[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$f65-g5LTUgHIk8dGZIHhGe2pKpxnfW0g-O4HGxk3yxcs":3,"$fBLj6FAGw1EdfP1YpskpqxiHH_RQRziPP2ldIys8nRc4":8,"$fxxpiYBEnkaaxMu6a86fZCrJzndCPgVnFT40ZcdE75K8":54,"$fB42ZcuntdIzFoKSsszMVH7KuDHkd1A59vjgVJ4hxLx0":58},{"code":4,"msg":5,"message":6,"data":6,"success":7},401,"认证失败，无法访问系统资源",null,false,{"code":9,"msg":10,"message":6,"data":11,"success":53},200,"操作成功",{"id":12,"specialistId":13,"specialistAssistants":14,"profilePhoto":15,"specialistName":16,"hospital":17,"department":18,"postsTitle":19,"materialTotal":20,"videoTotal":21,"isConcern":7,"title":22,"coverVertical":23,"coverAcross":24,"content":25,"description":25,"views":26,"likes":21,"isThumbsUp":7,"isCollection":7,"collections":21,"createTime":27,"seoTitle":22,"seoKeywords":28,"seoDescription":29,"shelvesTime":30,"version":31,"menus":32,"menuId":34,"type":41,"quality":52,"commentCount":21,"isComment":41},43966,869170,[],"https://cdn.haohuanjiao.com/learnMaterial/ystApp//i3z4Ip4S9vgWeB2cAErxS44yjGkqD3OR.png","杨景帅","东港市第二医院","肿瘤科","主治医师",7,0,"直肠癌局晚期常用药品安全用药指南","","https://ystcdn.venuertc.com/venue/AI/620478f3-cdef-45bf-9ce4-da487b662c8e.jpg","\u003Cdiv class=\"mrx-material-container\">\n  \u003Cdiv class=\"mrx-header-bg\">\n    \u003Ch1 id=\"material_title\" class=\"mrx-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">直肠癌局晚期常用药品安全用药指南\u003C/h1>\n    \u003Cdiv class=\"mrx-brief-intro\">\n      在直肠癌局晚期治疗中，化疗和靶向药物经常同时使用，这类药品怎么用才安全有效？本文将用5大核心要点，带你全面了解这些药物的正确用法、相互作用、不良反应及安全储存细节，帮你远离用药风险，更放心配合治疗。\n    \u003C/div>\n  \u003C/div>\n  \n  \u003C!-- 01 -->\n  \u003Csection class=\"mrx-section-bg\">\n    \u003Ch2 class=\"mrx-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">01  剂型区别与基本成分 🌱\u003C/h2>\n    \u003Cdiv class=\"mrx-content-block\">\n      \u003Cp>\n        在直肠癌局晚期治疗中，常用的化疗药有奥沙利铂、卡培他滨和氟尿嘧啶；靶向药物包括贝伐珠单抗、瑞戈非尼等。这些药品通常以注射剂、片剂或胶囊剂型出现。具体情况分为：\n      \u003C/p>\n      \u003Cul>\n        \u003Cli>\u003Cspan class=\"mrx-drug-point\">奥沙利铂：\u003C/span>注射用，常与氟尿嘧啶联用。\u003C/li>\n        \u003Cli>\u003Cspan class=\"mrx-drug-point\">卡培他滨：\u003C/span>口服片剂，用于辅助化疗或单独用药。\u003C/li>\n        \u003Cli>\u003Cspan class=\"mrx-drug-point\">氟尿嘧啶：\u003C/span>注射剂，适合连续输注。\u003C/li>\n        \u003Cli>\u003Cspan class=\"mrx-drug-point\">贝伐珠单抗、瑞戈非尼：\u003C/span>前者为注射剂，后者为口服片剂。\u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        \u003Cspan class=\"mrx-tip-emoji\">💡\u003C/span> \u003Cstrong>正确做法：\u003C/strong>使用前要仔细核对药品规格，严格遵医嘱选择剂型，切勿自行换药或拆分药片。\n      \u003C/p>\n    \u003C/div>\n  \u003C/section>\n\n  \u003C!-- 02 -->\n  \u003Csection class=\"mrx-section-bg\">\n    \u003Ch2 class=\"mrx-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">02  药物作用机制简述 🔬\u003C/h2>\n    \u003Cdiv class=\"mrx-content-block\">\n      \u003Cp>\n        每种药品都有其独特的作用机制，了解这些机制有助于合理用药：\n      \u003C/p>\n      \u003Cul>\n        \u003Cli>\u003Cspan class=\"mrx-drug-point\">奥沙利铂：\u003C/span>通过破坏肿瘤细胞的DNA，抑制细胞分裂。\u003C/li>\n        \u003Cli>\u003Cspan class=\"mrx-drug-point\">氟尿嘧啶、卡培他滨：\u003C/span>阻断肿瘤细胞的DNA和RNA合成，抑制增殖。\u003C/li>\n        \u003Cli>\u003Cspan class=\"mrx-drug-point\">贝伐珠单抗：\u003C/span>抑制新生血管生成，让肿瘤“断粮”。\u003C/li>\n        \u003Cli>\u003Cspan class=\"mrx-drug-point\">瑞戈非尼：\u003C/span>多靶点抑制剂，阻断肿瘤与相关信号传导。\u003C/li>\n      \u003C/ul>\n      \u003Cdiv class=\"mrx-case-block\">\n        \u003Cspan class=\"mrx-case-emoji\">📋\u003C/span> 临床上，有患者接受奥沙利铂与卡培他滨联合化疗，取得明显效果，但需严密监控不良反应。\n      \u003C/div>\n      \u003Cp>\n        \u003Cspan class=\"mrx-tip-emoji\">🚩\u003C/span>\u003Cstrong>特别提醒：\u003C/strong>作用机制不同，合理搭配联合用药才有助于提升治疗效果，请勿随意更换方案。\n      \u003C/p>\n    \u003C/div>\n  \u003C/section>\n  \n  \u003C!-- 03 -->\n  \u003Csection class=\"mrx-section-bg\">\n    \u003Ch2 class=\"mrx-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">03  正确用法用量及服药方法 🕒\u003C/h2>\n    \u003Cdiv class=\"mrx-content-block\">\n      \u003Cp>\n        化疗药多为周期性静脉滴注或每日口服，靶向药物有静脉滴注和口服，服药方法需特别关注：\n      \u003C/p>\n      \u003Cul>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">奥沙利铂：\u003C/span>静脉输注，一般每2-3周为一个疗程，需在医院操作，不能自行注射。\n        \u003C/li>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">氟尿嘧啶：\u003C/span>静脉滴注，每天定时投药，通常连续数天。\n        \u003C/li>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">卡培他滨：\u003C/span>每日两次，餐后30分钟内整片吞服，仅用清水送服，不能嚼碎或掰开。\n        \u003C/li>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">贝伐珠单抗：\u003C/span>静脉滴注，需严格控制滴注速度。\n        \u003C/li>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">瑞戈非尼：\u003C/span>餐后整片吞服，每日一次，建议同一时间服药。\u003C/li>\n      \u003C/ul>\n      \u003Cdiv class=\"mrx-case-block\">\n        \u003Cspan class=\"mrx-case-emoji\">🧑‍⚕️\u003C/span> 一位55岁男性患者在mFOLFOX6方案（含奥沙利铂、氟尿嘧啶、亚叶酸钙）及靶向治疗期间，因未按要求规律进食导致药物吸收波动，疗效及安全性均受影响。\n      \u003C/div>\n      \u003Cp>\n        \u003Cspan class=\"mrx-tip-emoji\">➤\u003C/span>\u003Cstrong>正确做法：\u003C/strong>务必按医嘱用药，不随意自行调整剂量或用法，用药期间定期复查。\n      \u003C/p>\n      \u003Cp>\n        \u003Cspan class=\"mrx-tip-emoji\">⚠️\u003C/span>\u003Cstrong>需要注意：\u003C/strong> 各类药品服用时间、方法和剂量差异较大，混淆极易引发风险，用药时应逐条记录清楚。\n      \u003C/p>\n    \u003C/div>\n  \u003C/section>\n  \n  \u003C!-- 04 -->\n  \u003Csection class=\"mrx-section-bg\">\n    \u003Ch2 class=\"mrx-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">04  药物相互作用与日常用药冲突 🧪\u003C/h2>\n    \u003Cdiv class=\"mrx-content-block\">\n      \u003Cp>\n        直肠癌治疗常见多种药物联合，药物相互作用复杂：\n      \u003C/p>\n      \u003Cul>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">卡培他滨：\u003C/span> 不建议与华法林、苯妥英同用，因会增加出血风险，需密切监测凝血功能。\n        \u003C/li>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">奥沙利铂：\u003C/span> 避免与强烈抑制肝酶的药物同用，影响药效和代谢，可增加神经毒性。\n        \u003C/li>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">贝伐珠单抗：\u003C/span> 联合其他化疗药品时，容易加重骨髓抑制反应。\n        \u003C/li>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">瑞戈非尼：\u003C/span> 不宜与强诱导或抑制CYP3A4的药物合用，例如果汁、某些抗生素等。\u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        \u003Cspan class=\"mrx-tip-emoji\">🔍\u003C/span> \u003Cstrong>正确做法：\u003C/strong> 所有药品的使用都应主动告知医生，包括保健品和中草药。\n      \u003C/p>\n      \u003Cp>\n        \u003Cspan class=\"mrx-tip-emoji\">📛\u003C/span>\u003Cstrong>特别提醒：\u003C/strong> 与任何新药同用前，务必查查说明书或咨询专业人员，防范意外。\n      \u003C/p>\n    \u003C/div>\n  \u003C/section>\n  \n  \u003C!-- 05 -->\n  \u003Csection class=\"mrx-section-bg\">\n    \u003Ch2 class=\"mrx-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">05  特殊人群与剂量调整 🚻\u003C/h2>\n    \u003Cdiv class=\"mrx-content-block\">\n      \u003Cp>\n        某些患者需根据自身条件调整剂量，安全用药很关键：\n      \u003C/p>\n      \u003Cul>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">老年患者：\u003C/span>肝肾功能减退时，奥沙利铂、氟尿嘧啶、卡培他滨均需适当减量，注意监测副作用。\n        \u003C/li>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">肝肾功能障碍者：\u003C/span>瑞戈非尼、卡培他滨须根据肾功能分级进行剂量调整，肝功能不良时应慎用。\n        \u003C/li>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">孕妇、哺乳期女性：\u003C/span>孕期、哺乳期禁止使用卡培他滨、奥沙利铂、氟尿嘧啶、贝伐珠单抗、瑞戈非尼等药，因具有较强生殖毒性。\n        \u003C/li>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">儿童：\u003C/span>上述药品一般不用于儿童，特殊仅在权威医师评估后可用。\n        \u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        \u003Cspan class=\"mrx-tip-emoji\">✔️\u003C/span>\u003Cstrong>正确做法：\u003C/strong>每位患者都应让医生详细评估自身药物耐受性，主动说明既往用药和身体异常情况。\n      \u003C/p>\n    \u003C/div>\n  \u003C/section>\n  \n  \u003C!-- 06 -->\n  \u003Csection class=\"mrx-section-bg\">\n    \u003Ch2 class=\"mrx-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">06  常见不良反应及应对措施 😷\u003C/h2>\n    \u003Cdiv class=\"mrx-content-block\">\n      \u003Cp>\n        化疗和靶向药不良反应多样，出现后务必高度重视。普通副作用如轻微皮疹、乏力常见，但有些严重不良反应需要立即处理：\n      \u003C/p>\n      \u003Cul>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">奥沙利铂：\u003C/span>手脚麻木、寒冷诱发疼痛、口腔炎等，部分患者表现为严重过敏反应。\n        \u003C/li>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">卡培他滨、氟尿嘧啶：\u003C/span>手足综合征、腹泻、口腔炎、白细胞和血小板下降。\n        \u003C/li>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">贝伐珠单抗：\u003C/span>高血压、蛋白尿、血栓等严重反应。\n        \u003C/li>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">瑞戈非尼：\u003C/span>皮疹、疲乏、口腔溃疡和肝功能异常。\u003C/li>\n      \u003C/ul>\n      \u003Cdiv class=\"mrx-case-block\">\n        \u003Cspan class=\"mrx-case-emoji\">📑\u003C/span> 一名患者在使用贝伐珠单抗时出现1级皮疹，经暂停一次用药和局部处理后恢复，用药继续随访监测。\n      \u003C/div>\n      \u003Cp>\n        \u003Cspan class=\"mrx-tip-emoji\">🌟\u003C/span>\u003Cstrong>正确做法：\u003C/strong>出现任何不良反应，应及时报告医生，特殊严重症状要立即前往医院救治，避免拖延。\n      \u003C/p>\n      \u003Cp>\n        \u003Cspan class=\"mrx-tip-emoji\">🛑\u003C/span>\u003Cstrong>警示：\u003C/strong>切勿因轻微副作用而私自停药或减量，错误操作易导致耐药或治疗失败。\n      \u003C/p>\n    \u003C/div>\n  \u003C/section>\n  \n  \u003C!-- 07 -->\n  \u003Csection class=\"mrx-section-bg\">\n    \u003Ch2 class=\"mrx-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">07  储存方式与过期处理 🔒\u003C/h2>\n    \u003Cdiv class=\"mrx-content-block\">\n      \u003Cp>\n        正确储存药品可维护药效，错误存放虽看似小事，实则影响巨大：\n      \u003C/p>\n      \u003Cul>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">注射剂：\u003C/span>如奥沙利铂、贝伐珠单抗，应按说明书避光冷藏（2-8℃），不可冷冻，更不可随意挪做他用。\u003C/li>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">口服片剂：\u003C/span>如卡培他滨、瑞戈非尼等，应密封、避光、阴凉干燥、远离儿童。\u003C/li>\n        \u003Cli>\n          \u003Cspan class=\"mrx-drug-point\">开封药品：\u003C/span>部分口服液或汤剂须在开封随用随弃，严禁超过规定时间或变质、湿片使用。\u003C/li>\n      \u003C/ul>\n      \u003Cp>\n        \u003Cspan class=\"mrx-tip-emoji\">🏷️\u003C/span>\u003Cstrong>正确做法：\u003C/strong>定期自查药品保质期，过期失效药品应统一交至药品回收点，严禁丢进生活垃圾，避免污染环境。\u003C/p>\n    \u003C/div>\n  \u003C/section>\n\n  \u003C!-- 总结 -->\n  \u003Csection class=\"mrx-summary-bg\">\n    \u003Ch2 class=\"mrx-section-title\" style=\"color: rgb(44, 62, 80); margin: 1.2em 0px 0.6em; font-weight: 700; border-bottom: 1px solid rgb(238, 238, 238);\">总结&用药提醒 🎯\u003C/h2>\n    \u003Cdiv class=\"mrx-content-block\">\n      \u003Cp>\n        化疗及靶向药物的规范应用是提升治疗效果和降低风险的关键所在。尤其在直肠癌局晚期联合用药时，剂型挑选、服药习惯、配伍禁忌、剂量调整及不良反应监控等每一环节都不能大意。\u003Cbr>\n        如果你正使用这些药品，最重要的两点请记住：\u003Cstrong>一是严格按照医生指示用药，每种药物必须分清时间、方法、剂量；二是遇到副作用和药品相关疑问要及时与医护人员联系，千万不要自行中断或替换治疗方案。\u003C/strong>\u003Cbr>\n        药品安全离不开每一位患者的参与和警觉，规范使用，才能得到最大益处。如果有不明之处，务必咨询相关专业人员，自己以及家人的健康都需要这份认真。\n      \u003C/p>\n    \u003C/div>\n  \u003C/section>\n\u003C/div>\n\n\u003Cstyle>\n.mrx-material-container {\n  font-family: 'PingFang SC', 'Microsoft YaHei', Arial, sans-serif;\n  background-color: #f6f7fb;\n  color: #2a2d37;\n  font-size: 16px;\n  line-height: 2;\n  padding: 0px 28px 24px 28px;\n  border-radius: 18px;\n  max-width: 840px;\n  margin: 38px auto 38px auto !important;\n  box-shadow: 0 4px 32px 0 rgba(178,182,212,0.12);\n  min-width: 360px;\n}\n\n.mrx-header-bg {\n  background: linear-gradient(120deg, #e2e3e9 40%, #e7eceb 100%);\n  padding: 38px 24px 26px 24px;\n  border-radius: 16px 16px 0 0;\n}\n\n.mrx-title {\n  margin-top: 0px;\n  font-size: 29px;\n  font-weight: 700;\n  color: #203168;\n  letter-spacing: 2.2px;\n  text-shadow: 1px 2px 8px #f7f8fa;\n}\n\n.mrx-brief-intro {\n  color: #3a4074;\n  font-size: 19px;\n  padding: 14px 0 0 3px;\n  border-left: 4px solid #85bcec;\n  margin-bottom: 7px;\n  margin-top: 8px;\n  font-weight: 500;\n  background: linear-gradient(90deg, #e9f1fa 70%, transparent);\n  border-radius: 10px;\n  padding-left: 11px;\n}\n\n.mrx-section-bg {\n  background: repeating-linear-gradient(105deg, #f4f6fa 0px, #f4f6fa 38px, #eceff4 38px, #eceff4 56px);\n  border-radius: 13px;\n  margin-top: 34px;\n  padding: 28px 28px 20px 28px;\n  box-shadow: 0 2px 9px 1px #f1f2fa;\n}\n\n.mrx-section-title {\n  font-size: 22px;\n  color: #266392;\n  font-weight: 600;\n  margin-top: 0px;\n  margin-bottom: 8px;\n  text-shadow: 0 2px 8px #e0e2e7;\n  letter-spacing: 1.1px;\n  padding-bottom: 3px;\n}\n\n.mrx-content-block {\n  margin-top: 4px;\n  font-size: 16.5px;\n}\n\n.mrx-content-block ul {\n  padding-left: 17px;\n  margin-bottom: 9px;\n  margin-top: 7px;\n}\n\n.mrx-content-block li {\n  margin-bottom: 0px;\n  padding-bottom: 0.8px;\n  padding-left: 0.8px;\n}\n\n.mrx-drug-point {\n  color: #498dd6;\n  font-weight: 600;\n}\n\n.mrx-tip-emoji {\n  font-size: 20px;\n  margin-right: 4px;\n  vertical-align: -3px;\n}\n\n.mrx-case-block {\n  background: linear-gradient(95deg, #bedcf7 60%, #f9fafc 100%);\n  font-size: 15.3px;\n  color: #254075;\n  padding: 8px 14px 9px 15px;\n  border-left: 5px solid #7b9be1;\n  border-radius: 8px;\n  margin: 15px 0px 14px 0px;\n  box-shadow: 0 1px 8px #e4ecfa;\n}\n\n.mrx-case-emoji {\n  font-size: 18px;\n  margin-right: 3px;\n  vertical-align: -3px;\n}\n\n.mrx-summary-bg {\n  background: linear-gradient(105deg, #f3efea 60%, #eaf2f7 100%);\n  border-radius: 16px;\n  margin-top: 36px;\n  padding: 26px 27px 17px 27px;\n  border-bottom: 2px solid #dadada;\n}\n\n.mrx-summary-bg .mrx-section-title {\n  color: #ba7a22;\n  text-shadow: 0 1.5px 8px #f4e7d1;\n}\n\n@media (max-width: 600px) {\n  .mrx-material-container {\n    padding: 0 2px 17px 2px;\n    margin-top: 15px !important;\n    border-radius: 7px;\n    min-width: 0;\n  }\n  .mrx-header-bg, .mrx-section-bg, .mrx-summary-bg {\n    padding-right: 6px;\n    padding-left: 7px;\n    border-radius: 7.5px;\n  }\n}\n\n\u003C/style>\n\n",507,"2025-06-28 11:09:58","直肠癌, 化疗药物, 靶向药物, 用药安全, 药物相互作用, 不良反应, 孕妇用药, 老年患者用药","了解直肠癌局晚期治疗中常用化疗和靶向药物的安全有效用法，包括剂型、用法、相互作用及不良反应，确保患者治疗过程的安全和有效。","2025-07-07 10:47:03",2,[33],{"menuId":34,"menuName":35,"parentId":21,"orderNum":31,"path":36,"component":37,"isFrame":38,"isCache":39,"menuType":40,"visible":41,"status":21,"createDept":6,"remark":23,"createTime":42,"children":43,"columnImage":44,"columnLogo":45,"uncheckedLogo":6,"checkedLogo":6,"isHot":41,"isHome":21,"forceLogin":21,"color":46,"seoTitle":47,"seoKeywords":48,"seoDescription":49,"contentNum":6,"promotionalPoster":50,"menuFrame":7,"innerLink":7,"parentView":7,"routeName":51,"routerPath":36,"componentInfo":37},"1986713082609147906","健康科普","article","/article.html","1","0","T",1,"2025-11-07 16:31:25",[],"https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:49/d4291d16-ed1c-48dd-84c8-ec1f85980b75.png","https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:52/6fe64094-9416-442c-a66d-032fb292666a.png","#c8e6ca","健康科普助力健康中国2030:共享健康知识新理念","健康科普, 健康中国, 科普知识, 健康家庭, 性健康, 营养健康, 运动健康, 科普宣传","探索健康科普在健康中国行动中的重要角色,了解最新的健康科普创新大赛、动漫及短视频,传播健康知识,助力全民健康。","https://ystcdn.venuertc.com/venue/undefined/2026-01-24-18:08:56/bd33f471-6c54-4d1b-a364-b06973dbc144.png","Article","癌症肿瘤,重大疾病",true,{"code":9,"msg":10,"message":6,"data":55,"success":53},{"pageNo":41,"pageSize":56,"result":57,"totalSize":21},10,[],{"code":9,"msg":10,"message":6,"data":59,"success":53},{"authors":60,"appraiseDimensionScoresVos":61},[],[]]