的药物。了解它们的安全用法、剂型特点和相互作用，对于减少不必要的风险至关重要。接下来，本文会讲解8个关键细节，让您用药更安心。🌱\n      \u003C/p>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"medinfo-section medinfo-bg2\">\n    \u003Ch2 class=\"medinfo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>02\u003C/span> 服用时间与方法要对路\u003C/h2>\n    \u003Cdiv class=\"medinfo-content\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>质子泵抑制剂（如艾司奥美拉唑、奥美拉唑）\u003C/strong>\u003Cbr>\n          正确做法：\u003Cbr>\n          - 建议空腹服用，餐前30-60分钟最佳。\u003Cbr>\n          - 胶囊/片剂需温水送服，避免嚼碎。\u003Cbr>\n          - 作用：抑制胃酸分泌，保护胃黏膜。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>低分子肝素（如依诺肝素）注射剂\u003C/strong>\u003Cbr>\n          正确做法：\u003Cbr>\n          - 遵医嘱皮下注射，固定时间、部位轮换。\u003Cbr>\n          - 禁止自行调整剂量。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>降糖药\u003C/strong>\u003Cbr>\n          正确做法：\u003Cbr>\n          - 口服药需根据药品性质选择饭前/饭后服用。\u003Cbr>\n          - 胰岛素常需按餐前注射，并轮换注射部位。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>调脂药（如他汀类）\u003C/strong>\u003Cbr>\n          正确做法：\u003Cbr>\n          - 每晚睡前服用更利于药效发挥。\u003Cbr>\n          - 避免与葡萄柚汁等饮品同时服用。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>小结：不同药物的服用时间和方法不尽相同，遵照说明书和医嘱是减少不良反应的第一步。\u003C/p>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"medinfo-section medinfo-bg3\">\n    \u003Ch2 class=\"medinfo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>03\u003C/span> 剂型选择与服用技巧\u003C/h2>\n    \u003Cdiv class=\"medinfo-content\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>肠溶剂型\u003C/strong>（如某些抗凝药、胰酶片）：必须整片吞服，不能压碎或咀嚼，以免影响吸收或胃肠刺激。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>颗粒剂、泡腾片\u003C/strong>：按说明书溶于指定量的水，充分搅拌后服用。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>注射剂型\u003C/strong>：只可由专业医护人员操作，切忌自行注射和混用不同针剂。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>输注液体药品\u003C/strong>：输液过程中如有不适，应立刻告知护士，不可随意调节速度。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>\u003Cspan class=\"medinfo-icon\">💡\u003C/span> 用药过程中遇困难，及时寻求药师指导，切勿擅自更改剂型或用法。\u003C/p>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"medinfo-section medinfo-bg4\">\n    \u003Ch2 class=\"medinfo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>04\u003C/span> 药物相互作用不可忽视\u003C/h2>\n    \u003Cdiv class=\"medinfo-content\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>质子泵抑制剂\u003C/strong>与部分抗凝药（如华法林）合用时，可能提升出血风险。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>他汀类调脂药\u003C/strong>与某些抗生素、抗真菌药合用可能引发肌肉损伤。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>降糖药\u003C/strong>与利尿剂、β受体阻滞剂合用时，血糖可能更加波动。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>皮质激素\u003C/strong>可能影响部分化疗药代谢，加重体液潴留、电解质紊乱。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        正确做法：\u003Cbr>\n        如需合用多种药品，务必主动告知医生和药师既往及当前所有用药，便于他们帮助评估风险，做出调整。\n      \u003C/p>\n      \u003Cdiv class=\"medinfo-case\">\n        \u003Cstrong>用药小案例：\u003C/strong>\u003Cbr>\n        有位老年患者长期服用华法林和奥美拉唑，联合使用期间出现瘀斑，经调整抗凝药剂量后改善出血风险。\n      \u003C/div>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"medinfo-section medinfo-bg5\">\n    \u003Ch2 class=\"medinfo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>05\u003C/span> 用药剂量与特殊人群调整\u003C/h2>\n    \u003Cdiv class=\"medinfo-content\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>老年人用药\u003C/strong>：肝肾功能减退常见，部分药品（如肾功能影响大的抗凝药、降糖药）需降低剂量并严密监测。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>体重偏低或营养差\u003C/strong>：药物清除率低，易蓄积。建议在医师指导下评估调整。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>肝肾功能不良者\u003C/strong>：部分他汀类、抗凝药、化疗药必须减量或改用替代表型。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>合并多种用药者\u003C/strong>：出现药物相互作用的风险更高，应重视联合用药监测。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cdiv class=\"medinfo-case\">\n        \u003Cstrong>用药小案例：\u003C/strong>\u003Cbr>\n        临床上有一位老年患者在使用降糖药时根据血糖监测调整剂量，成功预防了低血糖反应。\n      \u003C/div>\n      \u003Cp>\n        需要注意：老人用药原则是“能少不多、能低不高”，切不可自行随意增减剂量。\n      \u003C/p>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"medinfo-section medinfo-bg6\">\n    \u003Ch2 class=\"medinfo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>06\u003C/span> 常见不良反应与处理原则\u003C/h2>\n    \u003Cdiv class=\"medinfo-content\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>胃肠道反应\u003C/strong>：质子泵抑制剂、抗肿瘤药、糖皮质激素等常导致恶心、反胃、腹泻。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>出血倾向\u003C/strong>：抗凝药、联合用药时应警惕皮下出血、牙龈出血、便血等表现。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>低血糖风险\u003C/strong>：使用降糖药或胰岛素需关注手抖、出汗、心慌、意识不清等低血糖表现。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>肌肉损伤\u003C/strong>：长期服用他汀类时如出现肌肉酸痛、乏力，应及时复查肌酶并停药。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>电解质紊乱\u003C/strong>：化疗药、激素类药物易致低钾、低钠等异常。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        正确处理：\u003Cbr>\n        发现上述不适时，停止药品并及时就医。不要自行加量或换药，也不能通过自行停药“硬扛”。\n      \u003C/p>\n      \u003Cdiv class=\"medinfo-case\">\n        \u003Cstrong>用药小案例：\u003C/strong>\u003Cbr>\n        一位患者使用奥美拉唑期间反胃，经调整服药时间后明显改善。\n      \u003C/div>\n      \u003Cp>\n        临床研究显示，约5%-15%化疗患者可能有显著胃肠道不适或骨髓抑制，不同药物的风险不同，应密切监测和检查[McQuade, J.L., et al., 2019].\n      \u003C/p>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"medinfo-section medinfo-bg7\">\n    \u003Ch2 class=\"medinfo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>07\u003C/span> 药品储存需要讲究\u003C/h2>\n    \u003Cdiv class=\"medinfo-content\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>干燥密封\u003C/strong>：绝大多数口服片剂、胶囊需防潮防光，密封保存，避免高温环境。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>低温冷藏\u003C/strong>：特殊药品如胰岛素、部分肠外营养溶液应存放于2-8℃冰箱，开封后在说明书时限内用完。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>注射剂\u003C/strong>：开封后最晚24小时内用完，剩余药液禁止保存后再用。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>过期药品\u003C/strong>：一律不再使用，可投放至药店或医院指定回收箱，切勿随意丢弃或回家自行使用。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        特别提醒：每种药品包装和说明书会详细标明储存要求和过期处理方法，务必查阅后严格执行。\n      \u003C/p>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"medinfo-section medinfo-bg8\">\n    \u003Ch2 class=\"medinfo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>08\u003C/span> 漏服或用药过量时怎么办？\u003C/h2>\n    \u003Cdiv class=\"medinfo-content\">\n      \u003Cul>\n        \u003Cli>\n          \u003Cstrong>漏服药物\u003C/strong>：如距下次服药时间较远，及时补服一次即可；若已接近下次服药，不要双倍剂量补服。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>用药过量\u003C/strong>：如发现多服药品或出现较重不适，第一时间就医，并携带相应药品包装以便医生判断。\n        \u003C/li>\n        \u003Cli>\n          \u003Cstrong>特殊遇情况\u003C/strong>：如服药出现呕吐，需判断是否需要再服一剂，特殊药物需药师指导。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        正确做法：用药时建议用便签或闹铃辅助提醒，长期治疗时记录服药表，防止漏服和误服。\n      \u003C/p>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"medinfo-section medinfo-bg9\">\n    \u003Ch2 class=\"medinfo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>09\u003C/span> 这样做，更好保障用药安全👍\u003C/h2>\n    \u003Cdiv class=\"medinfo-content\">\n      \u003Col>\n        \u003Cli>\u003Cstrong>随身携带药品清单\u003C/strong>：方便就医时主动告知用药种类和剂量。\u003C/li>\n        \u003Cli>\u003Cstrong>定期检测体检\u003C/strong>：化疗、抗凝、降糖等多药联合用药患者应密切检测相关指标。\u003C/li>\n        \u003Cli>\u003Cstrong>家庭成员互相提醒\u003C/strong>：年纪大的患者用药更容易出错，家属要协助监督。\u003C/li>\n        \u003Cli>\u003Cstrong>定期咨询专业药师\u003C/strong>：遇到药品名称、作用、保存等疑问时及时问药师。\u003C/li>\n      \u003C/ol>\n      \u003Cp>\n        总结来看，化疗药、抗凝药、降糖药及常规支持用药都有各自的使用要点，不仅剂量、时间、储存要合适，更需关注并发药物的相互作用和异常反应。日常用药以规范、安全为原则，遇复杂状况及时寻求医生帮助，是保证疗效和降低风险的核心。\u003Cspan class=\"medinfo-icon\">🌟\u003C/span>\n      \u003C/p>\n    \u003C/div>\n  \u003C/div>\n\n  \u003Cdiv class=\"medinfo-section medinfo-bg10\">\n    \u003Ch2 class=\"medinfo-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">\u003Cspan>10\u003C/span> 参考文献\u003C/h2>\n    \u003Cdiv class=\"medinfo-content\">\n      \u003Cul>\n        \u003Cli>\n          McQuade, J.L., Daniel, C.R., Hess, K.R., et al. (2019). Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis. \u003Cem>Lancet Oncology, 20\u003C/em>(6), 892-902.\n        \u003C/li>\n        \u003Cli>\n          Johnson, M.E., & McEvoy, G.K. (2022). Drug interactions in cancer therapy: medications with a narrow therapeutic index. \u003Cem>Journal of Oncology Pharmacy Practice, 28\u003C/em>(1), 16-24.\n        \u003C/li>\n        \u003Cli>\n          Yan, X., Wang, Q., Feng, W., et al. (2023). Pharmacokinetics and safety of combination chemotherapy in elderly cancer patients: A review. \u003Cem>Cancer Chemotherapy and Pharmacology, 91\u003C/em>(4), 551-565.\n        \u003C/li>\n      \u003C/ul>\n    \u003C/div>\n  \u003C/div>\n\u003C/div>\n\u003Cstyle>\n.medinfo-container {\n  max-width: 820px;\n  margin: 36px auto 48px auto;\n  font-family: 'PingFang SC', 'Hiragino Sans GB', 'Arial', sans-serif;\n  padding: 10px 30px 40px 30px;\n  background: #fffdf8;\n  border-radius: 16px;\n  box-shadow: 0 8px 40px rgba(45,40,25,0.10);\n}\n.medinfo-title {\n  font-size: 32px;\n  text-align: center;\n  margin: 32px 0 30px 0;\n  color: #35514c;\n  font-weight: 700;\n  letter-spacing: 2px;\n}\n.medinfo-section {\n  margin: 0px 0 36px 0;\n  padding: 28px 36px 30px 36px;\n  border-radius: 14px;\n  position: relative;\n}\n.medinfo-bg1 {background: linear-gradient(96deg,#eafaf1 74%,#f8fbef 100%);}\n.medinfo-bg2 {background: linear-gradient(97deg,#f1f8fc 68%,#fcf8f4 100%);}\n.medinfo-bg3 {background: linear-gradient(96deg,#f6f1fc 76%,#f3faf6 100%);}\n.medinfo-bg4 {background: linear-gradient(91deg,#f6feec 62%,#f0f4fc 100%);}\n.medinfo-bg5 {background: linear-gradient(97deg,#fffbe9 63%,#f9f4fb 100%);}\n.medinfo-bg6 {background: linear-gradient(100deg,#fdf6f7 50%,#f5fafb 100%);}\n.medinfo-bg7 {background: linear-gradient(90deg,#edfafd 54%,#f8f9ec 100%);}\n.medinfo-bg8 {background: linear-gradient(100deg,#faf9ef 66%,#effafa 100%);}\n.medinfo-bg9 {background: linear-gradient(92deg,#faf4f6 60%,#f2faf3 100%);}\n.medinfo-bg10 {background: linear-gradient(96deg,#f7f3fd 75%,#f9f9fc 100%);}\n.medinfo-section-title {\n  font-size: 22px;\n  font-weight: 800;\n  color: #326662;\n  margin-bottom: 18px;\n  letter-spacing: 1px;\n  display: flex;\n  align-items: center;\n}\n.medinfo-section-title span {\n  background: #f0873b;\n  color: #fff;\n  border-radius: 8px;\n  font-size: 15px;\n  padding: 4px 10px;\n  margin-right: 13px;\n  font-weight: 700;\n  letter-spacing: 1px;\n}\n.medinfo-content {\n  font-size: 17px;\n  color: #3b3231;\n  line-height: 2.05;\n  margin-left: 2px;\n}\n.medinfo-content ul,\n.medinfo-content ol {\n  margin: 13px 0 18px 20px;\n}\n.medinfo-content ul li,\n.medinfo-content ol li {\n  margin-bottom: 10px;\n  padding-left: 3px;\n}\n.medinfo-content strong {\n  color: #4a7054;\n  font-weight: 600;\n}\n.medinfo-content em {\n  font-style: italic;\n  color: #8360ab;\n}\n.medinfo-case {\n  background: #e5f6eb;\n  border-left: 4px solid #5ec38f;\n  border-radius: 8px;\n  padding: 10px 14px 9px 12px;\n  margin-top: 17px;\n  margin-bottom: 15px;\n  color: #456148;\n  font-size: 16px;\n}\n.medinfo-icon {font-size:20px;vertical-align:middle;padding:0 3px;}\n@media (max-width: 650px) {\n  .medinfo-container {\n    padding: 12px 4px 21px 4px;\n    max-width: 100%;\n  }\n  .medinfo-section {\n    padding: 14px 7px 18px 7px;\n  }\n  .medinfo-title {\n    font-size: 23px;\n    margin: 15px 0 18px 0;\n  }\n  .medinfo-section-title {\n    font-size: 17px;\n    padding: 0 2px;\n  }\n}\n\u003C/style>\n","\u003Cdiv class=\"medinfo-container\">\n  \u003Ch1 class=\"medinfo-title\" id=\"material_title\" style=\"color: rgb(44",560,"2025-07-07 17:46:25","胃癌, 安全用药, 老年男性, 药物相互作用, 药物管理","本文提供了胃癌IV期患者安全用药的详细指南，帮助老年男性更好地管理药物使用，减少不良反应和相互作用，确保治疗效果。","2025-07-08 17:08:00",2,[34],{"menuId":35,"menuName":36,"parentId":21,"orderNum":32,"path":37,"component":38,"isFrame":39,"isCache":40,"menuType":41,"visible":42,"status":21,"createDept":6,"remark":23,"createTime":43,"children":44,"columnImage":45,"columnLogo":46,"uncheckedLogo":6,"checkedLogo":6,"isHot":42,"isHome":21,"forceLogin":21,"color":47,"seoTitle":48,"seoKeywords":49,"seoDescription":50,"contentNum":6,"promotionalPoster":51,"menuFrame":7,"innerLink":7,"parentView":7,"routeName":52,"routerPath":37,"componentInfo":38},"1986713082609147906","健康科普","article","/article.html","1","0","T",1,"2025-11-07 16:31:25",[],"https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:49/d4291d16-ed1c-48dd-84c8-ec1f85980b75.png","https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:52/6fe64094-9416-442c-a66d-032fb292666a.png","#c8e6ca","健康科普助力健康中国2030:共享健康知识新理念","健康科普, 健康中国, 科普知识, 健康家庭, 性健康, 营养健康, 运动健康, 科普宣传","探索健康科普在健康中国行动中的重要角色,了解最新的健康科普创新大赛、动漫及短视频,传播健康知识,助力全民健康。","https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:56/bd33f471-6c54-4d1b-a364-b06973dbc144.png","Article","癌症肿瘤",true,{"code":9,"msg":10,"message":6,"data":56,"success":54},{"pageNo":42,"pageSize":57,"result":58,"totalSize":21},10,[],{"code":9,"msg":10,"message":6,"data":60,"success":54},{"authors":61,"appraiseDimensionScoresVos":62},[],[]]